HER2 and HER3 cooperatively regulate cancer cell growth and determine sensitivity to the novel investigational EGFR/HER2 kinase inhibitor TAK-285

por Takagi, Shinji, Banno, Hiroshi, Hayashi, Akira, Tamura, Toshiya, Ishikawa, Tomoyasu, Ohta, Yoshikazu
Publicado 2014

Antitumor Activity of TAK-285, an Investigational, Non-Pgp Substrate HER2/EGFR Kinase Inhibitor, in Cultured Tumor Cells, Mouse and Rat Xenograft Tumors, and in an HER2-Positive Br...

por Nakayama, Akiko, Takagi, Shinji, Yusa, Tadashi, Yaguchi, Masahiro, Hayashi, Akira, Tamura, Toshiya, Kawakita, Youichi, Ishikawa, Tomoyasu, Ohta, Yoshikazu
Publicado 2013

Panitumumab interaction with TAS‐102 leads to combinational anticancer effects via blocking of EGFR‐mediated tumor response to trifluridine

por Baba, Yuji, Tamura, Toshiya, Satoh, Yoshihiko, Gotou, Masamitsu, Sawada, Hiroshi, Ebara, Shunsuke, Shibuya, Kazunori, Soeda, Jumpei, Nakamura, Kazuhide
Publicado 2017

Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors

por Okegawa, Takatsugu, Morimoto, Megumi, Nishizawa, Satoru, Kitazawa, Satoshi, Honda, Kohei, Araki, Hideo, Tamura, Toshiya, Ando, Ayumi, Satomi, Yoshinori, Nutahara, Kikuo, Hara, Takahito
Publicado 2017

Two Secreted Proteoglycans, Activators of Urothelial Cell–Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression

por Papadaki, Vasiliki, Asada, Ken, Watson, Julie K., Tamura, Toshiya, Leung, Alex, Hopkins, Jack, Dellett, Margaret, Sasai, Noriaki, Davaapil, Hongorzul, Nik-Zainal, Serena, Longbottom, Rebecca, Nakakido, Makoto, Torii, Ryo, Veerakumarasivam, Abhi, Kaneko, Syuzo, Sagoo, Mandeep S., Murphy, Gillian, Mitani, Akihisa, Tsumoto, Kohei, Kelly, John D., Hamamoto, Ryuji, Ohnuma, Shin-ichi
Publicado 2020

Anti‐tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC‐dependent vulnerability

por Iwai, Kenichi, Yaguchi, Masahiro, Nishimura, Kazuho, Yamamoto, Yukiko, Tamura, Toshiya, Nakata, Daisuke, Dairiki, Ryo, Kawakita, Yoichi, Mizojiri, Ryo, Ito, Yoshiteru, Asano, Moriteru, Maezaki, Hironobu, Nakayama, Yusuke, Kaishima, Misato, Hayashi, Kozo, Teratani, Mika, Miyakawa, Shuichi, Iwatani, Misa, Miyamoto, Maki, Klein, Michael G, Lane, Wes, Snell, Gyorgy, Tjhen, Richard, He, Xingyue, Pulukuri, Sai, Nomura, Toshiyuki
Publicado 2018