Beta secretase activity in peripheral nerve regeneration

por Tallon, Carolyn, Farah, Mohamed H.
Publicado 2017

Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice

por Huang, Meixiang, Tallon, Carolyn, Zhu, Xiaolei, Huizar, Kaitlyn D. J., Picciolini, Silvia, Thomas, Ajit G., Tenora, Lukas, Liyanage, Wathsala, Rodà, Francesca, Gualerzi, Alice, Kannan, Rangaramanujam M., Bedoni, Marzia, Rais, Rana, Slusher, Barbara S.
Publicado 2023

Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis

por Hollinger, Kristen R., Sharma, Anjali, Tallon, Carolyn, Lovell, Lyndah, Thomas, Ajit G., Zhu, Xiaolei, Wiseman, Robyn, Wu, Ying, Kambhampati, Siva P., Liaw, Kevin, Sharma, Rishi, Rojas, Camilo, Rais, Rana, Kannan, Sujatha, Kannan, Rangaramanujam M., Slusher, Barbara S.
Publicado 2022

Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice

por Tallon, Carolyn, Bell, Benjamin J., Sharma, Anjali, Pal, Arindom, Malvankar, Medhinee M., Thomas, Ajit G., Yoo, Seung-Wan, Hollinger, Kristen R., Coleman, Kaleem, Wilkinson, Elizabeth L., Kannan, Sujatha, Haughey, Norman J., Kannan, Rangaramanujam M., Rais, Rana, Slusher, Barbara S.
Publicado 2022

Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer’s disease

por Tallon, Carolyn, Bell, Benjamin J, Malvankar, Medhinee M, Deme, Pragney, Nogueras-Ortiz, Carlos, Eren, Erden, Thomas, Ajit G, Hollinger, Kristen R, Pal, Arindom, Mustapic, Maja, Huang, Meixiang, Coleman, Kaleem, Joe, Tawnjerae R, Rais, Rana, Haughey, Norman J, Kapogiannis, Dimitrios, Slusher, Barbara S
Publicado 2023

Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model

por Tallon, Carolyn, Bell, Benjamin J., Malvankar, Medhinee M., Deme, Pragney, Nogueras-Ortiz, Carlos, Eren, Erden, Thomas, Ajit G., Hollinger, Kristen R., Pal, Arindom, Mustapic, Maja, Huang, Meixiang, Coleman, Kaleem, Joe, Tawnjerae R., Rais, Rana, Haughey, Norman J., Kapogiannis, Dimitrios, Slusher, Barbara S.
Publicado 2023

Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug

por Rais, Rana, Lemberg, Kathryn M., Tenora, Lukáš, Arwood, Matthew L., Pal, Arindom, Alt, Jesse, Wu, Ying, Lam, Jenny, Aguilar, Joanna Marie H., Zhao, Liang, Peters, Diane E., Tallon, Carolyn, Pandey, Rajeev, Thomas, Ajit G., Dash, Ranjeet P., Seiwert, Tanguy, Majer, Pavel, Leone, Robert D., Powell, Jonathan D., Slusher, Barbara S.
Publicado 2022