Family-level stereoselective synthesis and biological evaluation of pyrrolomorpholine spiroketal natural product antioxidants

por Verano, Alyssa L., Tan, Derek S.
Publicado 2017

Solvent-Dependent Divergent Functions of Sc(OTf)(3) in Stereoselective Epoxide-Opening Spiroketalizations

por Sharma, Indrajeet, Wurst, Jacqueline M., Tan, Derek S.
Publicado 2014

Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion

por Bauer, Renato A., Wenderski, Todd A., Tan, Derek S.
Publicado 2012

General Platform for Systematic Quantitative Evaluation of Small-Molecule Permeability in Bacteria

por Davis, Tony D., Gerry, Christopher J., Tan, Derek S.
Publicado 2014

Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis

por Fernández-Tejada, Alberto, Tan, Derek S., Gin, David Y.
Publicado 2016

Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors

por Lux, Michaelyn C., Standke, Lisa C., Tan, Derek S.
Publicado 2019

Diastereoselective Synthesis of Highly Substituted Tetrahydrofurans by Pd-Catalyzed Tandem Oxidative Cyclization–Redox Relay Reactions Controlled by Intramolecular Hydrogen Bonding...

por Brooks, Joshua L., Xu, Liping, Wiest, Olaf, Tan, Derek S.
Publicado 2016

Diversity-Oriented Synthesis Approach to Macrocycles via Oxidative Ring Expansion

por Kopp, Felix, Stratton, Christopher F., Akella, Lakshmi B., Tan, Derek S.
Publicado 2012

Stereoselective Synthesis, Docking, and Biological Evaluation of Difluoroindanediol-Based MenE Inhibitors as Antibiotics

por Evans, Christopher E., Matarlo, Joe S., Tonge, Peter J., Tan, Derek S.
Publicado 2016

Active site remodeling accompanies thioester bond formation in the SUMO E1

por Olsen, Shaun K., Capili, Allan D., Lu, Xuequan, Tan, Derek S., Lima, Christopher D.
Publicado 2010

Diisonitrile Lipopeptides Mediate Resistance to Copper Starvation in Pathogenic Mycobacteria

por Buglino, John A., Ozakman, Yaprak, Xu, Yao, Chowdhury, Farhan, Tan, Derek S., Glickman, Michael S.
Publicado 2022

Direct conversion of amino acids to oxetanol bioisosteres via photoredox catalysis

por Delos Reyes, Avelyn Mae V., Nieves Escobar, Christopher S., Muñoz, Alberto, Huffman, Maya I., Tan, Derek S.
Publicado 2023

Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE

por Evans, Christopher E., Si, Yuanyuan, Matarlo, Joe S., Yin, Yue, French, Jarrod B., Tonge, Peter J., Tan, Derek S.
Publicado 2019

Structural basis for adenylation and thioester bond formation in the ubiquitin E1

por Hann, Zachary S., Ji, Cheng, Olsen, Shaun K., Lu, Xuequan, Lux, Michaelyn C., Tan, Derek S., Lima, Christopher D.
Publicado 2019

Quillaja saponin variants with central glycosidic linkage modifications exhibit distinct conformations and adjuvant activities

por Walkowicz, William E., Fernández-Tejada, Alberto, George, Constantine, Corzana, Francisco, Jiménez-Barbero, Jesús, Ragupathi, Govind, Tan, Derek S., Gin, David Y.
Publicado 2016

Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa

por Ji, Cheng, Sharma, Indrajeet, Pratihar, Debarshi, Hudson, L. Lynn, Maura, Damien, Guney, Tezcan, Rahme, Laurence G., Pesci, Everett C., Coleman, James P., Tan, Derek S.
Publicado 2016

Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa

por Ji, Cheng, Sharma, Indrajeet, Pratihar, Debarshi, Hudson, L. Lynn, Maura, Damien, Guney, Tezcan, Rahme, Laurence G., Pesci, Everett C., Coleman, James P., Tan, Derek S.
Publicado 2019

Development of a minimal saponin vaccine adjuvant based on QS-21

por Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Pillarsetty, NagaVaraKishore, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Lewis, Jason S., Tan, Derek S., Gin, David Y.
Publicado 2014

Host-cell Interactions of Engineered T cell Micropharmacies

por Bourne, Christopher M., Wallisch, Patrick, Dacek, Megan, Gardner, Thomas, Pierre, Stephanie, Vogt, Kristen, Corless, Broderick C., Bah, Mamadou A., Romero Pichardo, Jesus, Charles, Angel, Kurtz, Keifer G., Tan, Derek S., Scheinberg, David A.
Publicado 2023

Host Interactions with Engineered T-cell Micropharmacies

por Bourne, Christopher M., Wallisch, Patrick, Dacek, Megan M., Gardner, Thomas J., Pierre, Stephanie, Vogt, Kristen, Corless, Broderick C., Bah, Mamadou A., Romero-Pichardo, Jesus E., Charles, Angel, Kurtz, Keifer G., Tan, Derek S., Scheinberg, David A.
Publicado 2023