The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells

por Hennequart, Marc, Labuschagne, Christiaan F., Tajan, Mylène, Pilley, Steven E., Cheung, Eric C., Legrave, Nathalie M., Driscoll, Paul C., Vousden, Karen H.
Publicado 2021

The Tyrosine Phosphatase SHP2: A New Target for Insulin Resistance?

por Saint-Laurent, Céline, Mazeyrie, Laurène, Tajan, Mylène, Paccoud, Romain, Castan-Laurell, Isabelle, Valet, Philippe, Edouard, Thomas, Pradère, Jean-Philippe, Dray, Cédric, Yart, Armelle
Publicado 2022

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

por Tajan, Mylène, Hock, Andreas K., Blagih, Julianna, Robertson, Neil A., Labuschagne, Christiaan F., Kruiswijk, Flore, Humpton, Timothy J., Adams, Peter D., Vousden, Karen H.
Publicado 2018

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma

por D’Avola, Annalisa, Legrave, Nathalie, Tajan, Mylène, Chakravarty, Probir, Shearer, Ryan L., King, Hamish W., Kluckova, Katarina, Cheung, Eric C., Clear, Andrew J., Gunawan, Arief S., Zhang, Lingling, James, Louisa K., MacRae, James I., Gribben, John G., Calado, Dinis P., Vousden, Karen H., Riches, John C.
Publicado 2022

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

por Tajan, Mylène, Hennequart, Marc, Cheung, Eric C., Zani, Fabio, Hock, Andreas K., Legrave, Nathalie, Maddocks, Oliver D. K., Ridgway, Rachel A., Athineos, Dimitris, Suárez-Bonnet, Alejandro, Ludwig, Robert L., Novellasdemunt, Laura, Angelis, Nikolaos, Li, Vivian S. W., Vlachogiannis, Georgios, Valeri, Nicola, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Publicado 2021