Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and i...

por Popovics, Petra, Schally, Andrew V., Szalontay, Luca, Block, Norman L., Rick, Ferenc G.
Publicado 2014

Inhibition of U-87 MG glioblastoma by AN-152 (AEZS-108), a targeted cytotoxic analog of luteinizing hormone-releasing hormone

por Jaszberenyi, Miklos, Schally, Andrew V., Block, Norman L., Nadji, Mehrdad, Vidaurre, Irving, Szalontay, Luca, Rick, Ferenc G.
Publicado 2013

Beneficial effects of novel antagonists of GHRH in different models of Alzheimer's disease

por Jaszberenyi, Miklos, Rick, Ferenc G., Szalontay, Luca, Block, Norman L., Zarandi, Marta, Cai, Ren-Zhi, Schally, Andrew V.
Publicado 2012

MODL-09. FEASIBILITY OF ACUTE SLICE CULTURE-SINGLE CELL SEQUENCING DRUG SCREENING AS A TOOL TO SELECT THERAPY FOR CHILDREN WITH RELAPSED BRAIN TUMORS

por Gampel, Bradley, Szalontay, Luca, Zhao, Wenting, Garvin, James, Sethi, Chankrit, Stark, Eileen, Sims, Peter, Canoll, Peter, Zacharoulis, Stergios
Publicado 2020

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108

por Szepeshazi, Karoly, Schally, Andrew V., Block, Norman L., Halmos, Gabor, Nadji, Mehrdad, Szalontay, Luca, Vidaurre, Irving, Abi-Chaker, Andrew, Rick, Ferenc G.
Publicado 2013

Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 (AEZS-108)

por Szepeshazi, Karoly, Schally, Andrew V., Keller, Gunhild, Block, Norman L., Benten, Daniel, Halmos, Gabor, Szalontay, Luca, Vidaurre, Irving, Jaszberenyi, Miklos, Rick, Ferenc G.
Publicado 2012

DDEL-07. A PHASE I STUDY EXAMINING THE FEASIBILITY OF INTERMITTENT CONVECTION-ENHANCED DELIVERY (CED) OF MTX110 FOR THE TREATMENT OF CHILDREN WITH NEWLY DIAGNOSED DIFFUSE MIDLINE G...

por Zacharoulis, Stergios, Szalontay, Luca, Higgins, Dominic, Englander, Zachary, Jin, ZhenZhen, Garvin, James, Zylber, Rebecca, Stark, Eileen, Maddocks, Alexis, Sethi, Chankrit, Canoll, Peter, Dammnett, Steve, Cook, Craig, Feldstein, Neil, Bruce, Jeffrey
Publicado 2020

New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor

por Kanashiro-Takeuchi, Rosemeire M., Szalontay, Luca, Schally, Andrew V., Takeuchi, Lauro M., Popovics, Petra, Jaszberenyi, Miklos, Vidaurre, Irving, Zarandi, Marta, Cai, Ren-Zhi, Block, Norman L., Hare, Joshua M., Rick, Ferenc G.
Publicado 2015

EPCT-23 PRE-CLINICAL STUDY OF FOCUSED ULTRASOUND-MEDIATED BLOOD-BRAIN BARRIER OPENING AND PANOBINOSTAT FOR DIFFUSE INTRINSIC PONTINE GLIOMA TREATMENT

por Wei, Hong-Jian, Pouliopoulos, Antonios, Yoh, Nina, Tazhibi, Masih, McQuillan, Nicholas, Zhang, Xu, Szalontay, Luca, Gartrell, Robyn, Pavisic, Jovana, Zhang, Zhiguo, Feldstein, Neil, Becher, Oren, Zacharoulis, Stergios, Konofagou, Elisa, Wu, Cheng-Chia
Publicado 2021

DDEL-07. A Phase I study examining the feasibility of intermittent convection-enhanced delivery (CED) of MTX110 for the treatment of children with newly diagnosed diffuse midline g...

por Zacharoulis, Stergios, Szalontay, Luca, CreveCoeur, Travis, Neira, Justin, Higgins, Dominique, Englander, Zachary, Spinazzi, Eleonora, Sethi, Chankrit, Canoll, Peter, Garvin, James, Zylber, Rebecca, Damment, Steve, Zamoryakhin, Dmitry, Maddocks, Alexis, Feldstein, Neil, Bruce, Jeffrey
Publicado 2022

Triple negative breast cancers express receptors for LHRH and are potential therapeutic targets for cytotoxic LHRH-analogs, AEZS 108 and AEZS 125

por Seitz, Stephan, Buchholz, Stefan, Schally, Andrew Victor, Weber, Florian, Klinkhammer-Schalke, Monika, Inwald, Elisabeth C, Perez, Roberto, Rick, Ferenc G, Szalontay, Luca, Hohla, Florian, Segerer, Sabine, Kwok, Chui Wai, Ortmann, Olaf, Engel, Jörg Bernhard
Publicado 2014

