Fingerprinting Lymph Node Metastases

por Symmans, W. Fraser, Hortobagyi, Gabriel N.
Publicado 2008

Simple combination of multiple somatic variant callers to increase accuracy

por Trevarton, Alexander J., Chang, Jeffrey T., Symmans, W. Fraser
Publicado 2023

The Bimodality Index: A Criterion for Discovering and Ranking Bimodal Signatures from Cancer Gene Expression Profiling Data

por Wang, Jing, Wen, Sijin, Symmans, W. Fraser, Pusztai, Lajos, Coombes, Kevin R.
Publicado 2009

Accurate RNA Sequencing From Formalin-Fixed Cancer Tissue to Represent High-Quality Transcriptome From Frozen Tissue

por Li, Jialu, Fu, Chunxiao, Speed, Terence P., Wang, Wenyi, Symmans, W. Fraser
Publicado 2018

Lack of sufficiently strong informative features limits the potential of gene expression analysis as predictive tool for many clinical classification problems

por Hess, Kenneth R, Wei, Caimiao, Qi, Yuan, Iwamoto, Takayuki, Symmans, W Fraser, Pusztai, Lajos
Publicado 2011

Reproducibility of Variant Calls in Replicate Next Generation Sequencing Experiments

por Qi, Yuan, Liu, Xiuping, Liu, Chang-gong, Wang, Bailing, Hess, Kenneth R., Symmans, W. Fraser, Shi, Weiwei, Pusztai, Lajos
Publicado 2015

Evaluation of biological pathways involved in chemotherapy response in breast cancer

por Tordai, Attila, Wang, Jing, Andre, Fabrice, Liedtke, Cornelia, Yan, Kai, Sotiriou, Christos, Hortobagyi, Gabriel N, Symmans, W Fraser, Pusztai, Lajos
Publicado 2008

Maximum predictive power of the microarray-based models for clinical outcomes is limited by correlation between endpoint and gene expression profile

por Zhao, Chen, Shi, Leming, Tong, Weida, Shaughnessy, John D, Oberthuer, André, Pusztai, Lajos, Deng, Youping, Symmans, W Fraser, Shi, Tieliu
Publicado 2011

Maximizing biomarker discovery by minimizing gene signatures

por Chang, Chang, Wang, Junwei, Zhao, Chen, Fostel, Jennifer, Tong, Weida, Bushel, Pierre R, Deng, Youping, Pusztai, Lajos, Symmans, W Fraser, Shi, Tieliu
Publicado 2011

A Systematic Evaluation of Multi-Gene Predictors for the Pathological Response of Breast Cancer Patients to Chemotherapy

por Shen, Kui, Song, Nan, Kim, Youngchul, Tian, Chunqiao, Rice, Shara D., Gabrin, Michael J., Symmans, W. Fraser, Pusztai, Lajos, Lee, Jae K.
Publicado 2012

Evaluation of Sensitivity to Endocrine Therapy Index (SET2,3) for Response to Neoadjuvant Endocrine Therapy and Longer-Term Breast Cancer Patient Outcomes (Alliance Z1031)

por Suman, Vera J., Du, Lili, Hoskin, Tanya, Anurag, Meenakshi, Ma, Cynthia, Bedrosian, Isabelle, Hunt, Kelly K., Ellis, Matthew J., Symmans, W. Fraser
Publicado 2022

HER-2 low status in early-stage invasive lobular carcinoma of the breast: associated factors and outcomes in an institutional series

por Rothschild, Harriet T., Clelland, Elle, Patterson, Anne, Molina-Vega, Julissa, Kaur, Mandeep, Symmans, W. Fraser, Schwartz, Christopher J., Chien, A. Jo, Mukhtar, Rita A.
Publicado 2023

Bone metastasis-related signaling pathways in breast cancers stratified by estrogen receptor status

por Hayashi, Naoki, Iwamoto, Takayuki, Qi, Yuan, Niikura, Naoki, Santarpia, Libero, Yamauchi, Hideko, Nakamura, Seigo, Hortobagyi, Gabriel N., Pusztai, Lajos, Symmans, W. Fraser, Ueno, Naoto T.
Publicado 2017

The impact of RNA extraction method on accurate RNA sequencing from formalin-fixed paraffin-embedded tissues

por Marczyk, Michal, Fu, Chunxiao, Lau, Rosanna, Du, Lili, Trevarton, Alexander J., Sinn, Bruno V., Gould, Rebekah E., Pusztai, Lajos, Hatzis, Christos, Symmans, W. Fraser
Publicado 2019

Quantifying hormone receptor status in lobular breast cancer in an institutional series: the relationship between estrogen and progesterone receptor status and outcomes

por Clelland, Elle N., Rothschild, Harriet T., Patterson, Anne, Molina-Vega, Julissa, Kaur, Mandeep, Symmans, W. Fraser, Schwartz, Christopher J., Chien, A. Jo, Benz, Christopher C., Mukhtar, Rita A.
Publicado 2023

CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast...

por Esteva, Francisco J, Wang, Jing, Lin, Feng, Mejia, Jaime A, Yan, Kai, Altundag, Kadri, Valero, Vicente, Buzdar, Aman U, Hortobagyi, Gabriel N, Symmans, W Fraser, Pusztai, Lajos
Publicado 2007

Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response

por Li, Qiyuan, Eklund, Aron C, Birkbak, Nicolai J, Desmedt, Christine, Haibe-Kains, Benjamin, Sotiriou, Christos, Symmans, W Fraser, Pusztai, Lajos, Brunak, Søren, Richardson, Andrea L, Szallasi, Zoltan
Publicado 2011

Targeted RNAseq assay incorporating unique molecular identifiers for improved quantification of gene expression signatures and transcribed mutation fraction in fixed tumor samples

por Fu, Chunxiao, Marczyk, Michal, Samuels, Michael, Trevarton, Alexander J., Qu, Jiaxin, Lau, Rosanna, Du, Lili, Pappas, Todd, Sinn, Bruno V., Gould, Rebekah E., Pusztai, Lajos, Hatzis, Christos, Symmans, W. Fraser
Publicado 2021

Novel Functional Assay for Spindle-Assembly Checkpoint by Cyclin-Dependent Kinase Activity to Predict Taxane Chemosensitivity in Breast Tumor Patient

por Torikoshi, Yasuhiro, Gohda, Keigo, Davis, Michelle L., Symmans, W. Fraser, Pusztai, Lajos, Kazansky, Anna, Nakayama, Satoshi, Yoshida, Tomokazu, Matsushima, Tomoko, Hortobagyi, Gabriel N., Ishihara, Hideki, Kim, Seung Jin, Noguchi, Shinzaburo, Ueno, Naoto T.
Publicado 2013

PIK3CA-activating mutations and chemotherapy sensitivity in stage II–III breast cancer

por Liedtke, Cornelia, Cardone, Luca, Tordai, Attila, Yan, Kai, Gomez, Henry L, Figureoa, Luis J Barajas, Hubbard, Rebekah E, Valero, Vicente, Souchon, Eduardo A, Symmans, W Fraser, Hortobagyi, Gabriel N, Bardelli, Alberto, Pusztai, Lajos
Publicado 2008