Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca(++) dysregulation

por Decker, Jochen Martin, Krüger, Lars, Sydow, Astrid, Zhao, Shanting, Frotscher, Michael, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Publicado 2015

Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer’s disease mouse model

por Green, Claudia, Sydow, Astrid, Vogel, Stefanie, Anglada-Huguet, Marta, Wiedermann, Dirk, Mandelkow, Eckhard, Mandelkow, Eva-Maria, Hoehn, Mathias
Publicado 2019

Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy

por Anglada-Huguet, Marta, Endepols, Heike, Sydow, Astrid, Hilgers, Ronja, Neumaier, Bernd, Drzezga, Alexander, Kaniyappan, Senthilvelrajan, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Publicado 2023

Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD

por Sydow, Astrid, Hochgräfe, Katja, Könen, Stefanie, Cadinu, Daniela, Matenia, Dorthe, Petrova, Olga, Joseph, Maria, Dennissen, Frank Johannes, Mandelkow, Eva-Maria
Publicado 2016

Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau

por Hochgräfe, Katja, Sydow, Astrid, Matenia, Dorthe, Cadinu, Daniela, Könen, Stefanie, Petrova, Olga, Pickhardt, Marcus, Goll, Petra, Morellini, Fabio, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Publicado 2015