Attenuated dengue viruses are genetically more diverse than their respective wild-type parents

por Bifani, Amanda Makha, Choy, Milly M., Tan, Hwee Cheng, Ooi, Eng Eong
Publicado 2021

Cell Strain-Derived Induced Pluripotent Stem Cells as an Isogenic Approach To Investigate Age-Related Host Response to Flaviviral Infection

por Bifani, Amanda M., Tan, Hwee Cheng, Choy, Milly M., Ooi, Eng Eong
Publicado 2022

Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent Infection

por Choy, Milly M., Zhang, Summer L., Costa, Vivian V., Tan, Hwee Cheng, Horrevorts, Sophie, Ooi, Eng Eong
Publicado 2015

Dengue virus compartmentalization during antibody-enhanced infection

por Ong, Eugenia Z., Zhang, Summer L., Tan, Hwee Cheng, Gan, Esther S., Chan, Kuan Rong, Ooi, Eng Eong
Publicado 2017

A protocol to assess cellular bioenergetics in flavivirus-infected cells

por Low, John Z.H., Yau, Clement, Zhang, Summer L.X., Tan, Hwee Cheng, Ooi, Eng Eong, Chan, Kuan Rong
Publicado 2022

Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes

por Poggianella, Monica, Slon Campos, José L., Chan, Kuan Rong, Tan, Hwee Cheng, Bestagno, Marco, Ooi, Eng Eong, Burrone, Oscar R.
Publicado 2015

Inhibition of SARS Coronavirus Infection In Vitro with Clinically Approved Antiviral Drugs

por Tan, Emily L.C., Ooi, Eng Eong, Lin, Chin-Yo, Tan, Hwee Cheng, Ling, Ai Ee, Lim, Bing, Stanton, Lawrence W.
Publicado 2004

Dengue Virus Neutralization in Cells Expressing Fc Gamma Receptors

por Chawla, Tanu, Chan, Kuan Rong, Zhang, Summer L., Tan, Hwee Cheng, Lim, Angeline P. C., Hanson, Brendon J., Ooi, Eng Eong
Publicado 2013

Positive epistasis between viral polymerase and the 3′ untranslated region of its genome reveals the epidemiologic fitness of dengue virus

por Syenina, Ayesa, Vijaykrishna, Dhanasekaran, Gan, Esther Shuyi, Tan, Hwee Cheng, Choy, Milly M., Siriphanitchakorn, Tanamas, Cheng, Colin, Vasudevan, Subhash G., Ooi, Eng Eong
Publicado 2020

Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes

por Gan, Esther Shuyi, Tan, Hwee Cheng, Le, Duyen Huynh Thi, Huynh, Trieu Trung, Wills, Bridget, Seidah, Nabil G., Ooi, Eng Eong, Yacoub, Sophie
Publicado 2020

A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection

por Gan, Esther S., Syenina, Ayesa, Linster, Martin, Ng, Benson, Zhang, Summer L., Watanabe, Satoru, Rajarethinam, Ravisankar, Tan, Hwee Cheng, Smith, Gavin JD., Ooi, Eng Eong
Publicado 2021

Hypoxia enhances antibody‐dependent dengue virus infection

por Gan, Esther Shuyi, Cheong, Wei Fun, Chan, Kuan Rong, Ong, Eugenia Ziying, Chai, Xiaoran, Tan, Hwee Cheng, Ghosh, Sujoy, Wenk, Markus R, Ooi, Eng Eong
Publicado 2017

Dengue virus activates cGAS through the release of mitochondrial DNA

por Sun, Bo, Sundström, Karin B., Chew, Jun Jie, Bist, Pradeep, Gan, Esther S., Tan, Hwee Cheng, Goh, Kenneth C., Chawla, Tanu, Tang, Choon Kit, Ooi, Eng Eong
Publicado 2017

Cross-Reactivity and Anti-viral Function of Dengue Capsid and NS3-Specific Memory T Cells Toward Zika Virus

por Lim, Mei Qiu, Kumaran, Emmanuelle A. P., Tan, Hwee Cheng, Lye, David C., Leo, Yee Sin, Ooi, Eng Eong, MacAry, Paul A., Bertoletti, Antonio, Rivino, Laura
Publicado 2018

A fast-growing dengue virus mutant reveals a dual role of STING in response to infection

por Ng, Wy Ching, Kwek, Swee Sen, Sun, Bo, Yousefi, Meisam, Ong, Eugenia Z., Tan, Hwee Cheng, Puschnik, Andreas S., Chan, Kuan Rong, Ooi, Yaw Shin, Ooi, Eng Eong
Publicado 2022

Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution

por Ong, Eugenia Z, Kalimuddin, Shirin, Chia, Wen Chong, Ooi, Sarah H, Koh, Clara WT, Tan, Hwee Cheng, Zhang, Summer L, Low, Jenny G, Ooi, Eng Eong, Chan, Kuan Rong
Publicado 2021

Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection

por Yau, Clement, Gan, Esther Shuyi, Kwek, Swee Sen, Tan, Hwee Cheng, Ong, Eugenia Z., Hamis, Noor Zayanah, Rivino, Laura, Chan, Kuan Rong, Watanabe, Satoru, Vasudevan, Subhash G., Ooi, Eng Eong
Publicado 2020

First Experimental In Vivo Model of Enhanced Dengue Disease Severity through Maternally Acquired Heterotypic Dengue Antibodies

por Ng, Jowin Kai Wei, Zhang, Summer Lixin, Tan, Hwee Cheng, Yan, Benedict, Maria Martinez Gomez, Julia, Tan, Wei Yu, Lam, Jian Hang, Tan, Grace Kai Xin, Ooi, Eng Eong, Alonso, Sylvie
Publicado 2014

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein

por Budigi, Yadunanda, Ong, Eugenia Z., Robinson, Luke N., Ong, Li Ching, Rowley, Kirk J., Winnett, Alexander, Tan, Hwee Cheng, Hobbie, Sven, Shriver, Zachary, Babcock, Gregory J., Alonso, Sylvie, Ooi, Eng Eong
Publicado 2018

Antibody-Dependent Dengue Virus Entry Modulates Cell Intrinsic Responses for Enhanced Infection

por Chan, Candice Y. Y., Low, John Zhong Heng, Gan, Esther Shuyi, Ong, Eugenia Ziying, Zhang, Summer Li-Xin, Tan, Hwee Cheng, Chai, Xiaoran, Ghosh, Sujoy, Ooi, Eng Eong, Chan, Kuan Rong
Publicado 2019