Gastrointestinal Peptides as Therapeutic Targets to Mitigate Obesity and Metabolic Syndrome

por Alexiadou, Kleopatra, Tan, Tricia M-M.
Publicado 2020

No Guts, No Loss: Toward the Ideal Treatment for Obesity in the Twenty-First Century

por Hope, David C. D., Tan, Tricia M. M., Bloom, Stephen R.
Publicado 2018

Striking the Balance: GLP-1/Glucagon Co-Agonism as a Treatment Strategy for Obesity

por Hope, David C. D., Vincent, Matthew L., Tan, Tricia M. M.
Publicado 2021

The acute effect of glucagon on components of energy balance and glucose homoeostasis in adults without diabetes: a systematic review and meta-analysis

por Frampton, James, Izzi-Engbeaya, Chioma, Salem, Victoria, Murphy, Kevin G., Tan, Tricia M., Chambers, Edward S.
Publicado 2022

Beyond Weight Loss: Establishing a Postbariatric Surgery Patient Support Group—What Do Patients Want?

por Hameed, Saira, Salem, Victoria, Tan, Tricia M., Collins, Alma, Shah, Krishna, Scholtz, Samantha, Ahmed, Ahmed R., Chahal, Harvinder
Publicado 2018

A legacy of tinnitus: multiple head and neck paragangliomas

por Tan, Tricia M.M, Hatfield, Emma C.I, Thakker, Rajesh V, Maher, Eamonn R, Meeran, Karim, Martin, Niamh M, Turner, Jeremy J
Publicado 2009

A glucagon analogue decreases body weight in mice via signalling in the liver

por Hinds, Charlotte E., Owen, Bryn M., Hope, David C. D., Pickford, Philip, Jones, Ben, Tan, Tricia M., Minnion, James S., Bloom, Stephen R.
Publicado 2021

RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

por Cegla, Jaimini, Jones, Ben J., Gardiner, James V., Hodson, David J., Marjot, Thomas, McGlone, Emma R., Tan, Tricia M., Bloom, Stephen R.
Publicado 2017

The Metabolomic Effects of Tripeptide Gut Hormone Infusion Compared to Roux-en-Y Gastric Bypass and Caloric Restriction

por Jones, Ben, Sands, Caroline, Alexiadou, Kleopatra, Minnion, James, Tharakan, George, Behary, Preeshila, Ahmed, Ahmed R, Purkayastha, Sanjay, Lewis, Matthew R, Bloom, Stephen, Li, Jia V, Tan, Tricia M
Publicado 2021

The benefit of dexamethasone in patients with COVID‐19 infection is preserved in patients with diabetes

por Eng, Pei Chia, Distaso, Walter, Durreshahwar, Hashmi, Shaikhali, Yusuf, Narendranathan, Divani, Cassin‐Scott, Rebecca, Misra, Shivani, Hill, Neil E., Tharakan, George, Oliver, Nick S., Tan, Tricia M., Izzi‐Engbeaya, Chioma, Salem, Victoria
Publicado 2022

Weight Loss by Low-Calorie Diet Versus Gastric Bypass Surgery in People With Diabetes Results in Divergent Brain Activation Patterns: A Functional MRI Study

por Salem, Victoria, Demetriou, Lysia, Behary, Preeshila, Alexiadou, Kleopatra, Scholtz, Samantha, Tharakan, George, Miras, Alexander D., Purkayastha, Sanjay, Ahmed, Ahmed R., Bloom, Stephen R., Wall, Matthew B., Dhillo, Waljit S., Tan, Tricia M.-M.
Publicado 2021

Determining the role of novel metabolic pathways in driving intracranial pressure reduction after weight loss

por Alimajstorovic, Zerin, Mitchell, James L, Yiangou, Andreas, Hancox, Thomas, Southam, Andrew D, Grech, Olivia, Ottridge, Ryan, Winder, Catherine L, Tahrani, Abd A, Tan, Tricia M, Mollan, Susan P, Dunn, Warwick B, Sinclair, Alexandra J
Publicado 2023

Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1

por Marzook, Amaara, Chen, Shiqian, Pickford, Phil, Lucey, Maria, Wang, Yifan, Corrêa Jr, Ivan R., Broichhagen, Johannes, Hodson, David J., Salem, Victoria, Rutter, Guy A., Tan, Tricia M., Bloom, Stephen R., Tomas, Alejandra, Jones, Ben
Publicado 2021

Combination of Peptide YY(3–36) with GLP-1(7–36 amide) Causes an Increase in First-Phase Insulin Secretion after IV Glucose

por Tan, Tricia M., Salem, Victoria, Troke, Rachel C., Alsafi, Ali, Field, Benjamin C. T., De Silva, Akila, Misra, Shivani, Baynes, Kevin C. R., Donaldson, Mandy, Minnion, James, Ghatei, Mohammad A., Godsland, Ian F., Bloom, