Is it time to rethink the Alzheimer's disease drug development strategy by targeting its silent phase?

por Souchet, Benoit, Audrain, Mickael, Billoir, Baptiste, Lecanu, Laurent, Tada, Satoru, Braudeau, Jérôme
Publicado 2018

Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis

por Tada, Satoru, Okuno, Tatsusada, Yasui, Teruhito, Nakatsuji, Yuji, Sugimoto, Tomoyuki, Kikutani, Hitoshi, Sakoda, Saburo
Publicado 2011

BAFF Controls Neural Cell Survival through BAFF Receptor

por Tada, Satoru, Yasui, Teruhito, Nakatsuji, Yuji, Okuno, Tatsusada, Koda, Toru, Mochizuki, Hideki, Sakoda, Saburo, Kikutani, Hitoshi
Publicado 2013

A Mild Clinical Phenotype with Myopathic and Hemolytic Forms of Phosphoglycerate Kinase Deficiency (PGK Osaka): A Case Report and Literature Review

por Baba, Kousuke, Fukuda, Tokiko, Furuta, Mitsuru, Tada, Satoru, Imai, Atsuko, Asano, Yoshihiro, Sugie, Hideo, P. Takahashi, Masanori, Mochizuki, Hideki
Publicado 2022

Severe parkinsonism associated with anti-CRMP5 antibody-positive paraneoplastic neurological syndrome and abnormal signal intensity in the bilateral basal ganglia

por Tada, Satoru, Furuta, Mitsuru, Fukada, Kei, Hirozawa, Daisuke, Matsui, Misa, Aoike, Futoshi, Okuno, Tatsusada, Sawada, Jin-ichi, Mochizuki, Hideki, Hazama, Takanori
Publicado 2016

Xanthine Oxidase Mediates Axonal and Myelin Loss in a Murine Model of Multiple Sclerosis

por Honorat, Josephe Archie, Kinoshita, Makoto, Okuno, Tatsusada, Takata, Kazushiro, Koda, Toru, Tada, Satoru, Shirakura, Takashi, Fujimura, Harutoshi, Mochizuki, Hideki, Sakoda, Saburo, Nakatsuji, Yuji
Publicado 2013

Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain

por Orefice, Nicola Salvatore, Souchet, Benoît, Braudeau, Jérôme, Alves, Sandro, Piguet, Françoise, Collaud, Fanny, Ronzitti, Giuseppe, Tada, Satoru, Hantraye, Philippe, Mingozzi, Federico, Ducongé, Frédéric, Cartier, Nathalie
Publicado 2019

Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder

por Murata, Hisashi, Kinoshita, Makoto, Yasumizu, Yoshiaki, Motooka, Daisuke, Beppu, Shohei, Shiraishi, Naoyuki, Sugiyama, Yasuko, Kihara, Keigo, Tada, Satoru, Koda, Toru, Konaka, Hachiro, Takamatsu, Hyota, Kumanogoh, Atsushi, Okuno, Tatsusada, Mochizuki, Hideki
Publicado 2022

Partial suppression of M1 microglia by Janus kinase 2 inhibitor does not protect against neurodegeneration in animal models of amyotrophic lateral sclerosis

por Tada, Satoru, Okuno, Tatsusada, Hitoshi, Yasumichi, Yasui, Teruhito, Honorat, Josephe Archie, Takata, Kazushiro, Koda, Toru, Shimagami, Hiroshi, Chi-Jing, Choong, Namba, Akiko, Sugimoto, Tomoyuki, Sakoda, Saburo, Mochizuki, Hideki, Kikutani, Hitoshi, Nakatsuji, Yuji
Publicado 2014

Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase

por Koda, Toru, Namba, Akiko, Kinoshita, Makoto, Nakatsuji, Yuji, Sugimoto, Tomoyuki, Sakakibara, Kaori, Tada, Satoru, Shimizu, Mikito, Yamashita, Kazuya, Takata, Kazushiro, Ishikura, Teruyuki, Murata, Syo, Beppu, Shohei, Kumanogoh, Atsushi, Mochizuki, Hideki, Okuno, Tatsusada
Publicado 2020

Genetically modified macrophages accelerate myelin repair

por Aigrot, Marie‐Stéphane, Barthelemy, Clara, Moyon, Sarah, Dufayet‐Chaffaud, Gaelle, Izagirre‐Urizar, Leire, Gillet‐Legrand, Beatrix, Tada, Satoru, Bayón‐Cordero, Laura, Chara, Juan‐Carlos, Matute, Carlos, Cartier, Nathalie, Lubetzki, Catherine, Tepavčević, Vanja
Publicado 2022

Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis

por Tada, Satoru, Okuno, Tatsusada, Shimizu, Mikito, Sakai, Yoshiki, Sumi-Akamaru, Hisae, Kinoshita, Makoto, Yamashita, Kazuya, Sanda, Eri, Choong, Chi-Jing, Namba, Akiko, Sasaki, Tsutomu, Koda, Toru, Takata, Kazushiro, Miyagawa, Shigeru, Sawa, Yoshiki, Nakatsuji, Yuji, Mochizuki, Hideki
Publicado 2019

High cell surface expression and peptide binding affinity of HLA-DQA1*05:03, a susceptible allele of neuromyelitis optica spectrum disorders (NMOSD)

por Beppu, Shohei, Kinoshita, Makoto, Wilamowski, Jan, Suenaga, Tadahiro, Yasumizu, Yoshiaki, Ogawa, Kotaro, Ishikura, Teruyuki, Tada, Satoru, Koda, Toru, Murata, Hisashi, Shiraishi, Naoyuki, Sugiyama, Yasuko, Kihara, Keigo, Sugimoto, Tomoyuki, Arase, Hisashi, Standley, Daron M., Okuno, Tatsusada, Mochizuki, Hideki
Publicado 2022

Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

por Souchet, Benoît, Audrain, Mickael, Billard, Jean Marie, Dairou, Julien, Fol, Romain, Orefice, Nicola Salvatore, Tada, Satoru, Gu, Yuchen, Dufayet-Chaffaud, Gaelle, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Alves, Sandro, Meijer, Laurent, Janel, Nathalie, Braudeau, Jérôme, Cartier, Nathalie
Publicado 2019

Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation

por Shimizu, Mikito, Okuno, Tatsusada, Kinoshita, Makoto, Sumi, Hisae, Fujimura, Harutoshi, Yamashita, Kazuya, Sugimoto, Tomoyuki, Sakakibara, Shuhei, Sakakibara, Kaori, Koda, Toru, Tada, Satoru, Ishikura, Teruyuki, Murata, Hisashi, Beppu, Shohei, Shiraishi, Naoyuki, Sugiyama, Yasuko, Nakatsuji, Yuji, Kumanogoh, Atsushi, Mochizuki, Hideki
Publicado 2020

Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats

por Ishikura, Teruyuki, Kinoshita, Makoto, Shimizu, Mikito, Yasumizu, Yoshiaki, Motooka, Daisuke, Okuzaki, Daisuke, Yamashita, Kazuya, Murata, Hisashi, Beppu, Shohei, Koda, Toru, Tada, Satoru, Shiraishi, Naoyuki, Sugiyama, Yasuko, Miyamoto, Katsuichi, Kusunoki, Susumu, Sugimoto, Tomoyuki, Kumanogoh, Atsushi, Okuno, Tatsusada, Mochizuki, Hideki
Publicado 2021

RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS

por Shimizu, Mikito, Shiraishi, Naoyuki, Tada, Satoru, Sasaki, Tsutomu, Beck, Goichi, Nagano, Seiichi, Kinoshita, Makoto, Sumi, Hisae, Sugimoto, Tomoyuki, Ishida, Yoko, Koda, Toru, Ishikura, Teruyuki, Sugiyama, Yasuko, Kihara, Keigo, Kanakura, Minami, Nakajima, Tsuneo, Takeda, Shuko, Takahashi, Masanori P., Yamashita, Toshihide, Okuno, Tatsusada, Mochizuki, Hideki
Publicado 2023

Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma

por Yasumizu, Yoshiaki, Ohkura, Naganari, Murata, Hisashi, Kinoshita, Makoto, Funaki, Soichiro, Nojima, Satoshi, Kido, Kansuke, Kohara, Masaharu, Motooka, Daisuke, Okuzaki, Daisuke, Suganami, Shuji, Takeuchi, Eriko, Nakamura, Yamami, Takeshima, Yusuke, Arai, Masaya, Tada, Satoru, Okumura, Meinoshin, Morii, Eiichi, Shintani, Yasushi, Sakaguchi, Shimon, Okuno, Tatsusada, Mochizuki, Hideki
Publicado 2022