Targeted Protein Degradation through E2 Recruitment

por Forte, Nafsika, Dovala, Dustin, Hesse, Matthew J., McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Publicado 2023

Accelerating antiviral drug discovery: lessons from COVID-19

por von Delft, Annette, Hall, Matthew D., Kwong, Ann D., Purcell, Lisa A., Saikatendu, Kumar Singh, Schmitz, Uli, Tallarico, John A., Lee, Alpha A.
Publicado 2023

Bardoxolone conjugation enables targeted protein degradation of BRD4

por Tong, Bingqi, Luo, Mai, Xie, Yi, Spradlin, Jessica N., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Publicado 2020

Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells

por Gowans, Flor A., Thach, Danny Q., Wang, Yangzhi, Altamirano Poblano, Belen E., Dovala, Dustin, Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Publicado 2023

Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design

por Page, Annika C. S., Scholz, Spencer O., Keenan, Katherine N., Spradlin, Jessica N., Belcher, Bridget P., Brittain, Scott M., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Nomura, Daniel K., Toste, F. Dean
Publicado 2022

Manumycin Polyketides Act as Molecular Glues Between UBR7 and P53

por Isobe, Yosuke, Okumura, Mikiko, McGregor, Lynn M., Brittain, Scott M., Jones, Michael D., Liang, Xiaoyou, White, Ross, Forrester, William, McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Publicado 2020

Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation

por Spradlin, Jessica N., Hu, Xirui, Ward, Carl C., Brittain, Scott M., Jones, Michael D., Ou, Lisha, To, Milton, Proudfoot, Andrew, Ornelas, Elizabeth, Woldegiorgis, Mikias, Olzmann, James A., Bussiere, Dirksen E., Thomas, Jason R., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Publicado 2019

Rational Chemical Design of Molecular Glue Degraders

por Toriki, Ethan S., Papatzimas, James W., Nishikawa, Kaila, Dovala, Dustin, Frank, Andreas O., Hesse, Matthew J., Dankova, Daniela, Song, Jae-Geun, Bruce-Smythe, Megan, Struble, Heidi, Garcia, Francisco J., Brittain, Scott M., Kile, Andrew C., McGregor, Lynn M., McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Publicado 2023

Correction to “Rational Chemical Design of Molecular Glue Degraders”

por Toriki, Ethan S., Papatzimas, James W., Nishikawa, Kaila, Dovala, Dustin, Frank, Andreas O., Hesse, Matthew J., Dankova, Daniela, Song, Jae-Geun, Bruce-Smythe, Megan, Struble, Heidi, Garcia, Francisco J., Brittain, Scott M., Kile, Andrew C., McGregor, Lynn M., McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Publicado 2023

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

por DeJesus, Rowena, Moretti, Francesca, McAllister, Gregory, Wang, Zuncai, Bergman, Phil, Liu, Shanming, Frias, Elizabeth, Alford, John, Reece-Hoyes, John S, Lindeman, Alicia, Kelliher, Jennifer, Russ, Carsten, Knehr, Judith, Carbone, Walter, Beibel, Martin, Roma, Guglielmo, Ng, Aylwin, Tallarico, John A, Porter, Jeffery A, Xavier, Ramnik J, Mickanin, Craig, Murphy, Leon O, Hoffman, Gregory R, Nyfeler, Beat
Publicado 2016

Selective and Specific Inhibition of the Plasmodium falciparum Lysyl-tRNA Synthetase by the Fungal Secondary Metabolite Cladosporin

por Hoepfner, Dominic, McNamara, Case W., Lim, Chek Shik, Studer, Christian, Riedl, Ralph, Aust, Thomas, McCormack, Susan L., Plouffe, David M., Meister, Stephan, Schuierer, Sven, Plikat, Uwe, Hartmann, Nicole, Staedtler, Frank, Cotesta, Simona, Schmitt, Esther K., Petersen, Frank, Supek, Frantisek, Glynne, Richard J., Tallarico, John A., Porter, Jeffrey A., Fishman, Mark C., Bodenreider, Christophe, Diagana, Thierry T., Movva, N. Rao, Winzeler, Elizabeth A.
Publicado 2012

Identification of Elongation Factor G as the Conserved Cellular Target of Argyrin B

por Nyfeler, Beat, Hoepfner, Dominic, Palestrant, Deborah, Kirby, Christina A., Whitehead, Lewis, Yu, Robert, Deng, Gejing, Caughlan, Ruth E., Woods, Angela L., Jones, Adriana K., Barnes, S. Whitney, Walker, John R., Gaulis, Swann, Hauy, Ervan, Brachmann, Saskia M., Krastel, Philipp, Studer, Christian, Riedl, Ralph, Estoppey, David, Aust, Thomas, Movva, N. Rao, Wang, Zuncai, Salcius, Michael, Michaud, Gregory A., McAllister, Gregory, Murphy, Leon O., Tallarico, John A., Wilson, Christopher J., Dean, Charles R.
Publicado 2012