Novel therapeutic avenues in triple-negative breast cancer: PI3K/AKT inhibition, androgen receptor blockade, and beyond

por Chan, Jack J., Tan, Tira J. Y., Dent, Rebecca A.
Publicado 2019

The impact of Irritable Bowel Syndrome on health-related quality of life: a Singapore perspective

por Wang, Yu Tien, Lim, Hwee Yong, Tai, David, Krishnamoorthy, Thinesh L, Tan, Tira, Barbier, Sylvaine, Thumboo, Julian
Publicado 2012

Candida Endophthalmitis Treated Successfully With Isavuconazole: A Case Report

por Sng, Edwin Chong Yu, Tan, Ai Ling, Zhou, Peijun Yvonne, Tan, Tira J, Waduthantri, Samanthila, Chee, Soon-Phaik, Tan, Ban Hock
Publicado 2021

Identification of Comprehensive Geriatric Assessment Based Risk Factors for Malnutrition in Elderly Asian Cancer Patients

por Tan, Tira, Ong, Whee Sze, Rajasekaran, Tanujaa, Nee Koo, Khai, Chan, Li Li, Poon, Donald, Roy Chowdhury, Anupama, Krishna, Lalit, Kanesvaran, Ravindran
Publicado 2016

IMPACT OF SUBSIDY ON THE USE OF PERSONALIZED MEDICINE IN BREAST CANCER

por Chen, Cynthia, Lim, Jue Tao, Lim, Swee Ho, Tan, Ern Yu, Tan, Veronique Kiak Mien, Tan, Su Ming, Tan, Tira, Hartman, Mikael
Publicado 2022

External validation of the first prognostic nomogram for older adults with cancer

por Tay, Yu Ling, Ong, Whee Sze, Liew, Sherilyn Zi Hui, Chowdhury, Anupama Roy, Chan, Johan, Ramalingam, Mothi Babu, Rajasekaran, Tanujaa, Tan, Tira J., Krishna, Lalit, Lai, Olive, Chow, Agnes Lai Yin, Chen, Simon, Kanesvaran, Ravindran
Publicado 2023

First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid...

por Piha-Paul, Sarina A, Geva, Ravit, Tan, Tira J, Lim, Darren WT, Hierro, Cinta, Doi, Toshikiko, Rahma, Osama, Lesokhin, Alexander, Luke, Jason John, Otero, Javier, Nardi, Lisa, Singh, Angad, Xyrafas, Alexandros, Chen, Xinhui, Mataraza, Jennifer, Bedard, Philippe L
Publicado 2021

A study protocol for HEalth-Related quality of life-intervention in survivors of Breast and other cancers experiencing cancer-related fatigue using TraditionAL Chinese Medicine: th...

por Yap, Ning Yi, Loo, Wei Sheng, Zheng, Huang Fang, Tan, Quan Ming, Tan, Tze Kiat, Quek, Leona Yan Peng, Tan, Chia Jie, Toh, Yi Long, Ng, Chiu Chin, Ang, Seng Kok, Tan, Veronique Kiak Mien, Ho, Han Kiat, Chew, Lita, Loh, Kiley Wei-Jen, Tan, Tira Jing Ying, Chan, Alexandre
Publicado 2020

Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

por Zhu, Guanhua, Guo, Yu A., Ho, Danliang, Poon, Polly, Poh, Zhong Wee, Wong, Pui Mun, Gan, Anna, Chang, Mei Mei, Kleftogiannis, Dimitrios, Lau, Yi Ting, Tay, Brenda, Lim, Wan Jun, Chua, Clarinda, Tan, Tira J., Koo, Si-Lin, Chong, Dawn Q., Yap, Yoon Sim, Tan, Iain, Ng, Sarah, Skanderup, Anders J.
Publicado 2021

Effects of housing value and medical subsidy on treatment and outcomes of breast cancer patients in Singapore: A retrospective cohort study

por Wong, Fuh Yong, Wong, Ru Xin, Zhou, Siqin, Ong, Whee Sze, Pek, Pin Pin, Yap, Yoon-Sim, Tan, Benita Kiat Tee, Ngeow, Joanne Yuen Yie, Tan, Veronique Kiak Mien, Sim, Yirong, Tan, Su-Ming, Lim, Swee Ho, Madhukumar, Preetha, Tan, Tira Jing Ying, Loh, Kiley Wei-Jen, Ong, Marcus Eng Hock, Wong, Ting Hway
Publicado 2020

Impact of Cryotherapy on Sensory, Motor, and Autonomic Neuropathy in Breast Cancer Patients Receiving Paclitaxel: A Randomized, Controlled Trial

por Ng, Ding Quan, Tan, Chia Jie, Soh, Boon Chua, Tan, Mabel May Leng, Loh, Soon Yue, Tan, Yam Eng, Ong, Hui Hui, Teng, Peggy Pei Chee, Chan, Jack Junjie, Chay, Wen Yee, Lee, Joycelyn, Lai, Gillianne, Beh, Sok Yuen, Tan, Tira Jing Ying, Yap, Yoon Sim, Lee, Guek Eng, Wong, Mabel, Dent, Rebecca, Lo, Yew Long, Chan, Alexandre, Loh, Kiley Wei-Jen
Publicado 2020

Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy

por Tan, Chia Jie, Lim, Sheree Wan Ting, Toh, Yi Long, Ng, Terence, Yeo, Angie, Shwe, Maung, Foo, Koon Mian, Chu, Pat, Jain, Amit, Koo, Si-Lin, Dent, Rebecca A., Ng, Raymond Chee Hui, Yap, Yoon Sim, Lim, Elaine H., Loh, Kiley Wei-Jen, Chay, Wen Yee, Lee, Guek Eng, Tan, Tira Jing Ying, Beh, Sok Yuen, Wong, Mabel, Chan, Jack Junjie, Khor, Chiea Chuen, Ho, Han Kiat, Chan, Alexandre
Publicado 2018

