Remodelling of the Mitochondrial Bioenergetic Pathways in Human Cultured Fibroblasts with Carbohydrates

por Protasoni, Margherita, Taanman, Jan-Willem
Publicado 2023

Clonal Expansion of T Cells in Abdominal Aortic Aneurysm: A Role for Doxycycline as Drug of Choice?

por Kroon, Albert M., Taanman, Jan-Willem
Publicado 2015

Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3

por Protasoni, Margherita, Kroon, Albert M., Taanman, Jan-Willem
Publicado 2018

A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria

por Pryde, Kenneth Robert, Taanman, Jan Willem, Schapira, Anthony Henry
Publicado 2016

Lowering the apoptotic threshold in colorectal cancer cells by targeting mitochondria

por Sagar, Jayesh, Sales, Kevin, Taanman, Jan-Willem, Dijk, Sas, Winslet, Marc
Publicado 2010

Ambroxol reverses tau and α-synuclein accumulation in a cholinergic N370S GBA1 mutation model

por Yang, Shi Yu, Taanman, Jan-Willem, Gegg, Matthew, Schapira, Anthony H V
Publicado 2022

Does Doxycycline work in synergy with cisplatin and oxaliplatin in colorectal cancer?

por Sagar, Jayesh, Sales, Kevin, Dijk, Sas, Taanman, JanWillem, Seifalian, Alexander, Winslet, Mark
Publicado 2009

Silencing of PINK1 Expression Affects Mitochondrial DNA and Oxidative Phosphorylation in DOPAMINERGIC Cells

por Gegg, Matthew E., Cooper, J. Mark, Schapira, Anthony H. V., Taanman, Jan-Willem
Publicado 2009

Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine

por Dijk, Sas N., Protasoni, Margherita, Elpidorou, Marilena, Kroon, Albert M., Taanman, Jan-Willem
Publicado 2020

Mitochondrial respiratory chain and Krebs cycle enzyme function in human donor livers subjected to end-ischaemic hypothermic machine perfusion

por Abudhaise, Hamid, Taanman, Jan-Willem, DeMuylder, Peter, Fuller, Barry, Davidson, Brian R.
Publicado 2021

A Human Neural Crest Stem Cell-Derived Dopaminergic Neuronal Model Recapitulates Biochemical Abnormalities in GBA1 Mutation Carriers

por Yang, Shi-Yu, Beavan, Michelle, Chau, Kai-Yin, Taanman, Jan-Willem, Schapira, Anthony H.V.
Publicado 2017

The PINK1—Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells

por Bradshaw, Aaron V., Campbell, Philip, Schapira, Anthony H. V., Morris, Huw R., Taanman, Jan-Willem
Publicado 2021

Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells

por Haschler, Timo N., Horsley, Harry, Balys, Monika, Anderson, Glenn, Taanman, Jan-Willem, Unwin, Robert J., Norman, Jill T.
Publicado 2021

The diagnosis of inherited metabolic diseases by microarray gene expression profiling

por Arenas Hernandez, Monica, Schulz, Reiner, Chaplin, Tracy, Young, Bryan D, Perrett, David, Champion, Michael P, Taanman, Jan-Willem, Fensom, Anthony, Marinaki, Anthony M
Publicado 2010

DNA isolation protocol effects on nuclear DNA analysis by microarrays, droplet digital PCR, and whole genome sequencing, and on mitochondrial DNA copy number estimation

por Nacheva, Elizabeth, Mokretar, Katya, Soenmez, Aynur, Pittman, Alan M., Grace, Colin, Valli, Roberto, Ejaz, Ayesha, Vattathil, Selina, Maserati, Emanuela, Houlden, Henry, Taanman, Jan-Willem, Schapira, Anthony H., Proukakis, Christos
Publicado 2017

HIBCH mutations can cause Leigh-like disease with combined deficiency of multiple mitochondrial respiratory chain enzymes and pyruvate dehydrogenase

por Ferdinandusse, Sacha, Waterham, Hans R, Heales, Simon JR, Brown, Garry K, Hargreaves, Iain P, Taanman, Jan-Willem, Gunny, Roxana, Abulhoul, Lara, Wanders, Ronald JA, Clayton, Peter T, Leonard, James V, Rahman, Shamima
Publicado 2013

A Clinical, Neuropathological and Genetic Study of Homozygous A467T POLG-Related Mitochondrial Disease

por Rajakulendran, Sanjeev, Pitceathly, Robert D. S., Taanman, Jan-Willem, Costello, Harry, Sweeney, Mary G., Woodward, Cathy E., Jaunmuktane, Zane, Holton, Janice L., Jacques, Thomas S., Harding, Brian N., Fratter, Carl, Hanna, Michael G., Rahman, Shamima
Publicado 2016

Exploring metabolism in scleroderma reveals opportunities for pharmacological intervention for therapy in fibrosis

por Cantanhede, Isabella Gomes, Liu, Huan, Liu, Huan, Balbuena Rodriguez, Vestaen, Shiwen, Xu, Ong, Voo H., Denton, Christopher P., Ponticos, Markella, Xiong, Guo, Lima-Filho, José Luiz, Abraham, David, Abu-Hanna, Jeries, Taanman, Jan-Willem
Publicado 2022

TRNT1 deficiency: clinical, biochemical and molecular genetic features

por Wedatilake, Yehani, Niazi, Rojeen, Fassone, Elisa, Powell, Christopher A., Pearce, Sarah, Plagnol, Vincent, Saldanha, José W., Kleta, Robert, Chong, W Kling, Footitt, Emma, Mills, Philippa B., Taanman, Jan-Willem, Minczuk, Michal, Clayton, Peter T., Rahman, Shamima
Publicado 2016

Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission

por Shahni, Rojeen, Cale, Catherine M., Anderson, Glenn, Osellame, Laura D., Hambleton, Sophie, Jacques, Thomas S., Wedatilake, Yehani, Taanman, Jan-Willem, Chan, Emma, Qasim, Waseem, Plagnol, Vincent, Chalasani, Annapurna, Duchen, Michael R., Gilmour, Kimberly C., Rahman, Shamima
Publicado 2015