Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study

por Singh, Dave, Edwards, Lisa, Tal-Singer, Ruth, Rennard, Stephen
Publicado 2010

Fibrinogen, chronic obstructive pulmonary disease (COPD) and outcomes in two United States cohorts

por Valvi, Deepa, Mannino, David M, Müllerova, Hana, Tal-Singer, Ruth
Publicado 2012

Effect of inhaled corticosteroids on blood eosinophil count in steroid-naïve patients with COPD

por Kreindler, James L, Watkins, Michael L, Lettis, Sally, Tal-Singer, Ruth, Locantore, Nicholas
Publicado 2016

Altered Gene Expression in Blood and Sputum in COPD Frequent Exacerbators in the ECLIPSE Cohort

por Singh, Dave, Fox, Steven M., Tal-Singer, Ruth, Bates, Stewart, Riley, John H., Celli, Bartolome
Publicado 2014

Real-world use of rescue inhaler sensors, electronic symptom questionnaires and physical activity monitors in COPD

por Bowler, Russell, Allinder, Matthew, Jacobson, Sean, Miller, Andrew, Miller, Bruce, Tal-Singer, Ruth, Locantore, Nicholas
Publicado 2019

Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease

por Duvoix, Annelyse, Dickens, Jenny, Haq, Imran, Mannino, David, Miller, Bruce, Tal-Singer, Ruth, Lomas, David A
Publicado 2013

COPD association and repeatability of blood biomarkers in the ECLIPSE cohort

por Dickens, Jennifer A, Miller, Bruce E, Edwards, Lisa D, Silverman, Edwin K, Lomas, David A, Tal-Singer, Ruth
Publicado 2011

Multiple biomarkers predict disease severity, progression and mortality in COPD

por Zemans, Rachel L., Jacobson, Sean, Keene, Jason, Kechris, Katerina, Miller, Bruce E., Tal-Singer, Ruth, Bowler, Russell P.
Publicado 2017

Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study

por Sims, Michael W, Tal-Singer, Ruth M, Kierstein, Sonja, Musani, Ali I, Beers, Michael F, Panettieri, Reynold A, Haczku, Angela
Publicado 2008

Frailty: A global measure of the multisystem impact of COPD

por Gale, Nichola S, Albarrati, Ali M, Munnery, Margaret M, Hubbard, Ruth E, Tal-Singer, Ruth, Cockcroft, John R, Shale, Dennis J
Publicado 2018

CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial

por Lazaar, Aili L., Miller, Bruce E., Donald, Alison C., Keeley, Thomas, Ambery, Claire, Russell, John, Watz, Henrik, Tal-Singer, Ruth
Publicado 2020

The COPD Foundation's COPD360Net Initiative Approach to Patient-Centric Drug Development: A Case Study in Using Patient Surveys to Inform New Treatments for Viral Respiratory Infec...

por Tal-Singer, Ruth, Miller, Bruce E, Rommes, Jean M, Luttmann, Mark A, Demaison, Christophe, Bradley Drummond, M, Pasquale, Cara B
Publicado 2023

Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial

por Betts, Joanna C, Mayer, Ruth J, Tal-Singer, Ruth, Warnock, Linda, Clayton, Chris, Bates, Stewart, Hoffman, Bryan E, Larminie, Christopher, Singh, Dave
Publicado 2015

DSP variants may be associated with longitudinal change in quantitative emphysema

por Kim, Woori, Cho, Michael H., Sakornsakolpat, Phuwanat, Lynch, David A., Coxson, Harvey O., Tal-Singer, Ruth, Silverman, Edwin K., Beaty, Terri H.
Publicado 2019

Fluticasone Propionate Protects against Ozone-Induced Airway Inflammation and Modified Immune Cell Activation Markers in Healthy Volunteers

por Alexis, Neil E., Lay, John C., Haczku, Angela, Gong, Henry, Linn, William, Hazucha, Milan J., Harris, Brad, Tal-Singer, Ruth, Peden, David B.
Publicado 2008

The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756) − a selective CXCR2 antagonist − in healthy adult subjects

por Miller, Bruce E., Mistry, Sunil, Smart, Kevin, Connolly, Paul, Carpenter, Donald C., Cooray, Hiran, Bloomer, Jackie C., Tal-Singer, Ruth, Lazaar, Aili L.
Publicado 2015

Plasma microfibrillar-associated protein 4 is not prognostic of emphysema progression but is associated with cardiovascular disease history and mortality in COPD patients

por Johansson, Sofie Lock, Wulf-Johansson, Helle, Schlosser, Anders, Titlestad, Ingrid L., Miller, Bruce, Tal-Singer, Ruth, Holmskov, Uffe, Vestbo, Jørgen, Sørensen, Grith Lykke
Publicado 2019

Aortic Pulse Wave Velocity as a Measure of Cardiovascular Risk in Chronic Obstructive Pulmonary Disease: Two-Year Follow-Up Data from the ARCADE Study

por Gale, Nichola S., Albarrati, Ali M., Munnery, Margaret M., Mcdonnell, Barry J., Benson, Victoria S., Tal-Singer, Ruth M., Cockcroft, John R., Shale, Dennis J.
Publicado 2019

CXCL-8-dependent and -independent neutrophil activation in COPD: experiences from a pilot study of the CXCR2 antagonist danirixin

por Keir, Holly R., Richardson, Hollian, Fillmore, Christina, Shoemark, Amelia, Lazaar, Aili L., Miller, Bruce E., Tal-Singer, Ruth, Chalmers, James D., Mohan, Divya
Publicado 2020

High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD – results from the ECLIPSE study

por Sand, Jannie M. B., Leeming, Diana J., Byrjalsen, Inger, Bihlet, Asger R., Lange, Peter, Tal-Singer, Ruth, Miller, Bruce E., Karsdal, Morten A., Vestbo, Jørgen
Publicado 2016