Androgen Receptor Functional Analyses by High Throughput Imaging: Determination of Ligand, Cell Cycle, and Mutation-Specific Effects

por Szafran, Adam T., Szwarc, Maria, Marcelli, Marco, Mancini, Michael A.
Publicado 2008

Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures

por Szafran, Adam T., Mancini, Maureen G., Stossi, Fabio, Mancini, Michael A.
Publicado 2022

Leveraging Image-Derived Phenotypic Measurements for Drug-Target Interaction Predictions

por Kuthuru, Srikanth, Szafran, Adam T, Stossi, Fabio, Mancini, Michael A, Rao, Arvind
Publicado 2019

Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis

por Szafran, Adam T., Stossi, Fabio, Mancini, Maureen G., Walker, Cheryl L., Mancini, Michael A.
Publicado 2017

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α

por Bolt, Michael J., Singh, Pankaj, Obkirchner, Caroline E., Powell, Reid T., Mancini, Maureen G., Szafran, Adam T., Stossi, Fabio, Mancini, Michael A.
Publicado 2021

Quality Control for Single Cell Imaging Analytics Using Endocrine Disruptor-Induced Changes in Estrogen Receptor Expression

por Stossi, Fabio, Singh, Pankaj K., Mistry, Ragini M., Johnson, Hannah L., Dandekar, Radhika D., Mancini, Maureen G., Szafran, Adam T., Rao, Arvind U., Mancini, Michael A.
Publicado 2022

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms

por Mukherjee, Rajib, Beykal, Burcu, Szafran, Adam T., Onel, Melis, Stossi, Fabio, Mancini, Maureen G., Lloyd, Dillon, Wright, Fred A., Zhou, Lan, Mancini, Michael A., Pistikopoulos, Efstratios N.
Publicado 2020

Androgen Receptor Mutations Associated with Androgen Insensitivity Syndrome: A High Content Analysis Approach Leading to Personalized Medicine

por Szafran, Adam T., Hartig, Sean, Sun, Huiying, Uray, Ivan P., Szwarc, Maria, Shen, Yuqing, Mediwala, Sanjay N., Bell, Jennifer, McPhaul, Michael J., Mancini, Michael A., Marcelli, Marco
Publicado 2009

Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer

por Kaushik, Akash K., Shojaie, Ali, Panzitt, Katrin, Sonavane, Rajni, Venghatakrishnan, Harene, Manikkam, Mohan, Zaslavsky, Alexander, Putluri, Vasanta, Vasu, Vihas T., Zhang, Yiqing, Khan, Ayesha S., Lloyd, Stacy, Szafran, Adam T., Dasgupta, Subhamoy, Bader, David A., Stossi, Fabio, Li, Hangwen, Samanta, Susmita, Cao, Xuhong, Tsouko, Efrosini, Huang, Shixia, Frigo, Daniel E., Chan, Lawrence, Edwards, Dean P., Kaipparettu, Benny A., Mitsiades, Nicholas, Weigel, Nancy L., Mancini, Michael, McGuire, Sean E., Mehra, Rohit, Ittmann, Michael M., Chinnaiyan, Arul M., Putluri, Nagireddy, Palapattu, Ganesh S., Michailidis, George, Sreekumar, Arun
Publicado 2016