A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427

por Sykes, Melissa L, Avery, Vicky M
Publicado 2009

Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes

por Sykes, Melissa L., Avery, Vicky M.
Publicado 2015

3-pyridyl inhibitors with novel activity against Trypanosoma cruzi reveal in vitro profiles can aid prediction of putative cytochrome P450 inhibition

por Sykes, Melissa L., Avery, Vicky M.
Publicado 2018

Impact of Laboratory-Adapted Intracellular Trypanosoma cruzi Strains on the Activity Profiles of Compounds with Anti-T. cruzi Activity

por Sykes, Melissa L., Kennedy, Emily K., Avery, Vicky M.
Publicado 2023

Trypanocidal Activity of Marine Natural Products

por Jones, Amy J., Grkovic, Tanja, Sykes, Melissa L., Avery, Vicky M.
Publicado 2013

Temporal and Wash-Out Studies Identify Medicines for Malaria Venture Pathogen Box Compounds with Fast-Acting Activity against Both Trypanosoma cruzi and Trypanosoma brucei

por Sykes, Melissa L., Kennedy, Emily K., Read, Kevin D., Kaiser, Marcel, Avery, Vicky M.
Publicado 2022

Screening a Natural Product-Based Library against Kinetoplastid Parasites

por Zulfiqar, Bilal, Jones, Amy J., Sykes, Melissa L., Shelper, Todd B., Davis, Rohan A., Avery, Vicky M.
Publicado 2017

Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway

por Fletcher, Sabine, Lucantoni, Leonardo, Sykes, Melissa L., Jones, Amy J., Holleran, John P., Saliba, Kevin J., Avery, Vicky M.
Publicado 2016

Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado 2012

Correction: Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado 2013

Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery

por Duffy, Sandra, Sykes, Melissa L., Jones, Amy J., Shelper, Todd B., Simpson, Moana, Lang, Rebecca, Poulsen, Sally-Ann, Sleebs, Brad E., Avery, Vicky M.
Publicado 2017

Antitubercular and Antiparasitic 2-Nitroimidazopyrazinones with Improved Potency and Solubility

por Ang, Chee Wei, Tan, Lendl, Sykes, Melissa L., AbuGharbiyeh, Neda, Debnath, Anjan, Reid, Janet C., West, Nicholas P., Avery, Vicky M., Cooper, Matthew A., Blaskovich, Mark A. T.
Publicado 2020

Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis

por Hart, Christopher JS., Riches, Andrew G., Tiash, Snigdha, Abraham, Rebecca, Fayd’Herbe, Keely, Joch, Ellis, Zulfiqar, Bilal, Sykes, Melissa L., Avery, Vicky M., Šlapeta, Jan, Abraham, Sam, Ryan, John H., Skinner-Adams, Tina S.
Publicado 2023

Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity

por Jarrad, Angie M., Ang, Chee Wei, Debnath, Anjan, Hahn, Hye Jee, Woods, Kyra, Tan, Lendl, Sykes, Melissa L., Jones, Amy J., Pelingon, Ruby, Butler, Mark S., Avery, Vicky M., West, Nicholas P., Karoli, Tomislav, Blaskovich, Mark A. T., Cooper, Matthew A.
Publicado 2018