Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth

por Ochiya, Takahiro, Takenaga, Keizo, Endo, Hideya
Publicado 2013

Inhibition of the invasion and metastasis of mammary carcinoma cells by NBD peptide targeting S100A4 via the suppression of the Sp1/MMP-14 axis

por Takenaga, Keizo, Ochiya, Takahiro, Endo, Hideya
Publicado 2021

Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles

por Takenaga, Keizo, Koshikawa, Nobuko, Nagase, Hiroki
Publicado 2021

HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression

por Harashima, Nanae, Takenaga, Keizo, Akimoto, Miho, Harada, Mamoru
Publicado 2017

Involvement of Sl00–related Calcium–binding Protein pEL98 (or mts1) in Cell Motility and Tumor Cell Invasion

por Takenaga, Keizo, Nakamura, Yohko, Endo, Hideya, Sakiyama, Shigeru
Publicado 1994

Cloning of Mouse DAN cDNA and Its Down‐regulation in Transformed Cells

por Ozaki, Toshinori, Ma, Jun, Takenaga, Keizo, Sakiyama, Shigeru
Publicado 1996

Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model

por Takenaga, Keizo, Akimoto, Miho, Koshikawa, Nobuko, Nagase, Hiroki
Publicado 2020

Obesity reduces the anticancer effect of AdipoRon against orthotopic pancreatic cancer in diet-induced obese mice

por Takenaga, Keizo, Akimoto, Miho, Koshikawa, Nobuko, Nagase, Hiroki
Publicado 2021

Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death

por Akimoto, Miho, Iizuka, Mari, Kanematsu, Rie, Yoshida, Masato, Takenaga, Keizo
Publicado 2015

Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment

por Akimoto, Miho, Maruyama, Riruke, Takamaru, Hiroyuki, Ochiya, Takahiro, Takenaga, Keizo
Publicado 2016

Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis

por Akimoto, Miho, Maruyama, Riruke, Kawabata, Yasunari, Tajima, Yoshitsugu, Takenaga, Keizo
Publicado 2018

Association of predicted pathogenic mutations in mitochondrial ND genes with distant metastasis in NSCLC and colon cancer

por Koshikawa, Nobuko, Akimoto, Miho, Hayashi, Jun-Ichi, Nagase, Hiroki, Takenaga, Keizo
Publicado 2017

Mitochondria: Endosymbiont bacteria DNA sequence as a target against cancer

por Nagase, Hiroki, Watanabe, Takayoshi, Koshikawa, Nobuko, Yamamoto, Seigi, Takenaga, Keizo, Lin, Jason
Publicado 2021

MCT4 is induced by metastasis-enhancing pathogenic mitochondrial NADH dehydrogenase gene mutations and can be a therapeutic target

por Takenaga, Keizo, Koshikawa, Nobuko, Akimoto, Miho, Tatsumi, Yasutoshi, Lin, Jason, Itami, Makiko, Nagase, Hiroki
Publicado 2021

A PI polyamide–TPP conjugate targeting a mtDNA mutation induces cell death of cancer cells with the mutation

por Koshikawa, Nobuko, Yasui, Nanami, Kida, Yuki, Shinozaki, Yoshinao, Tsuji, Kohei, Watanabe, Takayoshi, Takenaga, Keizo, Nagase, Hiroki
Publicado 2021

Mitochondrial DNA Mutations Regulate Metastasis of Human Breast Cancer Cells

por Imanishi, Hirotake, Hattori, Keisuke, Wada, Reiko, Ishikawa, Kaori, Fukuda, Sayaka, Takenaga, Keizo, Nakada, Kazuto, Hayashi, Jun-Ichi
Publicado 2011

Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction

por Ochiya, Takahiro, Takenaga, Keizo, Asagiri, Masataka, Nakano, Kazumi, Satoh, Hitoshi, Watanabe, Toshiki, Imajoh-Ohmi, Shinobu, Endo, Hideya
Publicado 2015

Suppression of non‐small‐cell lung cancer A549 tumor growth by an mtDNA mutation‐targeting pyrrole‐imidazole polyamide‐triphenylphosphonium and a senolytic drug

por Tsuji, Kohei, Kida, Yuki, Koshikawa, Nobuko, Yamamoto, Seigi, Shinozaki, Yoshinao, Watanabe, Takayoshi, Lin, Jason, Nagase, Hiroki, Takenaga, Keizo
Publicado 2022

The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells

por Okamoto, Akihisa, Tanaka, Masahiro, Sumi, Chisato, Oku, Kanako, Kusunoki, Munenori, Nishi, Kenichiro, Matsuo, Yoshiyuki, Takenaga, Keizo, Shingu, Koh, Hirota, Kiichi
Publicado 2016

Hypoxia induces downregulation of the tumor-suppressive sST2 in colorectal cancer cells via the HIF–nuclear IL-33–GATA3 pathway

por Akimoto, Miho, Susa, Takao, Okudaira, Noriyuki, Koshikawa, Nobuko, Hisaki, Harumi, Iizuka, Masayoshi, Okinaga, Hiroko, Takenaga, Keizo, Okazaki, Tomoki, Tamamori-Adachi, Mimi
Publicado 2023