Broadly neutralizing antibodies: What is needed to move from a rare event in HIV-1 infection to vaccine efficacy?

por Subbaraman, Harini, Schanz, Merle, Trkola, Alexandra
Publicado 2018

OMIP‐047: High‐Dimensional phenotypic characterization of B cells

por Liechti, Thomas, Günthard, Huldrych F., Trkola, Alexandra
Publicado 2018

CD4 occupancy triggers sequential pre-fusion conformational states of the HIV-1 envelope trimer with relevance for broadly neutralizing antibody activity

por Ivan, Branislav, Sun, Zhaozhi, Subbaraman, Harini, Friedrich, Nikolas, Trkola, Alexandra
Publicado 2019

Immune Senescence: Relative Contributions of Age and Cytomegalovirus Infection

por Mekker, Andrea, Tchang, Vincent S., Haeberli, Lea, Oxenius, Annette, Trkola, Alexandra, Karrer, Urs
Publicado 2012

Different Infectivity of HIV-1 Strains Is Linked to Number of Envelope Trimers Required for Entry

por Brandenberg, Oliver F., Magnus, Carsten, Rusert, Peter, Regoes, Roland R., Trkola, Alexandra
Publicado 2015

Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent

por Reh, Lucia, Magnus, Carsten, Schanz, Merle, Weber, Jacqueline, Uhr, Therese, Rusert, Peter, Trkola, Alexandra
Publicado 2015

Influence of time to diagnosis of severe influenza on antibiotic use, length of stay, isolation precautions, and mortality: a retrospective study

por Akers, Isabel E., Weber, Rainer, Sax, Hugo, Böni, Jürg, Trkola, Alexandra, Kuster, Stefan P.
Publicado 2017

Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters

por Brandenberg, Oliver F., Magnus, Carsten, Rusert, Peter, Günthard, Huldrych F., Regoes, Roland R., Trkola, Alexandra
Publicado 2017

Cell-Cell Transmission Enables HIV-1 to Evade Inhibition by Potent CD4bs Directed Antibodies

por Abela, Irene A., Berlinger, Livia, Schanz, Merle, Reynell, Lucy, Günthard, Huldrych F., Rusert, Peter, Trkola, Alexandra
Publicado 2012

High-Throughput Sequencing of Human Immunoglobulin Variable Regions with Subtype Identification

por Schanz, Merle, Liechti, Thomas, Zagordi, Osvaldo, Miho, Enkelejda, Reddy, Sai T., Günthard, Huldrych F., Trkola, Alexandra, Huber, Michael
Publicado 2014

Widespread B cell perturbations in HIV-1 infection afflict naive and marginal zone B cells

por Liechti, Thomas, Kadelka, Claus, Braun, Dominique L., Kuster, Herbert, Böni, Jürg, Robbiani, Melissa, Günthard, Huldrych F., Trkola, Alexandra
Publicado 2019

Antiviral Activity of Type I, II, and III Interferons Counterbalances ACE2 Inducibility and Restricts SARS-CoV-2

por Busnadiego, Idoia, Fernbach, Sonja, Pohl, Marie O., Karakus, Umut, Huber, Michael, Trkola, Alexandra, Stertz, Silke, Hale, Benjamin G.
Publicado 2020

Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center

por Scheier, Thomas, Shah, Cyril, Huber, Michael, Sax, Hugo, Hasse, Barbara, Günthard, Huldrych F., Trkola, Alexandra, Schreiber, Peter W.
Publicado 2021

In Vivo Binding and Retention of CD4-Specific DARPin 57.2 in Macaques

por Pugach, Pavel, Krarup, Anders, Gettie, Agegnehu, Kuroda, Marcelo, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Trkola, Alexandra, Robbiani, Melissa
Publicado 2010

HIV-1 replication activates CD4(+) T cells with specificities for persistent herpes viruses

por Haas, Anna, Rehr, Manuela, Graw, Frederik, Rusert, Peter, Bossart, Walter, Kuster, Herbert, Trkola, Alexandra, Günthard, Huldrych F, Oxenius, Annette
Publicado 2010

Partial rescue of V1V2 mutant infectivity by HIV-1 cell-cell transmission supports the domain’s exceptional capacity for sequence variation

por Brandenberg, Oliver F, Rusert, Peter, Magnus, Carsten, Weber, Jacqueline, Böni, Jürg, Günthard, Huldrych F, Regoes, Roland R, Trkola, Alexandra
Publicado 2014

Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage

por Reh, Lucia, Magnus, Carsten, Kadelka, Claus, Kühnert, Denise, Uhr, Therese, Weber, Jacqueline, Morris, Lynn, Moore, Penny L., Trkola, Alexandra
Publicado 2018

Reply to correspondence ‘Conserved signatures indicate HIV-1 transmission is under strong selection and thus is not a “stochastic” process’ by Gonzalez et al., Retrovirology 2017...

por Oberle, Corinna S., Magnus, Carsten, Joos, Beda, Rusert, Peter, Beauparlant, David, Kouyos, Roger, Trkola, Alexandra, Metzner, Karin J., Günthard, Huldrych F.
Publicado 2017

Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

por Lewandowska, Dagmara W., Zagordi, Osvaldo, Geissberger, Fabienne-Desirée, Kufner, Verena, Schmutz, Stefan, Böni, Jürg, Metzner, Karin J., Trkola, Alexandra, Huber, Michael
Publicado 2017

Correction to: Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

por Lewandowska, Dagmara W., Zagordi, Osvaldo, Geissberger, Fabienne-Desirée, Kufner, Verena, Schmutz, Stefan, Böni, Jürg, Metzner, Karin J., Trkola, Alexandra, Huber, Michael
Publicado 2017