Mouse Ifit1b is a cap1-RNA–binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c

por Mears, Harriet V., Sweeney, Trevor R.
Publicado 2020

A Cell-based Fluorescence Resonance Energy Transfer (FRET) Sensor Reveals Inter- and Intragenogroup Variations in Norovirus Protease Activity and Polyprotein Cleavage

por Emmott, Edward, Sweeney, Trevor R., Goodfellow, Ian
Publicado 2015

Circularization of flavivirus genomic RNA inhibits de novo translation initiation

por Sanford, Thomas J, Mears, Harriet V, Fajardo, Teodoro, Locker, Nicolas, Sweeney, Trevor R
Publicado 2019

Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells

por Mears, Harriet V., Emmott, Edward, Chaudhry, Yasmin, Hosmillo, Myra, Goodfellow, Ian G., Sweeney, Trevor R.
Publicado 2019

Functional role and ribosomal position of the unique N-terminal region of DHX29, a factor required for initiation on structured mammalian mRNAs

por Sweeney, Trevor R, Dhote, Vidya, Guca, Ewelina, Hellen, Christopher U T, Hashem, Yaser, Pestova, Tatyana V
Publicado 2021

Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence

por Strnadova, Pavla, Ren, Hongwei, Valentine, Robert, Mazzon, Michela, Sweeney, Trevor R., Brierley, Ian, Smith, Geoffrey L.
Publicado 2015

The RNA Helicase eIF4A Is Required for Sapovirus Translation

por Hosmillo, Myra, Sweeney, Trevor R., Chaudhry, Yasmin, Leen, Eoin, Curry, Stephen, Goodfellow, Ian, Cho, Kyoung-Oh
Publicado 2016

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5′-terminal regions of cap0-, cap1- and 5′ppp- mRNAs

por Kumar, Parimal, Sweeney, Trevor R., Skabkin, Maxim A., Skabkina, Olga V., Hellen, Christopher U. T., Pestova, Tatyana V.
Publicado 2014

The flavivirus polymerase NS5 regulates translation of viral genomic RNA

por Fajardo, Teodoro, Sanford, Thomas J, Mears, Harriet V, Jasper, Annika, Storrie, Skye, Mansur, Daniel S, Sweeney, Trevor R
Publicado 2020

Foot-and-Mouth Disease Virus 2C Is a Hexameric AAA+ Protein with a Coordinated ATP Hydrolysis Mechanism

por Sweeney, Trevor R., Cisnetto, Valentina, Bose, Daniel, Bailey, Matthew, Wilson, Jon R., Zhang, Xiaodong, Belsham, Graham J., Curry, Stephen
Publicado 2010

IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA

por Fleith, Renata C, Mears, Harriet V, Leong, Xin Yun, Sanford, Thomas J, Emmott, Edward, Graham, Stephen C, Mansur, Daniel S, Sweeney, Trevor R
Publicado 2018

Insights into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate

por Zunszain, Patricia A., Knox, Stephen R., Sweeney, Trevor R., Yang, Jingjie, Roqué-Rosell, Núria, Belsham, Graham J., Leatherbarrow, Robin J., Curry, Stephen
Publicado 2010