Functional effects of caloxin 1c2, a novel engineered selective inhibitor of plasma membrane Ca(2+)-pump isoform 4, on coronary artery

por Pande, Jyoti, Szewczyk, Magdalena M, Kuszczak, Iwona, Grover, Shawn, Escher, E, Grover, Ashok K
Publicado 2008

Ca(2+)-pumps and Na(+)–Ca(2+)-exchangers in coronary artery endothelium versus smooth muscle

por Szewczyk, Magdalena M, Davis, Kim A, Samson, Sue E, Simpson, Fiona, Rangachari, Patangi K, Grover, Ashok K
Publicado 2007

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

por Szewczyk, Magdalena M., Luciani, Genna M., Vu, Victoria, Murison, Alex, Dilworth, David, Barghout, Samir H., Lupien, Mathieu, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia
Publicado 2022

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

por Dahlin, Jayme L., Nelson, Kathryn M., Strasser, Jessica M., Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena M., Organ, Shawna, Cuellar, Matthew, Singh, Gurpreet, Shrimp, Jonathan H., Nguyen, Nghi, Meier, Jordan L., Arrowsmith, Cheryl H., Brown, Peter J., Baell, Jonathan B., Walters, Michael A.
Publicado 2017

Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6

por Harding, Rachel J., Franzoni, Ivan, Mann, Mandeep K., Szewczyk, Magdalena M., Mirabi, Bijan, Ferreira de Freitas, Renato, Owens, Dominic D. G., Ackloo, Suzanne, Scheremetjew, Alexej, Juarez-Ornelas, Kevin A., Sanichar, Randy, Baker, Rachel J., Dank, Christian, Brown, Peter J., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Schapira, Matthieu, Lautens, Mark, Arrowsmith, Cheryl H.
Publicado 2023

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

por Harding, Rachel J., Deme, Justin C., Hevler, Johannes F., Tamara, Sem, Lemak, Alexander, Cantle, Jeffrey P., Szewczyk, Magdalena M., Begeja, Nola, Goss, Siobhan, Zuo, Xiaobing, Loppnau, Peter, Seitova, Alma, Hutchinson, Ashley, Fan, Lixin, Truant, Ray, Schapira, Matthieu, Carroll, Jeffrey B., Heck, Albert J. R., Lea, Susan M., Arrowsmith, Cheryl H.
Publicado 2021

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

por Nakayama, Kazuhide, Szewczyk, Magdalena M., dela Sena, Carlo, Wu, Hong, Dong, Aiping, Zeng, Hong, Li, Fengling, de Freitas, Renato Ferreira, Eram, Mohammad S., Schapira, Matthieu, Baba, Yuji, Kunitomo, Mihoko, Cary, Douglas R., Tawada, Michiko, Ohashi, Akihiro, Imaeda, Yasuhiro, Saikatendu, Kumar Singh, Grimshaw, Charles E., Vedadi, Masoud, Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia, Kiba, Atsushi, Tomita, Daisuke, Brown, Peter J.
Publicado 2018

Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3)

por Kaniskan, H. Ümit, Eram, Mohammad S., Zhao, Kehao, Szewczyk, Magdalena M., Yang, Xiaobao, Schmidt, Keith, Luo, Xiao, Xiao, Sean, Dai, Miao, He, Feng, Zang, Irene, Lin, Ying, Li, Fengling, Dobrovetsky, Elena, Smil, David, Min, Sun-Joon, Lin-Jones, Jennifer, Schapira, Matthieu, Atadja, Peter, Li, En, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Brown, Peter J., Liu, Feng, Yu, Zhengtian, Vedadi, Masoud, Jin, Jian
Publicado 2017

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

por Szewczyk, Magdalena M., Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L., Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, dela Seña, Carlo C., Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Vedadi, Masoud, Brown, Peter J., Nara, Hiroshi, Barsyte-Lovejoy, Dalia
Publicado 2020

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

por Szewczyk, Magdalena M., Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L., Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, dela Seña, Carlo C., Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Vedadi, Masoud, Brown, Peter J., Nara, Hiroshi, Barsyte-Lovejoy, Dalia
Publicado 2020

Discovery of a chemical probe for PRDM9

por Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Ivanochko, Danton, Organ, Shawna L., Bok, Jabez, Ho, Jessica Sook Yuin, Gay, Florence P. H., Li, Fengling, Blazer, Levi, Eram, Mohammad S., Halabelian, Levon, Dilworth, David, Luciani, Genna M., Lima-Fernandes, Evelyne, Wu, Qin, Loppnau, Peter, Palmer, Nathan, Talib, S. Zakiah A., Brown, Peter J., Schapira, Matthieu, Kaldis, Philipp, O’Hagan, Ronan C., Guccione, Ernesto, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Sanders, John M., Kattar, Solomon D., Bennett, D. Jonathan, Nicholson, Benjamin, Vedadi, Masoud
Publicado 2019

PRMT inhibition induces a viral mimicry response in triple-negative breast cancer

por Wu, Qin, Nie, David Y., Ba-alawi, Wail, Ji, YiShuai, Zhang, ZiWen, Cruickshank, Jennifer, Haight, Jillian, Ciamponi, Felipe E., Chen, Jocelyn, Duan, Shili, Shen, Yudao, Liu, Jing, Marhon, Sajid A., Mehdipour, Parinaz, Szewczyk, Magdalena M., Dogan-Artun, Nergiz, Chen, WenJun, Zhang, Lan Xin, Deblois, Genevieve, Prinos, Panagiotis, Massirer, Katlin B., Barsyte-Lovejoy, Dalia, Jin, Jian, De Carvalho, Daniel D., Haibe-Kains, Benjamin, Wang, XiaoJia, Cescon, David W., Lupien, Mathieu, Arrowsmith, Cheryl H.
Publicado 2022

Discovery of Nanomolar DCAF1 Small Molecule Ligands

por Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud
Publicado 2023