Breast cancer in the post-genomic era

por Swanton, C
Publicado 2010

Molecular classification of solid tumours: towards pathway-driven therapeutics

por Swanton, C, Caldas, C
Publicado 2009

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine

por Gerlinger, M, Swanton, C
Publicado 2010

Academically led clinical trials: challenges and opportunities

por Turajlic, S., Larkin, J., Swanton, C.
Publicado 2015

Cancer heterogeneity: implications for targeted therapeutics

por Fisher, R, Pusztai, L, Swanton, C
Publicado 2013

Circulating tumour DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer

por Abbosh, C, Swanton, C, Birkbak, N J
Publicado 2018

Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting

por Przewrocka, J., Rowan, A., Rosenthal, R., Kanu, N., Swanton, C.
Publicado 2020

Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic

por Chan, T A, Yarchoan, M, Jaffee, E, Swanton, C, Quezada, S A, Stenzinger, A, Peters, S
Publicado 2019

Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA

por Liu, M. C., Oxnard, G. R., Klein, E. A., Swanton, C., Seiden, M. V.
Publicado 2020

Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma

por Ghorani, E, Rosenthal, R, McGranahan, N, Reading, J L, Lynch, M, Peggs, K S, Swanton, C, Quezada, S A
Publicado 2018

Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution

por Venkatesan, S, Rosenthal, R, Kanu, N, McGranahan, N, Bartek, J, Quezada, S A, Hare, J, Harris, R S, Swanton, C
Publicado 2018

A retrospective analysis of clinical outcome of patients with chemo-refractory metastatic breast cancer treated in a single institution phase I unit

por Brunetto, A T, Sarker, D, Papadatos-Pastos, D, Fehrmann, R, Kaye, S B, Johnston, S, Allen, M, De Bono, J S, Swanton, C
Publicado 2010

The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer

por Middleton, G., Crack, L. R., Popat, S., Swanton, C., Hollingsworth, S. J., Buller, R., Walker, I., Carr, T. H., Wherton, D., Billingham, L. J.
Publicado 2015

Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions

por Zámborszky, J, Szikriszt, B, Gervai, J Z, Pipek, O, Póti, Á, Krzystanek, M, Ribli, D, Szalai-Gindl, J M, Csabai, I, Szallasi, Z, Swanton, C, Richardson, A L, Szüts, D
Publicado 2017

Erratum: Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions

por Zámborszky, J, Szikriszt, B, Gervai, J Z, Pipek, O, Póti, Á, Krzystanek, M, Ribli, D, Szalai-Gindl, J M, Csabai, I, Szallasi, Z, Swanton, C, Richardson, A L, Szüts, D
Publicado 2017

Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study

por Kurzrock, R., Bowles, D. W., Kang, H., Meric-Bernstam, F., Hainsworth, J., Spigel, D. R., Bose, R., Burris, H., Sweeney, C. J., Beattie, M. S., Blotner, S., Schulze, K., Cuchelkar, V., Swanton, C.
Publicado 2020

Cyclin D mediates tolerance of genome-doubling in cancers with functional p53

por Crockford, A., Zalmas, L. P., Grönroos, E., Dewhurst, S. M., McGranahan, N., Cuomo, M. E., Encheva, V., Snijders, A. P., Begum, J., Purewal, S., Cerveira, J., Patel, H., Renshaw, M. J., Swanton, C.
Publicado 2017

1557O Adaptive immunity to SARS-CoV-2 infection and vaccination in cancer patients: The CAPTURE study

por Shepherd, S.T.C., Fendler, A., Au, L., Byrne, F., Wilkinson, K., Wu, M., Schmitt, A.M., Joharatnam-Hogan, N., Shum, B., Del Rosario, L., Edmonds, K., Carlyle, E., Nicholson, E., Howell, M., Swanton, C., Walker, S., Kassiotis, G., Wilkinson, R., Larkin, J., Turajlic, S.
Publicado 2021

Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic

por Sud, A., Jones, M.E., Broggio, J., Loveday, C., Torr, B., Garrett, A., Nicol, D.L., Jhanji, S., Boyce, S.A., Gronthoud, F., Ward, P., Handy, J.M., Yousaf, N., Larkin, J., Suh, Y-E., Scott, S., Pharoah, P.D.P., Swanton, C., Abbosh, C., Williams, M., Lyratzopoulos, G., Houlston, R., Turnbull, C.
Publicado 2020

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome

por Favero, F., McGranahan, N., Salm, M., Birkbak, N. J., Sanborn, J. Z., Benz, S. C., Becq, J., Peden, J. F., Kingsbury, Z., Grocok, R. J., Humphray, S., Bentley, D., Spencer-Dene, B., Gutteridge, A., Brada, M., Roger, S., Dietrich, P.-Y., Forshew, T., Gerlinger, M., Rowan, A., Stamp, G., Eklund, A. C., Szallasi, Z., Swanton, C.
Publicado 2015