The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch

por Talapatra, Sandeep K, Harker, Bethany, Welburn, Julie PI
Publicado 2015

The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping

por Chatrin, Chatrin, Talapatra, Sandeep K., Canard, Bruno, Kozielski, Frank
Publicado 2017

Modified Peptide Inhibitors of the Keap1–Nrf2 Protein–Protein Interaction Incorporating Unnatural Amino Acids

por Georgakopoulos, Nikolaos D., Talapatra, Sandeep K., Gatliff, Jemma, Kozielski, Frank, Wells, Geoff
Publicado 2018

Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases

por Riccio, Federica, Talapatra, Sandeep K., Oxenford, Sally, Angell, Richard, Mazzon, Michela, Kozielski, Frank
Publicado 2019

The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation

por McHugh, Toni, Zou, Juan, Volkov, Vladimir A., Bertin, Aurélie, Talapatra, Sandeep K., Rappsilber, Juri, Dogterom, Marileen, Welburn, Julie P. I.
Publicado 2019

Optimized S-Trityl-l-cysteine-Based Inhibitors of Kinesin Spindle Protein with Potent in Vivo Antitumor Activity in Lung Cancer Xenograft Models

por Good, James A. D., Wang, Fang, Rath, Oliver, Kaan, Hung Yi Kristal, Talapatra, Sandeep K., Podgórski, Dawid, MacKay, Simon P., Kozielski, Frank
Publicado 2013

Phenyl Bis-Sulfonamide Keap1-Nrf2 Protein–Protein Interaction Inhibitors with an Alternative Binding Mode

por Georgakopoulos, Nikolaos, Talapatra, Sandeep, Dikovskaya, Dina, Dayalan Naidu, Sharadha, Higgins, Maureen, Gatliff, Jemma, Ayhan, Aysel, Nikoloudaki, Roxani, Schaap, Marjolein, Valko, Klara, Javid, Farideh, Dinkova-Kostova, Albena T., Kozielski, Frank, Wells, Geoffrey
Publicado 2022