Shifting the Gears of Metabolic Plasticity to Drive Cell State Transitions in Cancer

por Wu, Zhengwei, Lee, Yi Fei, Yeo, Xun Hui, Loo, Ser Yue, Tam, Wai Leong
Publicado 2021

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

por Ye, Xin, Tam, Wai Leong, Shibue, Tsukasa, Kaygusuz, Yasemin, Reinhardt, Ferenc, Eaton, Elinor, Weinberg, Robert A.
Publicado 2015

UniPath: a uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles

por Chawla, Smriti, Samydurai, Sudhagar, Kong, Say Li, Wu, Zhengwei, Wang, Zhenxun, TAM, Wai Leong, Sengupta, Debarka, Kumar, Vibhor
Publicado 2020

UniPath: a uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles

por Chawla, Smriti, Samydurai, Sudhagar, Kong, Say Li, Wu, Zhengwei, Wang, Zhenxun, TAM, Wai Leong, Sengupta, Debarka, Kumar, Vibhor
Publicado 2021

Mfap4: a promising target for enhanced liver regeneration and chronic liver disease treatment

por Iakovleva, Viktoriia, Wuestefeld, Anna, Ong, Agnes Bee Leng, Gao, Rong, Kaya, Neslihan Arife, Lee, May Yin, Zhai, Weiwei, Tam, Wai Leong, Dan, Yock Young, Wuestefeld, Torsten
Publicado 2023

Novel carfilzomib-based combinations as potential therapeutic strategies for liposarcomas

por Jeitany, Maya, Prabhu, Aishvaryaa, Dakle, Pushkar, Pathak, Elina, Madan, Vikas, Kanojia, Deepika, Mukundan, Vineeth, Jiang, Yan Yi, Landesman, Yosef, Tam, Wai Leong, Kappei, Dennis, Koeffler, H. Phillip
Publicado 2020

miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation

por Adusumilli, Lavanya, Facchinello, Nicola, Teh, Cathleen, Busolin, Giorgia, Le, Minh TN, Yang, Henry, Beffagna, Giorgia, Campanaro, Stefano, Tam, Wai Leong, Argenton, Francesco, Lim, Bing, Korzh, Vladimir, Tiso, Natascia
Publicado 2020

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

por Katz, Yarden, Li, Feifei, Lambert, Nicole J, Sokol, Ethan S, Tam, Wai-Leong, Cheng, Albert W, Airoldi, Edoardo M, Lengner, Christopher J, Gupta, Piyush B, Yu, Zhengquan, Jaenisch, Rudolf, Burge, Christopher B
Publicado 2014

Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer

por Lee, Yong-An, Lek, Chee Chong Jonathan, Rong, Gao, Wu, Zhengwei, Shathishwaran, S, Lee, Jia Hui Jane, Tam, Wai Leong, Wuestefeld, Torsten, Park, Sung-Jin, Jung, Sangyong, Kim, Beomsue, Kang, Nam-Young, Chang, Young-Tae
Publicado 2023

Tbx3 improves the germ-line competency of induced pluripotent stem cells

por Han, Jianyong, Yuan, Ping, Yang, Henry, Zhang, Jinqiu, Soh, Boon Seng, Li, Pin, Lim, Siew Lan, Cao, Suying, Tay, Junliang, Orlov, Yuriy L., Lufkin, Thomas, Ng, Huck-Hui, Tam, Wai-Leong, Lim, Bing
Publicado 2010

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)

por Kusuma, Frances Karla, Prabhu, Aishvaryaa, Tieo, Galen, Ahmed, Syed Moiz, Dakle, Pushkar, Yong, Wai Khang, Pathak, Elina, Madan, Vikas, Jiang, Yan Yi, Tam, Wai Leong, Kappei, Dennis, Dröge, Peter, Koeffler, H. Phillip, Jeitany, Maya
Publicado 2023

Robust delivery of RIG‐I agonists using extracellular vesicles for anti‐cancer immunotherapy

por Peng, Boya, Nguyen, Trinh Mai, Jayasinghe, Migara Kavishka, Gao, Chang, Pham, Thach Tuan, Vu, Luyen Tien, Yeo, Eric Yew Meng, Yap, Gracemary, Wang, Lingzhi, Goh, Boon Cher, Tam, Wai Leong, Luo, Dahai, Le, Minh TN
Publicado 2022

Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity

por Wang, Yu-Hsiu, Ho, Teresa L. F., Hariharan, Anushya, Goh, Hui Chin, Wong, Yao Liang, Verkaik, Nicole S., Lee, May Yin, Tam, Wai Leong, van Gent, Dik C., Venkitaraman, Ashok R., Sheetz, Michael P., Lane, David P.
Publicado 2022

The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer

por Yeo, Xun Hui, Sundararajan, Vignesh, Wu, Zhengwei, Phua, Zi Jin Cheryl, Ho, Yin Ying, Peh, Kai Lay Esther, Chiu, Yi-Chia, Tan, Tuan Zea, Kappei, Dennis, Ho, Ying Swan, Tan, David Shao Peng, Tam, Wai Leong, Huang, Ruby Yun-Ju
Publicado 2023

Author Correction: The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer

por Yeo, Xun Hui, Sundararajan, Vignesh, Wu, Zhengwei, Phua, Zi Jin Cheryl, Ho, Yin Ying, Peh, Kai Lay Esther, Chiu, Yi-Chia, Tan, Tuan Zea, Kappei, Dennis, Ho, Ying Swan, Tan, David Shao Peng, Tam, Wai Leong, Huang, Ruby Yun-Ju
Publicado 2023

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel

por Wee, Zhen Ning, Yatim, Siti Maryam J. M., Kohlbauer, Vera K, Feng, Min, Goh, Jian Yuan, Yi, Bao, Lee, Puay Leng, Zhang, Songjing, Wang, Pan Pan, Lim, Elgene, Tam, Wai Leong, Cai, Yu, Ditzel, Henrik J, Hoon, Dave S. B., Tan, Ern Yu, Yu, Qiang
Publicado 2015

Correction: Corrigendum: IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel

por Wee, Zhen Ning, Yatim, Siti Maryam J. M., Kohlabauer, Vera K., Feng, Min, Goh, Jian Yuan, Bao, Yi, Lee, Puay Leng, Zhang, Songjing, Wang, Pan Pan, Lim, Elgene, Tam, Wai Leong, Cai, Yu, Ditzel, Henrik J., Hoon, Dave S. B., Tan, Ern Yu, Yu, Qiang
Publicado 2015

B-MYB Is Essential for Normal Cell Cycle Progression and Chromosomal Stability of Embryonic Stem Cells

por Tarasov, Kirill V., Tarasova, Yelena S., Tam, Wai Leong, Riordon, Daniel R., Elliott, Steven T., Kania, Gabriela, Li, Jinliang, Yamanaka, Satoshi, Crider, David G., Testa, Gianluca, Li, Ronald A., Lim, Bing, Stewart, Colin L., Liu, Yie, Van Eyk, Jennifer E., Wersto, Robert P., Wobus, Anna M., Boheler, Kenneth R.
Publicado 2008

Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies

por Saei, Azad, Palafox, Marta, Benoukraf, Touati, Kumari, Nishi, Jaynes, Patrick William, Iyengar, Prasanna Vasudevan, Muñoz-Couselo, Eva, Nuciforo, Paolo, Cortés, Javier, Nötzel, Christopher, Kumarakulasinghe, Nesaretnam Barr, Richard, John Lalith Charles, Bin Adam Isa, Zul Fazreen, Pang, Brendan, Guzman, Marta, Siqin, Zhou, Yang, Henry, Tam, Wai Leong, Serra, Violeta, Eichhorn, Pieter Johan Adam
Publicado 2018

Integrative multi-omics landscape of fluoxetine action across 27 brain regions reveals global increase in energy metabolism and region-specific chromatin remodelling

por Rayan, Nirmala Arul, Kumar, Vibhor, Aow, Jonathan, Rastegar, Naghmeh, Lim, Michelle Gek Liang, O’Toole, Nicholas, Aliwarga, Edita, Arcego, Danusa Mar, Yeo, Hui Ting Grace, Wong, Jen Yi, Lee, May Yin, Schmidt, Florian, Haja, Hajira Shreen, Tam, Wai Leong, Zhang, Tie-Yuan, Diorio, Josie, Anacker, Christoph, Hen, Rene, Parent, Carine, Meaney, Michael J, Prabhakar, Shyam
Publicado 2022