SURG-06. ENHANCED DELIVERY OF ANTI-PD1 FOR TREATMENT OF DIFFUSE MIDLINE GLIOMA USING FOCUSED ULTRASOUND-MEDIATED BLOOD-BRAIN BARRIER OPENING

por Kokossis, Danae, Wei, Hong-Jian, Gallitto, Matthew, Yoh, Nina, McQuillan, Nicholas, Tazhibi, Masih, Berg, Xander, Zhang, Xu, Szalontay, Luca, Gartrell, Robyn D, Pavisic, Jovana, Zhang, Zhiguo, Molotkov, Andrei, Mintz, Akiva, Konofagou, Elisa E, Wu, Cheng-Chia
Publicado 2023

DIPG-49. A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA

por Fernández, Ester Calvo, Wang, Junqiang, Zhang, Xu, Wei, Hong-Jian, Minns, Hanna, Griffin, Aaron, Obradovic, Aleksandar, Vlahos, Lukas, Martins, Timothy, Becker, Pamela, Crawford, John, Gartrell, Robyn, Szalontay, Luca, Zacharoulis, Stergios, Zhang, Zhiguo, Wechsler-Reya, Robert, Wu, Cheng-Chia, Califano, Andrea, Pavisic, Jovana
Publicado 2023

DIPG-45. Radiation induces a robust interferon response in Diffuse Midline Glioma (DMG), improving the potential for combination immunotherapy

por Minns, Hanna E, Padilla, Oscar, Wei, Hong-Jian, Webster-Carrion, Andrea, Tazhibi, Masih, McQuillan, Nicholas, Zhang, Xu, Yeh, Rebecca, Zhang, Zhiguo, Szalontay, Luca, Pavisic, Jovana, Garty, Guy, Garvin, James, Zacharoulis, Stergios, Canoll, Peter, Vanpouille-Box, Claire I, Menon, Vilas, Olah, Marta, Rabadan, Raul, Wu, Cheng-Chia, Gartrell, Robyn D
Publicado 2022

EPCT-21. NEXT-GENERATION SEQUENCING OF CEREBROSPINAL FLUID FOR CLINICAL MOLECULAR DIAGNOSTICS IN ADOLESCENT AND YOUNG ADULT (AYA) BRAIN TUMOR PATIENTS

por Miller, Alexandra, Szalontay, Luca, Bouvier, Nancy, Ahmed, Hamza, Hill, Katherine, Rafailov, Johnathan, Lee, Alex, Rodriguez-Sanchez, Irene, Yildirim, Onur, Patel, Arti, Bale, Tejus, Benayed, Ryma, Arcila, Maria, Donzelli, Maria, Dunkel, Ira, Gilheeney, Stephen, Khakoo, Yasmin, Kramer, Kim, Sait, Sameer F, Greenfield, Jeffrey, Souweidane, Mark, Haque, Sofia, Mauguen, Audrey, Berger, Michael, Mellinghoff, Ingo, Karajannis, Matthias
Publicado 2021

METB-05. NON-INVASIVE DIAGNOSIS OF BRAINSTEM GLIOMAS IN PEDIATRIC, ADOLESCENT, AND YOUNG ADULT PATIENTS THROUGH CEREBROSPINAL FLUID CELL-FREE DNA SEQUENCING

por Hill, Katherine, Giantini-Larsen, Alexandra, Hickman, Richard A, Holle, Bridget, Alano, Tina, Doe-Tetteh, Seyram, Bouvier, Nancy, Li, Shanita, Stockfisch, Emily, Huereca, Claudia, DiNapoli, Sara, Hertz, Charli Ann, Lee, Alex, Szalontay, Luca, Li, Bryan Kincheon, Riviere-Cazaux, Cecile, Burns, Terry C, Haque, Sofia, Bale, Tejus, Benhamida, Jamal, Dogan, Snjezana, Vanderbilt, Chad, Borsu, Laetitia, Ross, Dara, Chang, Jason, Zampieri, Caroline Barbosa, Donzelli, Maria, Dunkel, Ira J, Kramer, Kim, Sait, Sameer Farouk, Khakoo, Yasmin, Gilheeney, Stephen, Souweidane, Mark, Greenfield, Jeffery, Berger, Michael, Arcila, Maria, Ladanyi, Marc, Mellinghoff, Ingo, Karajannis, Matthias, Miller, Alexandra
Publicado 2023