Application of an Integrative Drug Safety Model for Detection of Adverse Drug Events Associated With Inhibition of Glutathione Peroxidase 1 in Chronic Obstructive Pulmonary Disease

por Janetzki, Jack L., Pratt, Nicole L., Ward, Michael B., Sykes, Matthew J.
Publicado 2023

Polymorphisms in the Mitochondrial Ribosome Recycling Factor EF-G2mt/MEF2 Compromise Cell Respiratory Function and Increase Atorvastatin Toxicity

por Callegari, Sylvie, Gregory, Philip A., Sykes, Matthew J., Bellon, Jennifer, Andrews, Stuart, McKinnon, Ross A., de Barros Lopes, Miguel A.
Publicado 2012

Discovery of N,4-Di(1H-pyrazol-4-yl)pyrimidin-2-amine-Derived CDK2 Inhibitors as Potential Anticancer Agents: Design, Synthesis, and Evaluation

por Fanta, Biruk Sintayehu, Lenjisa, Jimma, Teo, Theodosia, Kou, Lianmeng, Mekonnen, Laychiluh, Yang, Yuchao, Basnet, Sunita K. C., Hassankhani, Ramin, Sykes, Matthew J., Yu, Mingfeng, Wang, Shudong
Publicado 2023

Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division

por Chai, Wern Chern, Whittall, Jonathan J., Polyak, Steven W., Foo, Klyie, Li, Xin, Dutschke, Cameron J., Ogunniyi, Abiodun D., Ma, Shutao, Sykes, Matthew J., Semple, Susan J., Venter, Henrietta
Publicado 2022

Therapeutic Potential of a Novel Vitamin D(3) Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding

por Alshabrawy, Ali K., Cui, Yingjie, Sylvester, Cyan, Yang, Dongqing, Petito, Emilio S., Barratt, Kate R., Sawyer, Rebecca K., Heatlie, Jessica K., Polara, Ruhi, Sykes, Matthew J., Atkins, Gerald J., Hickey, Shane M., Wiese, Michael D., Stringer, Andrea M., Liu, Zhaopeng, Anderson, Paul H.
Publicado 2022