Tipping the Balance in the Powerhouse of the Cell to “Protect” Colorectal Cancer

por Kidane, Dawit, Sweasy, Joann B.
Publicado 2012

Eukaryotic gene invasion by a bacterial mobile insertion sequence element IS2 during cloning into a plasmid vector

por Senejani, Alireza G, Sweasy, Joann B
Publicado 2010

Introduction

por Sweasy, Joann B., Glazer, Peter M.
Publicado 2013

Loop II of DNA polymerase beta is important for polymerization activity and fidelity

por Lin, George C., Jaeger, Joachim, Sweasy, Joann B.
Publicado 2007

The Leu22Pro tumor-associated variant of DNA polymerase beta is dRP lyase deficient

por Dalal, Shibani, Chikova, Anna, Jaeger, Joachim, Sweasy, Joann B.
Publicado 2008

The role of cysteines in the structure and function of OGG1

por Wang, Katarina, Maayah, Marah, Sweasy, Joann B., Alnajjar, Khadijeh S.
Publicado 2020

A Germline Polymorphism of DNA Polymerase Beta Induces Genomic Instability and Cellular Transformation

por Yamtich, Jennifer, Nemec, Antonia A., Keh, Agnes, Sweasy, Joann B.
Publicado 2012

Cellular Roles of DNA Polymerase Beta

por Ray, Sreerupa, Menezes, Miriam Rose, Senejani, Alireza, Sweasy, Joann B.
Publicado 2013

Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks

por Rozacky, Jenna, Nemec, Antoni A., Sweasy, Joann B., Kidane, Dawit
Publicado 2015

Kinesin 5B (KIF5B) Is Required for Progression through Female Meiosis and Proper Chromosomal Segregation in Mitotic Cells

por Kidane, Dawit, Sakkas, Denny, Nottoli, Timothy, McGrath, James, Sweasy, Joann B.
Publicado 2013

Crystal Structure of DNA Polymerase β with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating Position

por Eckenroth, Brian E., Fleming, Aaron M., Sweasy, Joann B., Burrows, Cynthia J., Doublié, Sylvie
Publicado 2014

DNA polymerase beta participates in DNA End-joining

por Ray, Sreerupa, Breuer, Gregory, DeVeaux, Michelle, Zelterman, Daniel, Bindra, Ranjit, Sweasy, Joann B
Publicado 2018

A Germline Polymorphism of Thymine DNA Glycosylase Induces Genomic Instability and Cellular Transformation

por Sjolund, Ashley, Nemec, Antonia A., Paquet, Nicolas, Prakash, Aishwarya, Sung, Patrick, Doublié, Sylvie, Sweasy, Joann B.
Publicado 2014

Expression of a germline variant in the N-terminal domain of the human DNA glycosylase NTHL1 induces cellular transformation without impairing enzymatic function or substrate speci...

por Marsden, Carolyn G., Jaruga, Pawel, Coskun, Erdem, Maher, Robyn L., Pederson, David S., Dizdaroglu, Miral, Sweasy, Joann B.
Publicado 2020

The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype

por Marsden, Carolyn G., Jensen, Ryan B., Zagelbaum, Jennifer, Rothenberg, Eli, Morrical, Scott W., Wallace, Susan S., Sweasy, Joann B.
Publicado 2016

Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase

por Chen, Jianhong, Morrical, Milagros D., Donigan, Katherine A., Weidhaas, Joanne B., Sweasy, Joann B., Averill, April M., Tomczak, Jennifer A., Morrical, Scott W.
Publicado 2015

The hematopoietic compartment is sufficient for lupus development resulting from the POLB-Y265C mutation

por Rahim, Tania, Levinson, Madison A., Carufe, Kelly E. W., Burak, Matthew, Meas, Rithy, Maher, Stephen, Bothwell, Alfred L. M., Gades, Naomi, Sweasy, Joann B.
Publicado 2022

The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation

por Galick, Heather A., Marsden, Carolyn G., Kathe, Scott, Dragon, Julie A., Volk, Lindsay, Nemec, Antonia A., Wallace, Susan S., Prakash, Aishwarya, Doublié, Sylvie, Sweasy, Joann B.
Publicado 2017

A pre-catalytic non-covalent step governs DNA polymerase β fidelity

por Alnajjar, Khadijeh S, Krylov, Ivan S, Negahbani, Amirsoheil, Haratipour, Pouya, Kashemirov, Boris A, Huang, Ji, Mahmoud, Mariam, McKenna, Charles E, Goodman, Myron F, Sweasy, Joann B
Publicado 2019

I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity

por Liptak, Cary, Mahmoud, Mariam M, Eckenroth, Brian E, Moreno, Marcus V, East, Kyle, Alnajjar, Khadijeh S, Huang, Ji, Towle-Weicksel, Jamie B, Doublié, Sylvie, Loria, J Patrick, Sweasy, Joann B
Publicado 2018