Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase

por Bai, Aiping, Mao, Cungui, Jenkins, Russell W., Szulc, Zdzislaw M., Bielawska, Alicja, Hannun, Yusuf A.
Publicado 2017

C(16)-ceramide is a natural regulatory ligand of p53 in cellular stress response

por Fekry, Baharan, Jeffries, Kristen A., Esmaeilniakooshkghazi, Amin, Szulc, Zdzislaw M., Knagge, Kevin J., Kirchner, David R., Horita, David A., Krupenko, Sergey A., Krupenko, Natalia I.
Publicado 2018

Distinctive sphingolipid patterns in chronic multiple sclerosis lesions

por Podbielska, Maria, Szulc, Zdzislaw M., Ariga, Toshio, Pokryszko-Dragan, Anna, Fortuna, Wojciech, Bilinska, Małgorzata, Podemski, Ryszard, Jaskiewicz, Ewa, Kurowska, Ewa, Yu, Robert K., Hogan, Edward L.
Publicado 2020

Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects

por Oleinik, Natalia, Albayram, Onder, Kassir, Mohamed Faisal, Atilgan, F. Cansu, Walton, Chase, Karakaya, Eda, Kurtz, John, Alekseyenko, Alexander, Alsudani, Habeeb, Sheridan, Megan, Szulc, Zdzislaw M., Ogretmen, Besim
Publicado 2023

HPV/E7 induces chemotherapy‐mediated tumor suppression by ceramide‐dependent mitophagy

por Thomas, Raquela J, Oleinik, Natalia, Panneer Selvam, Shanmugam, Vaena, Silvia G, Dany, Mohammed, Nganga, Rose N, Depalma, Ryan, Baron, Kyla D, Kim, Jisun, Szulc, Zdzislaw M, Ogretmen, Besim
Publicado 2017

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

por Sentelle, R. David, Senkal, Can E., Jiang, Wenhui, Ponnusamy, Suriyan, Gencer, Salih, Selvam, Shanmugam Panneer, Ramshesh, Venkat K., Peterson, Yuri K., Lemasters, John J., Szulc, Zdzislaw M., Bielawski, Jacek, Ogretmen, Besim
Publicado 2012

Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis

por Saddoughi, Sahar A, Gencer, Salih, Peterson, Yuri K, Ward, Katherine E, Mukhopadhyay, Archana, Oaks, Joshua, Bielawski, Jacek, Szulc, Zdzislaw M, Thomas, Raquela J, Selvam, Shanmugam P, Senkal, Can E, Garrett-Mayer, Elizabeth, De Palma, Ryan M, Fedarovich, Dzmitry, Liu, Angen, Habib, Amyn A, Stahelin, Robert V, Perrotti, Danilo, Ogretmen, Besim
Publicado 2013