Dysregulation of the IFN-γ-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia

por Kulling, Paige M., Olson, Kristine C., Hamele, Cait E., Toro, Mariella F., Tan, Su-Fern, Feith, David J., Loughran, Thomas P.
Publicado 2018

The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia

por Annageldiyev, Charyguly, Gowda, Krishne, Patel, Trupti, Bhattacharya, Priyanjali, Tan, Su-Fern, Iyer, Soumya, Desai, Dhimant, Dovat, Sinisa, Feith, David J., Loughran, Thomas P., Amin, Shantu, Claxton, David, Sharma, Arati
Publicado 2020

Pan-tissue mitochondrial phenotyping reveals lower OXPHOS expression and function across cancer types

por Boykov, Ilya N., Montgomery, McLane M., Hagen, James T., Aruleba, Raphael T., McLaughlin, Kelsey L., Coalson, Hannah S., Nelson, Margaret A., Pereyra, Andrea S., Ellis, Jessica M., Zeczycki, Tonya N., Vohra, Nasreen A., Tan, Su-Fern, Cabot, Myles C., Fisher-Wellman, Kelsey H.
Publicado 2023

The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia

por Annageldiyev, Charyguly, Tan, Su-Fern, Thakur, Shreya, Dhanyamraju, Pavan Kumar, Ramisetti, Srinivasa R., Bhadauria, Preeti, Schick, Jacob, Zeng, Zheng, Sharma, Varun, Dunton, Wendy, Dovat, Sinisa, Desai, Dhimant, Zheng, Hong, Feith, David J., Loughran, Thomas P., Amin, Shantu, Sharma, Arun K., Claxton, David, Sharma, Arati
Publicado 2020

Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia

por Khokhlatchev, Andrei V., Sharma, Arati, Deering, Tye G., Shaw, Jeremy J. P., Costa‐Pinheiro, Pedro, Golla, Upendarrao, Annageldiyev, Charyguly, Cabot, Myles C., Conaway, Mark R., Tan, Su‐Fern, Ung, Johnson, Feith, David J., Loughran, Thomas P., Claxton, David F., Fox, Todd E., Kester, Mark
Publicado 2022

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

por Paudel, B. Bishal, Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Shaw, Jeremy, Dunton, Wendy, Lee, Irene, Sharma, Arati, Viny, Aaron D., Barth, Brian M., Tallman, Martin S., Cabot, Myles, Garrett-Bakelman, Francine E., Levine, Ross L., Kester, Mark, Claxton, David, Feith, David J., Janes, Kevin A., Loughran, Thomas P.
Publicado 2023

Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloi...

por Fisher-Wellman, Kelsey H., Kassai, Miki, Hagen, James T., Neufer, P. Darrell, Kester, Mark, Loughran, Thomas P., Chalfant, Charles E., Feith, David J., Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Fabrias, Gemma, Abad, Jose’ Luis, Sharma, Arati, Golla, Upendarrao, Claxton, David F., Shaw, Jeremy J. P., Bhowmick, Debajit, Cabot, Myles C.
Publicado 2023

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

por Tan, Su-Fern, Liu, Xin, Fox, Todd E., Barth, Brian M., Sharma, Arati, Turner, Stephen D., Awwad, Andy, Dewey, Alden, Doi, Kenichiro, Spitzer, Barbara, Shah, Mithun Vinod, Morad, Samy A.F., Desai, Dhimant, Amin, Shantu, Zhu, Junjia, Liao, Jason, Yun, Jong, Kester, Mark, Claxton, David F., Wang, Hong-Gang, Cabot, Myles C., Schuchman, Edward H., Levine, Ross L., Feith, David J., Loughran, Thomas P.
Publicado 2016