Unusual Base-Pairing Interactions in Monomer–Template Complexes

por Zhang, Wen, Tam, Chun Pong, Wang, Jiawei, Szostak, Jack W.
Publicado 2016

A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension

por Giurgiu, Constantin, Li, Li, O’Flaherty, Derek K., Tam, Chun Pong, Szostak, Jack W.
Publicado 2017

Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide

por Zhang, Wen, Tam, Chun Pong, Zhou, Lijun, Oh, Seung Soo, Wang, Jiawei, Szostak, Jack W.
Publicado 2018

Synthesis of a Nonhydrolyzable Nucleotide Phosphoroimidazolide Analogue That Catalyzes Nonenzymatic RNA Primer Extension

por Tam, Chun Pong, Zhou, Lijun, Fahrenbach, Albert C., Zhang, Wen, Walton, Travis, Szostak, Jack W.
Publicado 2017

Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer–Template Complexes

por Tam, Chun Pong, Fahrenbach, Albert C., Björkbom, Anders, Prywes, Noam, Izgu, Enver Cagri, Szostak, Jack W.
Publicado 2017

Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation

por Fahrenbach, Albert C., Giurgiu, Constantin, Tam, Chun Pong, Li, Li, Hongo, Yayoi, Aono, Masashi, Szostak, Jack W.
Publicado 2017

Bidirectional Direct Sequencing of Noncanonical RNA by Two-Dimensional Analysis of Mass Chromatograms

por Björkbom, Anders, Lelyveld, Victor S., Zhang, Shenglong, Zhang, Weicheng, Tam, Chun Pong, Blain, J. Craig, Szostak, Jack W.
Publicado 2015

Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization

por Zhang, Wen, Kim, Seohyun Chris, Tam, Chun Pong, Lelyveld, Victor S, Bala, Saikat, Chaput, John C, Szostak, Jack W
Publicado 2020

Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides

por Li, Li, Prywes, Noam, Tam, Chun Pong, O’Flaherty, Derek K., Lelyveld, Victor S., Izgu, Enver Cagri, Pal, Ayan, Szostak, Jack W.
Publicado 2017