Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

por Ho, Peh Joo, Tan, Iain BeeHuat, Chong, Dawn Qingqing, Khor, Chiea Chuen, Yuan, Jian-Min, Koh, Woon-Puay, Dorajoo, Rajkumar, Li, Jingmei
Publicado 2023

Recommendations to improve the clinical adoption of NGS‐based cancer diagnostics in Singapore

por Tan, David Shao‐Peng, Tan, Daniel Shao‐Weng, Tan, Iain Bee Huat, Yan, Benedict, Choo, Su Pin, Chng, Wee Joo, Hwang, William Ying Khee
Publicado 2020

The distinct clinical trajectory, metastatic sites, and immunobiology of microsatellite-instability-high cancers

por Han, Shuting, Chok, Aik Yong, Peh, Daniel Yang Yao, Ho, Joshua Zhi-Ming, Tan, Emile Kwong Wei, Koo, Si-Lin, Tan, Iain Bee-Huat, Ong, Johnny Chin-Ann
Publicado 2022

Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction

por Low, Joo-Leng, Du, Weina, Gocha, Tenzin, Oguz, Gokce, Zhang, Xiaoqian, Chen, Ming Wei, Masirevic, Srdan, Yim, Daniel Guo Rong, Tan, Iain Bee Huat, Ramasamy, Adaikalavan, Fan, Hao, DasGupta, Ramanuj
Publicado 2021

The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity

por Ahmed, Syed Moiz, Ramani, Priya Dharshana, Wong, Stephen Qi Rong, Zhao, Xiaodan, Ivanyi-Nagy, Roland, Leong, Tang Choong, Chua, Clarinda, Li, Zhizhong, Hentze, Hannes, Tan, Iain BeeHuat, Yan, Jie, DasGupta, Ramanuj, Dröge, Peter
Publicado 2019

CD30(+)OX40(+) Treg is associated with improved overall survival in colorectal cancer

por Lam, Jian Hang, Hong, Michelle, Koo, Si-Lin, Chua, Clarinda Wei Ling, Lim, Kah Ling, Wee, Felicia, Wan, Wei Keat, Leow, Wei Qiang, Yeo, Joo Guan, Tan, Iain Bee Huat, Yeong, Joe, Lim, Tony Kiat Hon, Lim, Tong Seng
Publicado 2021

Recommended testing algorithms for NTRK gene fusions in pediatric and selected adult cancers: Consensus of a Singapore Task Force

por Lim, Kiat Hon Tony, Kong, Hwai Loong, Chang, Kenneth Tou En, Tan, Daniel Shao Weng, Tan, Iain Bee Huat, Mohamad, Farid, Soh, Shui Yen, Pang, Brendan Nghee‐Kheem, Soo, Ross Andrew, Choo, Su Pin, Hsieh, Wen‐Son, Aung, LeLe
Publicado 2021

Germline Pathogenic Variants in Homologous Recombination and DNA Repair Genes in an Asian Cohort of Young-Onset Colorectal Cancer

por Toh, Ming Ren, Chiang, Jian Bang, Chong, Siao Ting, Chan, Sock Hoai, Ishak, Nur Diana Binte, Courtney, Eliza, Lee, Wei Hao, Syed Abdillah Al, Syed Muhammad Fahmy Bin, Carson Allen, John, Lim, Kiat Hon, Davila, Sonia, Tan, Patrick, Lim, Weng Khong, Tan, Iain Bee Huat, Ngeow, Joanne
Publicado 2018

DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death

por Low, Heng Boon, Wong, Zhen Lim, Wu, Bangyuan, Kong, Li Ren, Png, Chin Wen, Cho, Yik-Lam, Li, Chun-Wei, Xiao, Fengchun, Xin, Xuan, Yang, Henry, Loo, Jia Min, Lee, Fiona Yi Xin, Tan, Iain Bee Huat, DasGupta, Ramanuj, Shen, Han-Ming, Schwarz, Herbert, Gascoigne, Nicholas R. J., Goh, Boon Cher, Xu, Xiaohong, Zhang, Yongliang
Publicado 2021

Inferring cancer disease response from radiology reports using large language models with data augmentation and prompting

por Tan, Ryan Shea Ying Cong, Lin, Qian, Low, Guat Hwa, Lin, Ruixi, Goh, Tzer Chew, Chang, Christopher Chu En, Lee, Fung Fung, Chan, Wei Yin, Tan, Wei Chong, Tey, Han Jieh, Leong, Fun Loon, Tan, Hong Qi, Nei, Wen Long, Chay, Wen Yee, Tai, David Wai Meng, Lai, Gillianne Geet Yi, Cheng, Lionel Tim-Ee, Wong, Fuh Yong, Chua, Matthew Chin Heng, Chua, Melvin Lee Kiang, Tan, Daniel Shao Weng, Thng, Choon Hua, Tan, Iain Bee Huat, Ng, Hwee Tou
Publicado 2023

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

por Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
Publicado 2019

Author Correction: PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

por Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
Publicado 2021