C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner

por Leskelä, Stina, Huber, Nadine, Rostalski, Hannah, Natunen, Teemu, Remes, Anne M., Takalo, Mari, Hiltunen, Mikko, Haapasalo, Annakaisa
Publicado 2019

Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1

por Takalo, Mari, Viswanathan, Jayashree, Natunen, Teemu, Kurkinen, Kaisa MA, Tanila, Heikki, Soininen, Hilkka, Tanzi, Rudolph E, Hiltunen, Mikko, Haapasalo, Annakaisa
Publicado 2013

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer’s Disease

por Marttinen, Mikael, Takalo, Mari, Natunen, Teemu, Wittrahm, Rebekka, Gabbouj, Sami, Kemppainen, Susanna, Leinonen, Ville, Tanila, Heikki, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2018

Altered Insulin Signaling in Alzheimer’s Disease Brain – Special Emphasis on PI3K-Akt Pathway

por Gabbouj, Sami, Ryhänen, Simo, Marttinen, Mikael, Wittrahm, Rebekka, Takalo, Mari, Kemppainen, Susanna, Martiskainen, Henna, Tanila, Heikki, Haapasalo, Annakaisa, Hiltunen, Mikko, Natunen, Teemu
Publicado 2019

MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation

por Wittrahm, Rebekka, Takalo, Mari, Marttinen, Mikael, Kuulasmaa, Teemu, Mäkinen, Petra, Kemppainen, Susanna, Martiskainen, Henna, Rauramaa, Tuomas, Pike, Ian, Leinonen, Ville, Natunen, Teemu, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2021

Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers

por Martiskainen, Henna, Takalo, Mari, Solomon, Alina, Stančáková, Alena, Marttinen, Mikael, Natunen, Teemu, Haapasalo, Annakaisa, Herukka, Sanna‐Kaisa, Kuusisto, Johanna, Soininen, Hilkka, Kivipelto, Miia, Laakso, Markku, Hiltunen, Mikko
Publicado 2018

The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes immune functions

por Takalo, Mari, Wittrahm, Rebekka, Wefers, Benedikt, Parhizkar, Samira, Jokivarsi, Kimmo, Kuulasmaa, Teemu, Mäkinen, Petra, Martiskainen, Henna, Wurst, Wolfgang, Xiang, Xianyuan, Marttinen, Mikael, Poutiainen, Pekka, Haapasalo, Annakaisa, Hiltunen, Mikko, Haass, Christian
Publicado 2020

Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates

por Kemppainen, Susanna, Huber, Nadine, Willman, Roosa-Maria, Zamora, Ana, Mäkinen, Petra, Martiskainen, Henna, Takalo, Mari, Haapasalo, Annakaisa, Sobrino, Tomás, González Gómez, Manuel Antonio, Piñeiro, Yolanda, Rivas, José, Himmelreich, Uwe, Hiltunen, Mikko
Publicado 2023

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci

por Rostalski, Hannah, Hietanen, Tomi, Leskelä, Stina, Behánová, Andrea, Abdollahzadeh, Ali, Wittrahm, Rebekka, Mäkinen, Petra, Huber, Nadine, Hoffmann, Dorit, Solje, Eino, Remes, Anne M., Natunen, Teemu, Takalo, Mari, Tohka, Jussi, Hiltunen, Mikko, Haapasalo, Annakaisa
Publicado 2020

Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

por Marttinen, Mikael, Ferreira, Catarina B., Paldanius, Kaisa M. A., Takalo, Mari, Natunen, Teemu, Mäkinen, Petra, Leppänen, Luukas, Leinonen, Ville, Tanigaki, Kenji, Kang, Gina, Hiroi, Noboru, Soininen, Hilkka, Rilla, Kirsi, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2020

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death

por Martiskainen, Henna, Paldanius, Kaisa M. A., Natunen, Teemu, Takalo, Mari, Marttinen, Mikael, Leskelä, Stina, Huber, Nadine, Mäkinen, Petra, Bertling, Enni, Dhungana, Hiramani, Huuskonen, Mikko, Honkakoski, Paavo, Hotulainen, Pirta, Rilla, Kirsi, Koistinaho, Jari, Soininen, Hilkka, Malm, Tarja, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2017

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

por Natunen, Teemu, Martiskainen, Henna, Marttinen, Mikael, Gabbouj, Sami, Koivisto, Hennariikka, Kemppainen, Susanna, Kaipainen, Satu, Takalo, Mari, Svobodová, Helena, Leppänen, Luukas, Kemiläinen, Benjam, Ryhänen, Simo, Kuulasmaa, Teemu, Rahunen, Eija, Juutinen, Sisko, Mäkinen, Petra, Miettinen, Pasi, Rauramaa, Tuomas, Pihlajamäki, Jussi, Haapasalo, Annakaisa, Leinonen, Ville, Tanila, Heikki, Hiltunen, Mikko
Publicado 2020

Correction to: Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

por Eysert, Fanny, Coulon, Audrey, Boscher, Emmanuelle, Vreulx, Anaїs-Camille, Flaig, Amandine, Mendes, Tiago, Hughes, Sandrine, Grenier-Boley, Benjamin, Hanoulle, Xavier, Demiautte, Florie, Bauer, Charlotte, Marttinen, Mikael, Takalo, Mari, Amouyel, Philippe, Desai, Shruti, Pike, Ian, Hiltunen, Mikko, Chécler, Frédéric, Farinelli, Mélissa, Delay, Charlotte, Malmanche, Nicolas, Hébert, Sébastien S., Dumont, Julie, Kilinc, Devrim, Lambert, Jean-Charles, Chapuis, Julien
Publicado 2021

Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

por Eysert, Fanny, Coulon, Audrey, Boscher, Emmanuelle, Vreulx, Anaїs-Camille, Flaig, Amandine, Mendes, Tiago, Hughes, Sandrine, Grenier-Boley, Benjamin, Hanoulle, Xavier, Demiautte, Florie, Bauer, Charlotte, Marttinen, Mikael, Takalo, Mari, Amouyel, Philippe, Desai, Shruti, Pike, Ian, Hiltunen, Mikko, Chécler, Frédéric, Farinelli, Mélissa, Delay, Charlotte, Malmanche, Nicolas, Hébert, Sébastien S., Dumont, Julie, Kilinc, Devrim, Lambert, Jean-Charles, Chapuis, Julien
Publicado 2020