Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells

por Ceccarello, Erica, Tabaglio, Tommaso, Koh, Sarene, Oei, Vincent, Teo, Winnie, Jonathan, Owen Julianto, Pavesi, Andrea, Chen, Qingfeng, Bertoletti, Antonio, Wee, Keng Boon, Guccione, Ernesto
Publicado 2021

MBNL1 alternative splicing isoforms play opposing roles in cancer

por Tabaglio, Tommaso, Low, Diana HP, Teo, Winnie Koon Lay, Goy, Pierre Alexis, Cywoniuk, Piotr, Wollmann, Heike, Ho, Jessica, Tan, Damien, Aw, Joey, Pavesi, Andrea, Sobczak, Krzysztof, Wee, Dave Keng Boon, Guccione, Ernesto
Publicado 2018

G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma

por Lam, Maxine S. Y., Reales-Calderon, Jose Antonio, Ow, Jin Rong, Aw, Joey J. Y., Tan, Damien, Vijayakumar, Ragavi, Ceccarello, Erica, Tabaglio, Tommaso, Lim, Yan Ting, Chien, Wang Loo, Lai, Fritz, Tanoto, Anthony Tan, Chen, Qingfeng, Sobota, Radoslaw M., Adriani, Giulia, Bertoletti, Antonio, Guccione, Ernesto, Pavesi, Andrea
Publicado 2023

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness

por Ho, Jessica SY, Di Tullio, Federico, Schwarz, Megan, Low, Diana, Incarnato, Danny, Gay, Florence, Tabaglio, Tommaso, Zhang, JingXian, Wollmann, Heike, Chen, Leilei, An, Omer, Chan, Tim Hon Man, Hall Hickman, Alexander, Zheng, Simin, Roudko, Vladimir, Chen, Sujun, Karz, Alcida, Ahmed, Musaddeque, He, Housheng Hansen, Greenbaum, Benjamin D, Oliviero, Salvatore, Serresi, Michela, Gargiulo, Gaetano, Mann, Karen M, Hernando, Eva, Mulholland, David, Marazzi, Ivan, Wee, Dave Keng Boon, Guccione, Ernesto
Publicado 2021