Type I IFN is siloed in endosomes

por Altman, Jennie B., Taft, Justin, Wedeking, Tim, Gruber, Conor N., Holtmannspötter, Michael, Piehler, Jacob, Bogunovic, Dusan
Publicado 2020

Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing

por Park, Arnold, Hong, Patrick, Won, Sohui T, Thibault, Patricia A, Vigant, Frederic, Oguntuyo, Kasopefoluwa Y, Taft, Justin D, Lee, Benhur
Publicado 2016

CARDIOMYOPATHIC GENE MUTATIONS ALTER ACE2 EXPRESSION AND INFECTIVITY OF SARS-COV-2 IN HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES

por Kontorovich, Amy, Ng, Simon, Hain, Elizabeth, Taft, Justin, Rodriguez, Nelson, Nitzl, Angelika, Koenig, Andreas, Bogunovic, Dusan, Gelb, Bruce, Koenig, Iwona
Publicado 2021

Homozygous STAT2 gain-of-function mutation by loss of USP18 activity in a patient with type I interferonopathy

por Gruber, Conor, Martin-Fernandez, Marta, Ailal, Fatima, Qiu, Xueer, Taft, Justin, Altman, Jennie, Rosain, Jérémie, Buta, Sofija, Bousfiha, Aziz, Casanova, Jean-Laurent, Bustamante, Jacinta, Bogunovic, Dusan
Publicado 2020

ISG15 deficiency restricts HIV-1 infection

por Jurczyszak, Denise, Manganaro, Lara, Buta, Sofija, Gruber, Conor, Martin-Fernandez, Marta, Taft, Justin, Patel, Roosheel S., Cipolla, Melissa, Alshammary, Hala, Mulder, Lubbertus C. F., Sachidanandam, Ravi, Bogunovic, Dusan, Simon, Viviana
Publicado 2022

An ACE2 Triple Decoy that neutralizes SARS-CoV-2 shows enhanced affinity for virus variants

por Tanaka, Shiho, Nelson, Gard, Olson, C. Anders, Buzko, Oleksandr, Higashide, Wendy, Shin, Annie, Gonzalez, Marcos, Taft, Justin, Patel, Roosheel, Buta, Sofija, Richardson, Ashley, Bogunovic, Dusan, Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Publicado 2021

Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display

por Tanaka, Shiho, Olson, C. Anders, Barnes, Christopher O., Higashide, Wendy, Gonzalez, Marcos, Taft, Justin, Richardson, Ashley, Martin-Fernandez, Marta, Bogunovic, Dusan, Gnanapragasam, Priyanthi N.P., Bjorkman, Pamela J., Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Publicado 2022

Autoimmunity in Down’s syndrome via cytokines, CD4 T cells and CD11c(+) B cells

por Malle, Louise, Patel, Roosheel S., Martin-Fernandez, Marta, Stewart, O Jay, Philippot, Quentin, Buta, Sofija, Richardson, Ashley, Barcessat, Vanessa, Taft, Justin, Bastard, Paul, Samuels, Julie, Mircher, Clotilde, Rebillat, Anne-Sophie, Maillebouis, Louise, Vilaire-Meunier, Marie, Tuballes, Kevin, Rosenberg, Brad R., Trachtman, Rebecca, Casanova, Jean-Laurent, Notarangelo, Luigi D., Gnjatic, Sacha, Bush, Douglas, Bogunovic, Dusan
Publicado 2023

A partial form of inherited human USP18 deficiency underlies infection and inflammation

por Martin-Fernandez, Marta, Buta, Sofija, Le Voyer, Tom, Li, Zhi, Dynesen, Lasse Toftdal, Vuillier, Françoise, Franklin, Lina, Ailal, Fatima, Muglia Amancio, Alice, Malle, Louise, Gruber, Conor, Benhsaien, Ibtihal, Altman, Jennie, Taft, Justin, Deswarte, Caroline, Roynard, Manon, Nieto-Patlan, Alejandro, Moriya, Kunihiko, Rosain, Jérémie, Boddaert, Nathalie, Bousfiha, Aziz, Crow, Yanick J., Jankovic, Dragana, Sher, Alan, Casanova, Jean-Laurent, Pellegrini, Sandra, Bustamante, Jacinta, Bogunovic, Dusan
Publicado 2022

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

por Cottrell, Christopher A., Manne, Kartik, Kong, Rui, Wang, Shuishu, Zhou, Tongqing, Chuang, Gwo-Yu, Edwards, Robert J., Henderson, Rory, Janowska, Katarzyna, Kopp, Megan, Lin, Bob C., Louder, Mark K., Olia, Adam S., Rawi, Reda, Shen, Chen-Hsiang, Taft, Justin D., Torres, Jonathan L., Wu, Nelson R., Zhang, Baoshan, Doria-Rose, Nicole A., Cohen, Myron S., Haynes, Barton F., Shapiro, Lawrence, Ward, Andrew B., Acharya, Priyamvada, Mascola, John R., Kwong, Peter D.
Publicado 2021