Evaluation of a self-amplifying mRNA reporter vaccine in explant models of broiler chickens

por Snoeck, Janne, Chiers, Koen, Tam, Ying, Sanders, Niek N., Garmyn, An
Publicado 2023

Lipid Nanoparticle Delivery Systems to Enable mRNA-Based Therapeutics

por Semple, Sean C., Leone, Robert, Barbosa, Christopher J., Tam, Ying K., Lin, Paulo J. C.
Publicado 2022

mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model

por Sittplangkoon, Chutamath, Alameh, Mohamad-Gabriel, Weissman, Drew, Lin, Paulo J. C., Tam, Ying K., Prompetchara, Eakachai, Palaga, Tanapat
Publicado 2022

Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA

por Rizvi, Fatima, Everton, Elissa, Smith, Anna R., Liu, Hua, Osota, Elizabeth, Beattie, Mitchell, Tam, Ying, Pardi, Norbert, Weissman, Drew, Gouon-Evans, Valerie
Publicado 2021

Author Correction: Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA

por Rizvi, Fatima, Everton, Elissa, Smith, Anna R., Liu, Hua, Osota, Elizabeth, Beattie, Mitchell, Tam, Ying, Pardi, Norbert, Weissman, Drew, Gouon-Evans, Valerie
Publicado 2021

Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity

por Liu, Wei, Alameh, Mohamad-Gabriel, Yang, June F., Xu, Jonathan R., Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, You, Jianxin
Publicado 2022

Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin

por Huysmans, Hanne, Zhong, Zifu, De Temmerman, Joyca, Mui, Barbara L., Tam, Ying K., Mc Cafferty, Séan, Gitsels, Arlieke, Vanrompay, Daisy, Sanders, Niek N.
Publicado 2019

Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines

por Lutz, Johannes, Lazzaro, Sandra, Habbeddine, Mohamed, Schmidt, Kim Ellen, Baumhof, Patrick, Mui, Barbara L., Tam, Ying K., Madden, Thomas D., Hope, Michael J., Heidenreich, Regina, Fotin-Mleczek, Mariola
Publicado 2017

Antigen modifications improve nucleoside-modified mRNA-based influenza virus vaccines in mice

por Freyn, Alec W., Pine, Matthew, Rosado, Victoria C., Benz, Marcel, Muramatsu, Hiromi, Beattie, Mitchell, Tam, Ying K., Krammer, Florian, Palese, Peter, Nachbagauer, Raffael, McMahon, Meagan, Pardi, Norbert
Publicado 2021

Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS

por Waghela, Ishita N., Mallory, Katherine L., Taylor, Justin A., Schneider, Cosette G., Savransky, Tatyana, Janse, Chris J., Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, Angov, Evelina
Publicado 2022

Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals

por Connors, Jennifer, Joyner, David, Mege, Nathan, Cusimano, Gina, Bell, Matthew, Marcy, Jennifer, Taramangalam, Bhavani, Lin, Paulo, Tam, Ying, Lin, Paulo, Weissman, Drew, Kutzler, Michele, Alameh, Mohamad-Gabriel, Haddad, Elias
Publicado 2022

Nucleoside-Modified mRNA Vaccines Protect IFNAR(–/–) Mice against Crimean-Congo Hemorrhagic Fever Virus Infection

por Appelberg, Sofia, John, Lijo, Pardi, Norbert, Végvári, Ákos, Bereczky, Sándor, Ahlén, Gustaf, Monteil, Vanessa, Abdurahman, Samir, Mikaeloff, Flora, Beattie, Mitchell, Tam, Ying, Sällberg, Matti, Neogi, Ujjwal, Weissman, Drew, Mirazimi, Ali
Publicado 2022

Author Correction: mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

por Hayashi, Clifford T. H., Cao, Yi, Clark, Leor C., Tripathi, Abhai K., Zavala, Fidel, Dwivedi, Garima, Knox, James, Alameh, Mohamad-Gabriel, Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, Kumar, Nirbhay
Publicado 2023

mRNA mediates passive vaccination against infectious agents, toxins, and tumors

por Thran, Moritz, Mukherjee, Jean, Pönisch, Marion, Fiedler, Katja, Thess, Andreas, Mui, Barbara L, Hope, Michael J, Tam, Ying K, Horscroft, Nigel, Heidenreich, Regina, Fotin‐Mleczek, Mariola, Shoemaker, Charles B, Schlake, Thomas
Publicado 2017

mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

por Hayashi, Clifford T. H., Cao, Yi, Clark, Leor C., Tripathi, Abhai K., Zavala, Fidel, Dwivedi, Garima, Knox, James, Alameh, Mohamad-Gabriel, Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, Kumar, Nirbhay
Publicado 2022

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

por Belliveau, Nathan M, Huft, Jens, Lin, Paulo JC, Chen, Sam, Leung, Alex KK, Leaver, Timothy J, Wild, Andre W, Lee, Justin B, Taylor, Robert J, Tam, Ying K, Hansen, Carl L, Cullis, Pieter R
Publicado 2012

Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs

por Tombácz, István, Laczkó, Dorottya, Shahnawaz, Hamna, Muramatsu, Hiromi, Natesan, Ambika, Yadegari, Amir, Papp, Tyler E., Alameh, Mohamad-Gabriel, Shuvaev, Vladimir, Mui, Barbara L., Tam, Ying K., Muzykantov, Vladimir, Pardi, Norbert, Weissman, Drew, Parhiz, Hamideh
Publicado 2021

Development of a pentavalent broadly protective nucleoside-modified mRNA vaccine against influenza B viruses

por Pardi, Norbert, Carreño, Juan Manuel, O’Dell, George, Tan, Jessica, Bajusz, Csaba, Muramatsu, Hiromi, Rijnink, Willemijn, Strohmeier, Shirin, Loganathan, Madhumathi, Bielak, Dominika, Sung, Molly M. H., Tam, Ying K., Krammer, Florian, McMahon, Meagan
Publicado 2022

A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo

por Lee, Justin B, Zhang, Kaixin, Tam, Yuen Yi C, Quick, Joslyn, Tam, Ying K, Lin, Paulo JC, Chen, Sam, Liu, Yan, Nair, Jayaprakash K, Zlatev, Ivan, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Rennie, Paul S, Cullis, Pieter R
Publicado 2016

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies

por Pardi, Norbert, Parkhouse, Kaela, Kirkpatrick, Ericka, McMahon, Meagan, Zost, Seth J., Mui, Barbara L., Tam, Ying K., Karikó, Katalin, Barbosa, Christopher J., Madden, Thomas D., Hope, Michael J., Krammer, Florian, Hensley, Scott E., Weissman, Drew
Publicado 2018