Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis

por Tan, Mingjia, Li, Hua, Sun, Yi
Publicado 2013

Inactivation of Sag/Rbx2/Roc2 E3 Ubiquitin Ligase Triggers Senescence and Inhibits Kras-Induced Immortalization

por Tan, Mingjia, Li, Hua, Sun, Yi
Publicado 2015

The p21-Dependent Radiosensitization of Human Breast Cancer Cells by MLN4924, an Investigational Inhibitor of NEDD8 Activating Enzyme

por Yang, Dong, Tan, Mingjia, Wang, Gongxian, Sun, Yi
Publicado 2012

Inactivation of SAG E3 Ubiquitin Ligase Blocks Embryonic Stem Cell Differentiation and Sensitizes Leukemia Cells to Retinoid Acid

por Tan, Mingjia, Li, Yun, Yang, Ruiguo, Xi, Ning, Sun, Yi
Publicado 2011

SAG/RBX2 E3 ligase complexes with UBCH10 and UBE2S E2s to ubiquitylate β-TrCP1 via K11-linkage for degradation

por Kuang, Peng, Tan, Mingjia, Zhou, Weihua, Zhang, Qiang, Sun, Yi
Publicado 2016

Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis

por Tan, Mingjia, Xu, Jie, Siddiqui, Javed, Feng, Felix, Sun, Yi
Publicado 2016

Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2–MRN–ATM axes

por Zhao, Yongchao, Tan, Mingjia, Liu, Xia, Xiong, Xiufang, Sun, Yi
Publicado 2018

Inactivation of SAG or ROC1 E3 Ligase Inhibits Growth and Survival of Renal Cell Carcinoma Cells: Effect of BIM()

por Wang, Yu, Tan, Mingjia, Li, Hua, Li, Haomin, Sun, Yi
Publicado 2019

FBXW2 suppresses migration and invasion of lung cancer cells via promoting β-catenin ubiquitylation and degradation

por Yang, Fei, Xu, Jie, Li, Hua, Tan, Mingjia, Xiong, Xiufang, Sun, Yi
Publicado 2019

Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras–PDAC model

por Zhang, Qiang, Wei, Dongping, Tan, Mingjia, Li, Haomin, Morgan, Meredith A., Sun, Yi
Publicado 2020

Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1

por Mao, Hongmei, Tang, Zaiming, Li, Hua, Sun, Bo, Tan, Mingjia, Fan, Shaohua, Zhu, Yuan, Sun, Yi
Publicado 2019

SAG/RBX2 E3 Ubiquitin Ligase Differentially Regulates Inflammatory Responses of Myeloid Cell Subsets

por Xiong, Xiufang, Mathewson, Nathan D., Li, Hua, Tan, Mingjia, Fujiwara, Hideaki, Li, Haomin, Reddy, Pavan, Sun, Yi
Publicado 2018

Interleukin‐6/signal transducer and activator of transcription 3 promotes prostate cancer resistance to androgen deprivation therapy via regulating pituitary tumor transforming gen...

por Huang, Shengquan, Liu, Qian, Liao, Qianjin, Wu, Qingjian, Sun, Bishao, Yang, Zhenxing, Hu, Xiaoyan, Tan, Mingjia, Li, Longkun
Publicado 2018

Increased Piezo1 channel activity in interstitial Cajal-like cells induces bladder hyperactivity by functionally interacting with NCX1 in rats with cyclophosphamide-induced cystiti...

por Liu, Qian, Sun, Bishao, Zhao, Jiang, Wang, Qingqing, An, Fan, Hu, Xiaoyan, Yang, Zhenxing, Xu, Jie, Tan, Mingjia, Li, Longkun
Publicado 2018

The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor

por Xu, Jie, Zhou, Weihua, Yang, Fei, Chen, Guoan, Li, Haomin, Zhao, Yongchao, Liu, Pengyuan, Li, Hua, Tan, Mingjia, Xiong, Xiufang, Sun, Yi
Publicado 2017

Neddylation inactivation represses androgen receptor transcription and inhibits growth, survival and invasion of prostate cancer cells

por Zhou, Xiaochen, Han, Sumin, Wilder-Romans, Kari, Sun, Grace Y., Zhu, Hong, Liu, Xiaoqiang, Tan, Mingjia, Wang, Gongxian, Feng, Felix Y., Sun, Yi
Publicado 2020