A Population Pharmacokinetic and Pharmacodynamic Analysis of Abemaciclib in a Phase I Clinical Trial in Cancer Patients

por Tate, Sonya C., Sykes, Amanda K., Kulanthaivel, Palaniappan, Chan, Edward M., Turner, P. Kellie, Cronier, Damien M.
Publicado 2017

SUMO Pathway Dependent Recruitment of Cellular Repressors to Herpes Simplex Virus Type 1 Genomes

por Cuchet-Lourenço, Delphine, Boutell, Chris, Lukashchuk, Vera, Grant, Kyle, Sykes, Amanda, Murray, Jill, Orr, Anne, Everett, Roger D.
Publicado 2011

Development and Application of a Mechanistic Population Modeling Approach to Describe Abemaciclib Pharmacokinetics

por Chigutsa, Emmanuel, Kambhampati, Siva Rama Prasad, Karen Sykes, Amanda, Posada, Maria M., van der Walt, Jan‐Stefan, Turner, P. Kellie
Publicado 2020

A Randomized Phase I Study of Abemaciclib in Chinese Patients with Advanced and/or Metastatic Cancers

por Zhang, Jian, Yang, Nong, Ji, Dongmei, Shen, Weina, Li, Wenhua, Han, Rubing, Wang, Ning, Tao, Haoxun, Chapman, Sonya C., Sykes, Amanda K., Zhang, Wanli, Hu, Xichun
Publicado 2021

A phase I study of tasisulam sodium (LY573636 sodium), a novel anticancer compound in patients with refractory solid tumors

por Simon, George R., Ilaria, Robert L., Sovak, Mika A., Williams, Charles C., Haura, Eric B., Cleverly, Ann L., Sykes, Amanda K., Wagner, Margaret M., de Alwis, Dinesh P., Slapak, Christopher A., Miller, Mary A., Spriggs, David R.
Publicado 2011