The NLRP1 and CARD8 inflammasomes

por Taabazuing, Cornelius Y., Griswold, Andrew R., Bachovchin, Daniel A.
Publicado 2020

DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation

por Griswold, Andrew R., Ball, Daniel P., Bhattacharjee, Abir, Chui, Ashley J., Rao, Sahana D., Taabazuing, Cornelius Y., Bachovchin, Daniel A.
Publicado 2019

Activation of the CARD8 Inflammasome Requires a Disordered Region

por Chui, Ashley J., Griswold, Andrew R., Taabazuing, Cornelius Y., Orth, Elizabeth L., Gai, Kuo, Rao, Sahana D., Ball, Daniel P., Hsiao, Jeffrey C., Bachovchin, Daniel A.
Publicado 2020

The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases

por Exconde, Patrick M., Hernandez-Chavez, Claudia, Bray, Mark B., Lopez, Jan L., Srivastava, Tamanna, Egan, Marisa S., Zhang, Jenna, Shin, Sunny, Discher, Bohdana M., Taabazuing, Cornelius Y.
Publicado 2023

Caspase-1 interdomain linker cleavage is required for pyroptosis

por Ball, Daniel P, Taabazuing, Cornelius Y, Griswold, Andrew R, Orth, Elizabeth L, Rao, Sahana D, Kotliar, Ilana B, Vostal, Lauren E, Johnson, Darren C, Bachovchin, Daniel A
Publicado 2020

DPP8/9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia

por Johnson, Darren C., Taabazuing, Cornelius Y., Okondo, Marian C., Chui, Ashley J., Rao, Sahana D., Brown, Fiona C., Reed, Casie, Peguero, Elizabeth, de Stanchina, Elisa, Kentsis, Alex, Bachovchin, Daniel A.
Publicado 2018

A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome

por Hsiao, Jeffrey C., Neugroschl, Atara R., Chui, Ashley J., Taabazuing, Cornelius Y., Griswold, Andrew R., Wang, Qinghui, Huang, Hsin-Che, Orth-He, Elizabeth L., Ball, Daniel P., Hiotis, Giorgos, Bachovchin, Daniel A.
Publicado 2022