Leukotriene A4 hydrolase inhibition improves age-related cognitive decline via modulation of synaptic function

por Adams, Julia M., Rege, Sanket V., Liu, Angela T., Vu, Ninh V., Raina, Sharda, Kirsher, Douglas Y., Nguyen, Amy L., Harish, Reema, Szoke, Balazs, Leone, Dino P., Czirr, Eva, Braithwaite, Steven, Kerrisk Campbell, Meghan
Publicado 2023

CCR3 plays a role in murine age-related cognitive changes and T-cell infiltration into the brain

por Rege, Sanket V., Teichert, Arnaud, Masumi, Juliet, Dhande, Onkar S., Harish, Reema, Higgins, Brett W., Lopez, Yesenia, Akrapongpisak, Lily, Hackbart, Hannah, Caryotakis, Sofia, Leone, Dino P., Szoke, Balazs, Hannestad, Jonas, Nikolich, Karoly, Braithwaite, Steven P., Minami, S. Sakura
Publicado 2023

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions

por Tóth, Gergely, Neumann, Thomas, Berthet, Amandine, Masliah, Eliezer, Spencer, Brian, Tao, Jiahui, Jobling, Michael F., Gardai, Shyra J., Bertoncini, Carlos W., Cremades, Nunilo, Bova, Michael, Ballaron, Stephen, Chen, Xiao-Hua, Mao, Wenxian, Nguyen, Phuong, Tabios, Mariano C., Tambe, Mitali A., Rochet, Jean-Christophe, Junker, Hans-Dieter, Schwizer, Daniel, Sekul, Renate, Ott, Inge, Anderson, John P., Szoke, Balazs, Hoffman, Wherly, Christodoulou, John, Yednock, Ted, Agard, David A., Schenk, Dale, McConlogue, Lisa
Publicado 2019

Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease

por Basi, Guriqbal S, Hemphill, Susanna, Brigham, Elizabeth F, Liao, Anna, Aubele, Danielle L, Baker, Jeanne, Barbour, Robin, Bova, Michael, Chen, Xiao-Hua, Dappen, Michael S, Eichenbaum, Tovah, Goldbach, Erich, Hawkinson, Jon, Lawler-Herbold, Rose, Hu, Kang, Hui, Terence, Jagodzinski, Jacek J, Keim, Pamela S, Kholodenko, Dora, Latimer, Lee H, Lee, Mike, Marugg, Jennifer, Mattson, Matthew N, McCauley, Scott, Miller, James L, Motter, Ruth, Mutter, Linda, Neitzel, Martin L, Ni, Huifang, Nguyen, Lan, Quinn, Kevin, Ruslim, Lany, Semko, Christopher M, Shapiro, Paul, Smith, Jenifer, Soriano, Ferdie, Szoke, Balazs, Tanaka, Kevin, Tang, Pearl, Tucker, John A, Ye, Xiacong Michael, Yu, Mei, Wu, Jing, Xu, Ying-zi, Garofalo, Albert W, Sauer, John Michael, Konradi, Andrei W, Ness, Daniel, Shopp, George, Pleiss, Michael A, Freedman, Stephen B, Schenk, Dale
Publicado 2010