Folic Acid-Metabolizing Enzymes Regulate the Antitumor Effect of 5-Fluoro-2′-Deoxyuridine in Colorectal Cancer Cell Lines

por Tsukihara, Hiroshi, Tsunekuni, Kenta, Takechi, Teiji
Publicado 2016

Trifluridine/tipiracil increases survival rates in peritoneal dissemination mouse models of human colorectal and gastric cancer

por Suzuki, Norihiko, Nakagawa, Fumio, Takechi, Teiji
Publicado 2017

Trifluridine/tipiracil increases survival rates in peritoneal dissemination mouse models of human colorectal and gastric cancer

por Suzuki, Norihiko, Nakagawa, Fumio, Takechi, Teiji
Publicado 2021

Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis

por SHIMAMOTO, YUJI, NUKATSUKA, MAMORU, TAKECHI, TEIJI, FUKUSHIMA, MASAKAZU
Publicado 2016

Effect of a novel oral chemotherapeutic agent containing a combination of trifluridine, tipiracil and the novel triple angiokinase inhibitor nintedanib, on human colorectal cancer...

por Suzuki, Norihiko, Nakagawa, Fumio, Matsuoka, Kazuaki, Takechi, Teiji
Publicado 2016

Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression

por Matsuoka, Kazuaki, Nakagawa, Fumio, Kobunai, Takashi, Takechi, Teiji
Publicado 2018

Screening of Differentially Expressed Genes in 5‐Fluorouracil‐resistant Human Gastrointestinal Tumor Cells

por Takechi, Teiji, Koizumi, Katsuhisa, Tsujimoto, Hiroaki, Fukushima, Masakazu
Publicado 2001

5‐Chloro‐2,4‐dihydroxypyridine, CDHP, prevents lung metastasis of basal‐like breast cancer cells by reducing nascent adhesion formation

por Itou, Junji, Tsukihara, Hiroshi, Nukatsuka, Mamoru, Toi, Masakazu, Takechi, Teiji
Publicado 2018

Relationship between Protein Levels and Gene Expression of Dihydropyrimidine Dehydrogenase in Human Tumor Cells during Growth in Culture and in Nude Mice

por Takechi, Teiji, Okabe, Hiroyuki, Fujioka, Akio, Murakami, Yuko, Fukushima, Masakazu
Publicado 1998

Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells

por Matsuoka, Kazuaki, Nakagawa, Fumio, Tanaka, Nozomu, Okabe, Hiroyuki, Matsuo, Kenichi, Takechi, Teiji
Publicado 2018

Enhancement of 5-fluorouracil-induced cytotoxicity by leucovorin in 5-fluorouracil-resistant gastric cancer cells with upregulated expression of thymidylate synthase

por Nakamura, Ayako, Nakajima, Go, Okuyama, Ryuji, Kuramochi, Hidekazu, Kondoh, Yurin, Kanemura, Toshinori, Takechi, Teiji, Yamamoto, Masakazu, Hayashi, Kazuhiko
Publicado 2013

Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts

por TSUKIHARA, HIROSHI, NAKAGAWA, FUMIO, SAKAMOTO, KAZUKI, ISHIDA, KEIJI, TANAKA, NOZOMU, OKABE, HIROYUKI, UCHIDA, JUNJI, MATSUO, KENICHI, TAKECHI, TEIJI
Publicado 2015

MicroRNA profiles involved in trifluridine resistance

por Tsunekuni, Kenta, Konno, Masamitsu, Asai, Ayumu, Koseki, Jun, Kobunai, Takashi, Takechi, Teiji, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2017

Dihydropyrimidine Dehydrogenase and Messenger RNA Levels in Gastric Cancer: Possible Predictor for Sensitivity to 5‐Fluorouracil

por Ishikawa, Yoichiro, Kubota, Tetsuro, Otani, Yoshihide, Watanabe, Masahiko, Teramoto, Tatsuo, Kumai, Koichiro, Takechi, Teiji, Okabe, Hiroyuki, Fukushima, Masakazu, Kitajima, Masaki
Publicado 2000

CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure

por Tsunekuni, Kenta, Konno, Masamitsu, Haraguchi, Naotsugu, Koseki, Jun, Asai, Ayumu, Matsuoka, Kazuaki, Kobunai, Takashi, Takechi, Teiji, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2019

Quantitative Measurement of Thymidylate Synthase and Dihydropyrimidine Dehydrogenase mRNA Level in Gastric Cancer by Real‐time RT‐PCR

por Fujiwara, Hisataka, Terashima, Masanori, Irinoda, Takashi, Takagane, Akinori, Abe, Kaoru, Kashiwaba, Masahiro, Oyama, Kennichi, Takahashi, Masanori, Maesawa, Chihaya, Saito, Kazuyoshi, Takechi, Teiji, Fukushima, Masakazu
Publicado 2002

Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil

por Ishida, Kaoru, Ito, Chie, Ohmori, Yukimi, Kume, Kohei, Sato, Kei A., Koizumi, Yuka, Konta, Akari, Iwaya, Takeshi, Nukatsuka, Mamoru, Kobunai, Takashi, Takechi, Teiji, Nishizuka, Satoshi S.
Publicado 2017