Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective

por Talevi, Alan
Publicado 2015

Antiseizure medication discovery: Recent and future paradigm shifts

por Talevi, Alan
Publicado 2022

Editorial: Lipid Nanoparticles as a Novel Strategy to Deliver Bioactive Molecules

por Talevi, Alan, Duran, Nelson, Castro, Guillermo Raul
Publicado 2021

In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2

por Alberca, Lucas N., Chuguransky, Sara R., Álvarez, Cora L., Talevi, Alan, Salas-Sarduy, Emir
Publicado 2019

Identification of Levothyroxine Antichagasic Activity through Computer-Aided Drug Repurposing

por Bellera, Carolina L., Balcazar, Darío E., Alberca, Lucas, Labriola, Carlos A., Talevi, Alan, Carrillo, Carolina
Publicado 2014

Development of Conformation Independent Computational Models for the Early Recognition of Breast Cancer Resistance Protein Substrates

por Gantner, Melisa Edith, Di Ianni, Mauricio Emiliano, Ruiz, María Esperanza, Talevi, Alan, Bruno-Blanch, Luis E.
Publicado 2013

Trypanosomatid-Caused Conditions: State of the Art of Therapeutics and Potential Applications of Lipid-Based Nanocarriers

por Muraca, Giuliana, Berti, Ignacio Rivero, Sbaraglini, María L., Fávaro, Wagner J., Durán, Nelson, Castro, Guillermo R., Talevi, Alan
Publicado 2020

Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions

por Auzmendi, Jerónimo, Palestro, Pablo, Blachman, Agustín, Gavernet, Luciana, Merelli, Amalia, Talevi, Alan, Calabrese, Graciela Cristina, Ramos, Alberto Javier, Lazarowski, Alberto
Publicado 2020

A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

por Llanos, Manuel A., Sbaraglini, María L., Villalba, María L., Ruiz, María D., Carrillo, Carolina, Alba Soto, Catalina, Talevi, Alan, Angeli, Andrea, Parkkila, Seppo, Supuran, Claudiu T., Gavernet, Luciana
Publicado 2019

Novel Phenobarbital-Loaded Nanostructured Lipid Carriers for Epilepsy Treatment: From QbD to In Vivo Evaluation

por Scioli-Montoto, Sebastian, Sbaraglini, Maria Laura, Cisneros, Jose Sebastian, Chain, Cecilia Yamil, Ferretti, Valeria, León, Ignacio Esteban, Alvarez, Vera Alejandra, Castro, Guillermo Raul, Islan, German Abel, Talevi, Alan, Ruiz, Maria Esperanza
Publicado 2022

Machine Learning in Drug Discovery and Development Part 1: A Primer

por Talevi, Alan, Morales, Juan Francisco, Hather, Gregory, Podichetty, Jagdeep T., Kim, Sarah, Bloomingdale, Peter C., Kim, Samuel, Burton, Jackson, Brown, Joshua D., Winterstein, Almut G., Schmidt, Stephan, White, Jensen Kael, Conrado, Daniela J.
Publicado 2020

Cascade Ligand- and Structure-Based Virtual Screening to Identify New Trypanocidal Compounds Inhibiting Putrescine Uptake

por Alberca, Lucas N., Sbaraglini, María L., Morales, Juan F., Dietrich, Roque, Ruiz, María D., Pino Martínez, Agustina M., Miranda, Cristian G., Fraccaroli, Laura, Alba Soto, Catalina D., Carrillo, Carolina, Palestro, Pablo H., Talevi, Alan
Publicado 2018

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

por Muraca, Giuliana, Ruiz, María Esperanza, Gambaro, Rocío C, Scioli-Montoto, Sebastián, Sbaraglini, María Laura, Padula, Gisel, Cisneros, José Sebastián, Chain, Cecilia Yamil, Álvarez, Vera A, Huck-Iriart, Cristián, Castro, Guillermo R, Piñero, María Belén, Marchetto, Matias Ildebrando, Alba Soto, Catalina, Islan, Germán A, Talevi, Alan
Publicado 2023

Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro

por Ruatta, Santiago M., Prada Gori, Denis N., Fló Díaz, Martín, Lorenzelli, Franca, Perelmuter, Karen, Alberca, Lucas N., Bellera, Carolina L., Medeiros, Andrea, López, Gloria V., Ingold, Mariana, Porcal, Williams, Dibello, Estefanía, Ihnatenko, Irina, Kunick, Conrad, Incerti, Marcelo, Luzardo, Martín, Colobbio, Maximiliano, Ramos, Juan Carlos, Manta, Eduardo, Minini, Lucía, Lavaggi, María Laura, Hernández, Paola, Šarlauskas, Jonas, Huerta García, César Sebastian, Castillo, Rafael, Hernández-Campos, Alicia, Ribaudo, Giovanni, Zagotto, Giuseppe, Carlucci, Renzo, Medrán, Noelia S., Labadie, Guillermo R., Martinez-Amezaga, Maitena, Delpiccolo, Carina M. L., Mata, Ernesto G., Scarone, Laura, Posada, Laura, Serra, Gloria, Calogeropoulou, Theodora, Prousis, Kyriakos, Detsi, Anastasia, Cabrera, Mauricio, Alvarez, Guzmán, Aicardo, Adrián, Araújo, Verena, Chavarría, Cecilia, Mašič, Lucija Peterlin, Gantner, Melisa E., Llanos, Manuel A., Rodríguez, Santiago, Gavernet, Luciana, Park, Soonju, Heo, Jinyeong, Lee, Honggun, Paul Park, Kyu-Ho, Bollati-Fogolín, Mariela, Pritsch, Otto, Shum, David, Talevi, Alan, Comini, Marcelo A.
Publicado 2023