Tensin4 is up-regulated by EGF-induced ERK1/2 activity and promotes cell proliferation and migration in hepatocellular carcinoma

por Chan, Lo-Kong, Chiu, Yung-Tuen, Sze, Karen Man-Fong, Ng, Irene Oi-Lin
Publicado 2015

Nuclear-Targeted Deleted in Liver Cancer 1 (DLC1) Is Less Efficient in Exerting Its Tumor Suppressive Activity Both In Vitro and In Vivo

por Chan, Lo-Kong, Ko, Frankie Chi Fat, Sze, Karen Man-Fong, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Publicado 2011

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma

por Tsui, Yu-Man, Sze, Karen Man-Fong, Tung, Edmund Kwok-Kwan, Ho, Daniel Wai-Hung, Lee, Terence Kin-Wah, Ng, Irene Oi-Lin
Publicado 2017

C-terminal truncated hepatitis B virus X protein regulates tumorigenicity, self-renewal and drug resistance via STAT3/Nanog signaling pathway

por Ching, Rachel Hiu Ha, Sze, Karen Man Fong, Lau, Eunice Yuen Ting, Chiu, Yung-Tuen, Lee, Joyce Man Fong, Ng, Irene Oi Lin, Lee, Terence Kin Wah
Publicado 2017

RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma

por Ma, Wei, Sze, Karen Man-Fong, Chan, Lo Kong, Lee, Joyce Man-Fong, Wei, Larry Lai, Wong, Chun-Ming, Lee, Terence Kin-Wah, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Publicado 2016

Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma

por Tian, Lu, Zhao, Luqing, Sze, Karen Man‐Fong, Kam, Charles Shing, Ming, Vanessa Sheung‐In, Wang, Xia, Zhang, Vanilla Xin, Ho, Daniel Wai‐Hung, Cheung, Tan‐To, Chan, Lo‐Kong, Ng, Irene Oi‐Lin
Publicado 2021

Midline 1 interacting protein 1 promotes cancer metastasis through FOS-like 1-mediated matrix metalloproteinase 9 signaling in HCC

por Chiu, Yung-Tuen, Husain, Abdullah, Sze, Karen Man-Fong, Ho, Daniel Wai-Hung, Suarez, Eliana Mary Senires, Wang, Xia, Lee, Eva, Ma, Hoi-Tang, Lee, Joyce Man-Fong, Chan, Lo-Kong, Ng, Irene Oi-Lin
Publicado 2023

Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1

por Zhang, Vanilla Xin, Sze, Karen Man-Fong, Chan, Lo-Kong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chiu, Yung-Tuen, Lee, Eva, Husain, Abdullah, Huang, Hongyang, Tian, Lu, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Publicado 2021

S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos

por Wang, Xia, Huang, Hongyang, Sze, Karen Man-Fong, Wang, Jin, Tian, Lu, Lu, Jingyi, Tsui, Yu-Man, Ma, Hoi Tang, Lee, Eva, Chen, Ao, Lee, Joyce, Wang, Ying, Yam, Judy Wai Ping, Cheung, Tan-To, Guan, Xinyuan, Ng, Irene Oi-Lin
Publicado 2023

PFKFB4 Drives the Oncogenicity in TP53-Mutated Hepatocellular Carcinoma in a Phosphatase-Dependent Manner

por Kam, Charles Shing, Ho, Daniel Wai-Hung, Ming, Vanessa Sheung-In, Tian, Lu, Sze, Karen Man-Fong, Zhang, Vanilla Xin, Tsui, Yu-Man, Husain, Abdullah, Lee, Joyce Man-Fong, Wong, Carmen Chak-Lui, Chan, Albert Chi-Yan, Cheung, Tan-To, Chan, Lo-Kong, Ng, Irene Oi-Lin
Publicado 2023

Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carc...

por Sze, Karen Man‐Fong, Ho, Daniel Wai‐Hung, Chiu, Yung‐Tuen, Tsui, Yu‐Man, Chan, Lo‐Kong, Lee, Joyce Man‐Fong, Chok, Kenneth Siu‐Ho, Chan, Albert Chi‐Yan, Tang, Chung‐Ngai, Tang, Victor Wai‐Lun, Lo, Irene Lai‐Oi, Yau, Derek Tsz‐Wai, Cheung, Tan‐To, Ng, Irene Oi‐Lin
Publicado 2020

Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer

por Tse, Aki Pui-Wah, Sze, Karen Man-Fong, Shea, Queenie Tsung-Kwan, Chiu, Elley Yung-Tuen, Tsang, Felice Ho-Ching, Chiu, David Kung-Chun, Zhang, Misty Shuo, Lee, Derek, Xu, Iris Ming-Jing, Chan, Cerise Yuen-Ki, Koh, Hui-Yu, Wong, Chun-Ming, Zheng, Yong-Ping, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Publicado 2018

Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma

por Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chan, Lo-Kong, Sze, Karen Man-Fong, Zhang, Xin, Cheu, Jacinth Wing-Sum, Chiu, Yung-Tuen, Lee, Joyce Man-Fong, Chan, Albert Chi-Yan, Cheung, Elaine Tin-Yan, Yau, Derek Tsz-Wai, Chia, Nam-Hung, Lo, Irene Lai-Oi, Sham, Pak-Chung, Cheung, Tan-To, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Publicado 2021