Complementary Sequential Circulating Tumor Cell (CTC) and Cell-Free Tumor DNA (ctDNA) Profiling Reveals Metastatic Heterogeneity and Genomic Changes in Lung Cancer and Breast Cance...

por Kong, Say Li, Liu, Xingliang, Tan, Swee Jin, Tai, Joyce A., Phua, Ler Yee, Poh, Huay Mei, Yeo, Trifanny, Chua, Yong Wei, Haw, Yu Xuan, Ling, Wen Huan, Ng, Raymond Chee Hui, Tan, Tira J., Loh, Kiley Wei Jen, Tan, Daniel Shao-Weng, Ng, Quan Sing, Ang, Mei Kim, Toh, Chee Keong, Lee, Yi Fang, Lim, Chwee Teck, Lim, Tony Kiat Hon, Hillmer, Axel M., Yap, Yoon Sim, Lim, Wan-Teck
Publicado 2021

A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma

por Tan, Tira J., Ang, W. X. Gladys, Wang, Who-Whong, Chong, Hui-Shan, Tan, Sze Huey, Cheong, Rachael, Chia, John Whay-Kuang, Syn, Nicholas L., Shuen, Wai Ho, Ba, Rebecca, Kaliaperumal, Nivashini, Au, Bijin, Hopkins, Richard, Li, Xinhua, Tan, Aaron C., Seet, Amanda O. L., Connolly, John E., Arkachaisri, Thaschawee, Chew, Valerie, Lajam, Ahmad bin Mohamed, Guo, Dianyan, Chew, Marvin Z. W., Wasser, Martin, Kumar, Pavanish, Albani, Salvatore, Toh, Han Chong
Publicado 2022

A systematic review and meta-analysis of individual patient data on the impact of the BIM deletion polymorphism on treatment outcomes in epidermal growth factor receptor mutant lun...

por Soh, Sheila X., Siddiqui, Fahad J., Allen, John C., Kim, Go Woon, Lee, Jae Cheol, Yatabe, Yasushi, Soda, Manabu, Mano, Hiroyuki, Soo, Ross A., Chin, Tan-Min, Ebi, Hiromichi, Yano, Seiji, Matsuo, Keitaro, Niu, Xiaomin, Lu, Shun, Isobe, Kazutoshi, Lee, Jih-Hsiang, Yang, James C., Zhao, Mingchuan, Zhou, Caicun, Lee, June-Koo, Lee, Se-Hoon, Lee, Ji Yun, Ahn, Myung-Ju, Tan, Tira J., Tan, Daniel S., Tan, Eng-Huat, Ong, S. Tiong, Lim, Wan-Teck
Publicado 2017

A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in...

por Ho, Jingshan, Heong, Valerie, Peng Yong, Wei, Soo, Ross, Ean Chee, Cheng, Wong, Andrea, Sundar, Raghav, Liang Thian, Yee, Gopinathan, Anil, Yan Pang, Mei, Koe, Priscillia, Nathan Jeraj, Santhiay, Pyar Soe, Phyu, Yar Soe, Mu, Tang, Tiffany, Ng, Matthew C.H., Tai, David W.M., Tan, Tira J.Y., Xu, Hongmei, Chang, Hua, Landesman, Yosef, Shah, Jatin, Shacham, Sharon, Chin Lee, Soo, Tan, Daniel S.W., Cher Goh, Boon, Tan, David S.P.
Publicado 2022

Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

por Loo, Ser Yue, Toh, Li Ping, Xie, William Haowei, Pathak, Elina, Tan, Wilson, Ma, Siming, Lee, May Yin, Shatishwaran, S., Yeo, Joanna Zhen Zhen, Yuan, Ju, Ho, Yin Ying, Peh, Esther Kai Lay, Muniandy, Magendran, Torta, Federico, Chan, Jack, Tan, Tira J., Sim, Yirong, Tan, Veronique, Tan, Benita, Madhukumar, Preetha, Yong, Wei Sean, Ong, Kong Wee, Wong, Chow Yin, Tan, Puay Hoon, Yap, Yoon Sim, Deng, Lih-Wen, Dent, Rebecca, Foo, Roger, Wenk, Markus R., Lee, Soo Chin, Ho, Ying Swan, Lim, Elaine Hsuen, Tam, Wai Leong
Publicado 2021

Association between Breast Cancer Polygenic Risk Score and Chemotherapy-Induced Febrile Neutropenia: Null Results

por Ong, Seeu Si, Ho, Peh Joo, Khng, Alexis Jiaying, Lim, Elaine Hsuen, Wong, Fuh Yong, Tan, Benita Kiat-Tee, Lim, Swee Ho, Tan, Ern Yu, Tan, Su-Ming, Tan, Veronique Kiak Mien, Dent, Rebecca, Tan, Tira Jing Ying, Ngeow, Joanne, Madhukumar, Preetha, Hamzah, Julie Liana Bte, Sim, Yirong, Lim, Geok Hoon, Pang, Jinnie Siyan, Alcantara, Veronica Siton, Chan, Patrick Mun Yew, Chen, Juliana Jia Chuan, Kuah, Sherwin, Seah, Jaime Chin Mui, Buhari, Shaik Ahmad, Tang, Siau Wei, Ng, Celene Wei Qi, Li, Jingmei, Hartman, Mikael
Publicado 2022