Structure of the Inhibitor W7 Bound to the Regulatory Domain of Cardiac Troponin C

por Hoffman, Ryan M. B., Sykes, Brian D.
Publicado 2009

Defining the Binding Site of Levosimendan and Its Analogues in a Regulatory Cardiac Troponin C−Troponin I Complex

por Robertson, Ian M., Baryshnikova, Olga K., Li, Monica X., Sykes, Brian D.
Publicado 2008

Probing the mechanism of cardiovascular drugs using a covalent levosimendan analog

por Pineda-Sanabria, Sandra E., Robertson, Ian M., Sun, Yin-Biao, Irving, Malcolm, Sykes, Brian D.
Publicado 2016

Thioimidate Bond Formation between Cardiac Troponin C and Nitrile-containing Compounds

por Klein, Brittney A., Robertson, Ian M., Reiz, Béla, Kampourakis, Thomas, Li, Liang, Sykes, Brian D.
Publicado 2019

The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q

por Robertson, Ian M., Sevrieva, Ivanka, Li, Monica X., Irving, Malcolm, Sun, Yin-Biao, Sykes, Brian D.
Publicado 2015

A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA

por Friis, R. Magnus N., Wu, Bob P., Reinke, Stacey N., Hockman, Darren J., Sykes, Brian D., Schultz, Michael C.
Publicado 2009

The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C

por Li, Monica X., Gelozia, Shorena, Danmaliki, Gaddafi I., Wen, Yurong, Liu, Philip B., Lemieux, M. Joanne, West, Frederick G., Sykes, Brian D., Hwang, Peter M.
Publicado 2018

A Common Phenotype Polymorphism in Mammalian Brains Defined by Concomitant Production of Prolactin and Growth Hormone

por Daude, Nathalie, Lee, Inyoul, Kim, Taek-Kyun, Janus, Christopher, Glaves, John Paul, Gapeshina, Hristina, Yang, Jing, Sykes, Brian D., Carlson, George A., Hood, Leroy E., Westaway, David
Publicado 2016

Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides

por Scotter, Andrew J, Guo, Meng, Tomczak, Melanie M, Daley, Margaret E, Campbell, Robert L, Oko, Richard J, Bateman, David A, Chakrabartty, Avijit, Sykes, Brian D, Davies, Peter L
Publicado 2007

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alle...

por Mercer, Robert C. C., Daude, Nathalie, Dorosh, Lyudmyla, Fu, Ze-Lin, Mays, Charles E., Gapeshina, Hristina, Wohlgemuth, Serene L., Acevedo-Morantes, Claudia Y., Yang, Jing, Cashman, Neil R., Coulthart, Michael B., Pearson, Dawn M., Joseph, Jeffrey T., Wille, Holger, Safar, Jiri G., Jansen, Gerard H., Stepanova, Maria, Sykes, Brian D., Westaway, David
Publicado 2018

Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling

por Elia, Josephine, Ungal, Grace, Kao, Charlly, Ambrosini, Alexander, De Jesus-Rosario, Nilsa, Larsen, Lene, Chiavacci, Rosetta, Wang, Tiancheng, Kurian, Christine, Titchen, Kanani, Sykes, Brian, Hwang, Sharon, Kumar, Bhumi, Potts, Jacqueline, Davis, Joshua, Malatack, Jeffrey, Slattery, Emma, Moorthy, Ganesh, Zuppa, Athena, Weller, Andrew, Byrne, Enda, Li, Yun R., Kraft, Walter K., Hakonarson, Hakon
Publicado 2018

HMDB: the Human Metabolome Database

por Wishart, David S., Tzur, Dan, Knox, Craig, Eisner, Roman, Guo, An Chi, Young, Nelson, Cheng, Dean, Jewell, Kevin, Arndt, David, Sawhney, Summit, Fung, Chris, Nikolai, Lisa, Lewis, Mike, Coutouly, Marie-Aude, Forsythe, Ian, Tang, Peter, Shrivastava, Savita, Jeroncic, Kevin, Stothard, Paul, Amegbey, Godwin, Block, David, Hau, David. D., Wagner, James, Miniaci, Jessica, Clements, Melisa, Gebremedhin, Mulu, Guo, Natalie, Zhang, Ying, Duggan, Gavin E., MacInnis, Glen D., Weljie, Alim M., Dowlatabadi, Reza, Bamforth, Fiona, Clive, Derrick, Greiner, Russ, Li, Liang, Marrie, Tom, Sykes, Brian D., Vogel, Hans J., Querengesser, Lori
Publicado 2007