“Rogue” neutrophil-subset [DEspR+CD11b+/CD66b+] immunotype is an actionable therapeutic target for neutrophilic inflammation-mediated tissue injury – studies in human, macaque and...

por Carstensen, Saskia, Müller, Meike, Tan, Glaiza L. A., Pasion, Khristine Amber, Hohlfeld, Jens M., Herrera, Victoria L. M., Ruiz-Opazo, Nelson
Publicado 2022

Humanized anti-DEspR IgG4(S228P) antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis rat(nu/nu) model

por Gromisch, Christopher M., Tan, Glaiza L. A., Pasion, Khristine Amber, Moran, Ann-Marie, Gromisch, Matthew S., Grinstaff, Mark W., Carr, Francis J., Herrera, Victoria L. M., Ruiz-Opazo, Nelson
Publicado 2021

Anti-DEspR antibody treatment improves survival and reduces neurologic deficits in a hypertensive, spontaneous intracerebral hemorrhage (hsICH) rat model

por Herrera, Victoria L. M., Gromisch, Christopher M., Decano, Julius L., Pasion, Khristine Amber, Tan, Glaiza L. A., Hua, Ning, Takahashi, Courtney E., Greer, David M., Ruiz-Opazo, Nelson
Publicado 2023