Ubiquitin modifications

por Swatek, Kirby N, Komander, David
Publicado 2016

Regulation of the Regulators: Post-Translational Modifications, Subcellular, and Spatiotemporal Distribution of Plant 14-3-3 Proteins

por Wilson, Rashaun S., Swatek, Kirby N., Thelen, Jay J.
Publicado 2016

Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling

por Michel, Martin A., Swatek, Kirby N., Hospenthal, Manuela K., Komander, David
Publicado 2017

“Scanning mutagenesis” of the amino acid sequences flanking phosphorylation site 1 of the mitochondrial pyruvate dehydrogenase complex

por Ahsan, Nagib, Swatek, Kirby N., Zhang, Jingfen, Miernyk, Ján A., Xu, Dong, Thelen, Jay J.
Publicado 2012

ISGylation-independent protection of cell growth by USP18 following interferon stimulation

por Clancy, Anne, Rusilowicz-Jones, Emma V., Wallace, Iona, Swatek, Kirby N., Urbé, Sylvie, Clague, Michael J.
Publicado 2023

Insights into the ISG15 transfer cascade by the UBE1L activating enzyme

por Wallace, Iona, Baek, Kheewoong, Prabu, J. Rajan, Vollrath, Ronnald, von Gronau, Susanne, Schulman, Brenda A., Swatek, Kirby N.
Publicado 2023

Identification of covalent modifications regulating immune signaling complex composition and phenotype

por Frauenstein, Annika, Ebner, Stefan, Hansen, Fynn M, Sinha, Ankit, Phulphagar, Kshiti, Swatek, Kirby, Hornburg, Daniel, Mann, Matthias, Meissner, Felix
Publicado 2021

OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death

por Damgaard, Rune Busk, Elliott, Paul R, Swatek, Kirby N, Maher, Eamonn R, Stepensky, Polina, Elpeleg, Orly, Komander, David, Berkun, Yackov
Publicado 2019

Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling

por Ordureau, Alban, Paulo, Joao A., Zhang, Jiuchun, An, Heeseon, Swatek, Kirby N., Cannon, Joe R., Wan, Qiaoqiao, Komander, David, Harper, J. Wade
Publicado 2020

Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin

por Michel, Martin A., Elliott, Paul R., Swatek, Kirby N., Simicek, Michal, Pruneda, Jonathan N., Wagstaff, Jane L., Freund, Stefan M.V., Komander, David
Publicado 2015

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

por Wauer, Tobias, Swatek, Kirby N, Wagstaff, Jane L, Gladkova, Christina, Pruneda, Jonathan N, Michel, Martin A, Gersch, Malte, Johnson, Christopher M, Freund, Stefan MV, Komander, David
Publicado 2015

The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules

por Alix, Eric, Godlee, Camilla, Cerny, Ondrej, Blundell, Samkeliso, Tocci, Romina, Matthews, Sophie, Liu, Mei, Pruneda, Jonathan N., Swatek, Kirby N., Komander, David, Sleap, Tabitha, Holden, David W.
Publicado 2020

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

por Swatek, Kirby N., Aumayr, Martina, Pruneda, Jonathan N., Visser, Linda J., Berryman, Stephen, Kueck, Anja F., Geurink, Paul P., Ovaa, Huib, van Kuppeveld, Frank J. M., Tuthill, Tobias J., Skern, Tim, Komander, David
Publicado 2018

Dissecting distinct proteolytic activities of FMDV L(pro) implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppr...

por Visser, Linda J., Aloise, Chiara, Swatek, Kirby N., Medina, Gisselle N., Olek, Karin M., Rabouw, Huib H., de Groot, Raoul J., Langereis, Martijn A., de los Santos, Teresa, Komander, David, Skern, Tim, van Kuppeveld, Frank J. M.
Publicado 2020

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2

por Annibaldi, Alessandro, Wicky John, Sidonie, Vanden Berghe, Tom, Swatek, Kirby N., Ruan, Jianbin, Liccardi, Gianmaria, Bianchi, Katiuscia, Elliott, Paul R., Choi, Sze Men, Van Coillie, Samya, Bertin, John, Wu, Hao, Komander, David, Vandenabeele, Peter, Silke, John, Meier, Pascal
Publicado 2018