Mechanisms of resistance to immune checkpoint inhibitors

por Nagasaki, Joji, Ishino, Takamasa, Togashi, Yosuke
Publicado 2022

Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: current evidence

por Togashi, Yosuke, Hayashi, Hidetoshi, Nakagawa, Kazuhiko, Nishio, Kazuto
Publicado 2014

Editorial: Strategies to overcome tumor evasion and resistance to immunotherapies by targeting immune suppressor cells

por Saida, Yu, Watanabe, Satoshi, Koyama, Shohei, Togashi, Yosuke, Kikuchi, Toshiaki
Publicado 2023

Continuous morphine infusion for end-stage lung cancer patients

por KIM, YOUNG HAK, OKUDA, CHIYUKI, SAKAMORI, YUICHI, MASAGO, KATSUHIRO, TOGASHI, YOSUKE, MISHIMA, MICHIAKI
Publicado 2013

Activated CTLA‐4‐independent immunosuppression of Treg cells disturbs CTLA‐4 blockade‐mediated antitumor immunity

por Watanabe, Tomofumi, Ishino, Takamasa, Ueda, Youki, Nagasaki, Joji, Sadahira, Takuya, Dansako, Hiromichi, Araki, Motoo, Togashi, Yosuke
Publicado 2023

Synergistic antitumor effects of S-1 with eribulin in vitro and in vivo for triple-negative breast cancer cell lines

por Terashima, Masato, Sakai, Kazuko, Togashi, Yosuke, Hayashi, Hidetoshi, De Velasco, Marco A, Tsurutani, Junji, Nishio, Kazuto
Publicado 2014

KIAA1199 interacts with glycogen phosphorylase kinase β-subunit (PHKB) to promote glycogen breakdown and cancer cell survival

por Terashima, Masato, Fujita, Yoshihiko, Togashi, Yosuke, Sakai, Kazuko, De Velasco, Marco A., Tomida, Shuta, Nishio, Kazuto
Publicado 2014

Combination therapy with hydrogen peroxide and irradiation promotes an abscopal effect in mouse models

por Kemmotsu, Naoya, Zhu, Li, Nagasaki, Joji, Otani, Yoshihiro, Ueda, Youki, Dansako, Hiromichi, Fang, Yue, Date, Isao, Togashi, Yosuke
Publicado 2023

Pneumocystis jiroveci pneumonia and colonization in patients with advanced lung cancer

por TOGASHI, YOSUKE, MASAGO, KATSUHIRO, ITO, YUTAKA, SAKAMORI, YUICHI, OKUDA, CHIYUKI, FUKUHARA, AKIKO, NAGAI, HIROKI, KIM, YOUNG HAK, MISHIMA, MICHIAKI
Publicado 2013

Melanoma Transition Is Frequently Accompanied by a Loss of Cytoglobin Expression in Melanocytes: A Novel Expression Site of Cytoglobin

por Fujita, Yoshihiko, Koinuma, Satoshi, De Velasco, Marco A., Bolz, Jan, Togashi, Yosuke, Terashima, Masato, Hayashi, Hidetoshi, Matsuo, Takuya, Nishio, Kazuto
Publicado 2014

Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8(+) T cells in the tumor microenvironment

por Tada, Yasuko, Togashi, Yosuke, Kotani, Daisuke, Kuwata, Takeshi, Sato, Eichi, Kawazoe, Akihito, Doi, Toshihiko, Wada, Hisashi, Nishikawa, Hiroyoshi, Shitara, Kohei
Publicado 2018

HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs

por Watanabe, Sho, Goto, Yasushi, Yasuda, Hiroyuki, Kohno, Takashi, Motoi, Noriko, Ohe, Yuichiro, Nishikawa, Hiroyoshi, Kobayashi, Susumu S., Kuwano, Kazuyoshi, Togashi, Yosuke
Publicado 2021

Selective inhibition of low-affinity memory CD8(+) T cells by corticosteroids

por Tokunaga, Akihiro, Sugiyama, Daisuke, Maeda, Yuka, Warner, Allison Betof, Panageas, Katherine S., Ito, Sachiko, Togashi, Yosuke, Sakai, Chika, Wolchok, Jedd D., Nishikawa, Hiroyoshi
Publicado 2019

Efficacy of increased-dose erlotinib for central nervous system metastases in non-small cell lung cancer patients with epidermal growth factor receptor mutation

por Togashi, Yosuke, Masago, Katsuhiro, Fukudo, Masahide, Tsuchido, Yasuhiro, Okuda, Chiyuki, Kim, Young Hak, Ikemi, Yasuaki, Sakamori, Yuichi, Mio, Tadashi, Katsura, Toshiya, Mishima, Michiaki
Publicado 2011

Somatic mutations can induce a noninflamed tumour microenvironment via their original gene functions, despite deriving neoantigens

por Ishino, Takamasa, Kawashima, Shusuke, Tanji, Etsuko, Ueno, Toshihide, Ueda, Youki, Ogasawara, Sadahisa, Sato, Kazuhito, Mano, Hiroyuki, Ishihara, Soichiro, Kato, Naoya, Kawazu, Masahito, Togashi, Yosuke
Publicado 2023

Good Clinical Response to Erlotinib in a Non-Small Cell Lung Cancer Patient Harboring Multiple Brain Metastases and a Double Active Somatic Epidermal Growth Factor Gene Mutation

por Masago, Katsuhiro, Togashi, Yosuke, Fukudo, Masahide, Terada, Tomohiro, Irisa, Kaoru, Sakamori, Yuichi, Fujita, Shiro, Kim, Young Hak, Mio, Tadashi, Inui, Ken-ichi, Mishima, Michiaki
Publicado 2010

Outcome of Surgical Treatment for Metastatic Vertebra Bone Tumor in Advanced Lung Cancer

por Fukuhara, Akiko, Masago, Katsuhiro, Neo, Masashi, Fujibayashi, Shunsuke, Fujita, Shiro, Hatachi, Yukimasa, Irisa, Kaoru, Sakamori, Yuichi, Togashi, Yosuke, Kim, Young Hak, Mio, Tadashi, Mishima, Michiaki
Publicado 2010

Immunologic Significance of CD80/CD86 or Major Histocompatibility Complex-II Expression in Thymic Epithelial Tumors

por Ikeda, Hideki, Nagasaki, Joji, Shimizu, Daiki, Katsuya, Yuki, Horinouchi, Hidehito, Hosomi, Yukio, Tanji, Etsuko, Iwata, Takekazu, Itami, Makiko, Kawazu, Masahito, Ohe, Yuichiro, Suzuki, Takuji, Togashi, Yosuke
Publicado 2023

Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production

por Togashi, Yosuke, Arao, Tokuzo, Kato, Hiroaki, Matsumoto, Kazuko, Terashima, Masato, Hayashi, Hidetoshi, de Velasco, Marco A, Fujita, Yoshihiko, Kimura, Hideharu, Yasuda, Takushi, Shiozaki, Hitoshi, Nishio, Kazuto
Publicado 2013

Performance of a novel KRAS mutation assay for formalin-fixed paraffin embedded tissues of colorectal cancer

por Sakai, Kazuko, Yoneshige, Azusa, Ito, Akihiko, Ueda, Yoji, Kondo, Satoshi, Nobumasa, Hitoshi, Fujita, Yoshihiko, Togashi, Yosuke, Terashima, Masato, De Velasco, Marco A, Tomida, Shuta, Nishio, Kazuto
Publicado 2015