Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency

por Strubbe, Steven, Taghon, Tom
Publicado 2021

T-ALL and thymocytes: a message of noncoding RNAs

por Wallaert, Annelynn, Durinck, Kaat, Taghon, Tom, Van Vlierberghe, Pieter, Speleman, Frank
Publicado 2017

Conventional and Computational Flow Cytometry Analyses Reveal Sustained Human Intrathymic T Cell Development From Birth Until Puberty

por Lavaert, Marieke, Valcke, Brecht, Vandekerckhove, Bart, Leclercq, Georges, Liang, Kai Ling, Taghon, Tom
Publicado 2020

Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing

por Wallaert, Annelynn, Van Loocke, Wouter, Hernandez, Lucie, Taghon, Tom, Speleman, Frank, Van Vlierberghe, Pieter
Publicado 2017

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

por Kiekens, Laura, Wahlen, Sigrid, Persyn, Eva, De Vos, Zenzi, Taghon, Tom, Vandekerckhove, Bart, Leclercq, Georges
Publicado 2022

Quantification of Reverse Transcriptase Activity by Real-Time PCR as a Fast and Accurate Method for Titration of HIV, Lenti- and Retroviral Vectors

por Vermeire, Jolien, Naessens, Evelien, Vanderstraeten, Hanne, Landi, Alessia, Iannucci, Veronica, Van Nuffel, Anouk, Taghon, Tom, Pizzato, Massimo, Verhasselt, Bruno
Publicado 2012

T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources

por Bonte, Sarah, De Munter, Stijn, Goetgeluk, Glenn, Ingels, Joline, Pille, Melissa, Billiet, Lore, Taghon, Tom, Leclercq, Georges, Vandekerckhove, Bart, Kerre, Tessa
Publicado 2020

hsa-miR-20b-5p and hsa-miR-363-3p Affect Expression of PTEN and BIM Tumor Suppressor Genes and Modulate Survival of T-ALL Cells In Vitro

por Drobna, Monika, Szarzyńska, Bronisława, Jaksik, Roman, Sędek, Łukasz, Kuchmiy, Anna, Taghon, Tom, Van Vlierberghe, Pieter, Szczepański, Tomasz, Witt, Michał, Dawidowska, Małgorzata
Publicado 2020

HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development

por De Decker, Matthias, Lavaert, Marieke, Roels, Juliette, Tilleman, Laurentijn, Vandekerckhove, Bart, Leclercq, Georges, Van Nieuwerburgh, Filip, Van Vlierberghe, Pieter, Taghon, Tom
Publicado 2020

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

por Roels, Juliette, Van Hulle, Jolien, Lavaert, Marieke, Kuchmiy, Anna, Strubbe, Steven, Putteman, Tom, Vandekerckhove, Bart, Leclercq, Georges, Van Nieuwerburgh, Filip, Boehme, Lena, Taghon, Tom
Publicado 2022

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours

por Filtjens, Jessica, Keirsse, Jiri, Van Ammel, Els, Taveirne, Sylvie, Van Acker, Aline, Kerre, Tessa, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, Van Ginderachter, Jo A., Leclercq, Georges
Publicado 2016

A Novel Non-Coding Variant in DCLRE1C Results in Deregulated Splicing and Induces SCID Through the Generation of a Truncated ARTEMIS Protein That Fails to Support V(D)J Recombinati...

por Strubbe, Steven, De Bruyne, Marieke, Pannicke, Ulrich, Beyls, Elien, Vandekerckhove, Bart, Leclercq, Georges, De Baere, Elfride, Bordon, Victoria, Vral, Anne, Schwarz, Klaus, Haerynck, Filomeen, Taghon, Tom
Publicado 2021

TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality

por Persyn, Eva, Wahlen, Sigrid, Kiekens, Laura, Taveirne, Sylvie, Van Loocke, Wouter, Van Ammel, Els, Van Nieuwerburgh, Filip, Taghon, Tom, Vandekerckhove, Bart, Van Vlierberghe, Pieter, Leclercq, Georges
Publicado 2022

Ly49E Expression on CD8αα-Expressing Intestinal Intraepithelial Lymphocytes Plays No Detectable Role in the Development and Progression of Experimentally Induced Inflammatory Bowel...

por Van Acker, Aline, Filtjens, Jessica, Van Welden, Sophie, Taveirne, Sylvie, Van Ammel, Els, Vanhees, Mandy, Devisscher, Lindsey, Kerre, Tessa, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, Leclercq, Georges
Publicado 2014

Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T‐ALL: Focus on miR‐363‐3p and promoter methylation

por Drobna‐Śledzińska, Monika, Maćkowska‐Maślak, Natalia, Jaksik, Roman, Kosmalska, Maria, Szarzyńska, Bronisława, Lejman, Monika, Sędek, Łukasz, Szczepański, Tomasz, Taghon, Tom, Van Vlierberghe, Pieter, Witt, Michał, Dawidowska, Małgorzata
Publicado 2022

The Ly49E Receptor Inhibits the Immune Control of Acute Trypanosoma cruzi Infection

por Filtjens, Jessica, Coltel, Nicolas, Cencig, Sabrina, Taveirne, Sylvie, Van Ammel, Els, Van Acker, Aline, Kerre, Tessa, Matthys, Patrick, Taghon, Tom, Vandekerckhove, Bart, Carlier, Yves, Truyens, Carine, Leclercq, Georges
Publicado 2016

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced...

por Bonte, Sarah, de Munter, Stijn, Billiet, Lore, Goetgeluk, Glenn, Ingels, Joline, Jansen, Hanne, Pille, Melissa, de Cock, Laurenz, Weening, Karin, Taghon, Tom, Leclercq, Georges, Vandekerckhove, Bart, Kerre, Tessa
Publicado 2021

Contribution of the Ly49E Natural Killer Receptor in the Immune Response to Plasmodium berghei Infection and Control of Hepatic Parasite Development

por Filtjens, Jessica, Foquet, Lander, Taveirne, Sylvie, Van Ammel, Els, Vanhees, Mandy, Van Acker, Aline, Kerre, Tessa, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, Van den Steen, Philippe E., Leclercq, Georges
Publicado 2014

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20

por Drennan, Michael B., Govindarajan, Srinath, Verheugen, Eveline, Coquet, Jonathan M., Staal, Jens, McGuire, Conor, Taghon, Tom, Leclercq, Georges, Beyaert, Rudi, van Loo, Geert, Lambrecht, Bart N., Elewaut, Dirk
Publicado 2016

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

por Van Caeneghem, Yasmine, De Munter, Stijn, Tieppo, Paola, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Debets, Reno, Vermijlen, David, Abken, Hinrich, Vandekerckhove, Bart
Publicado 2017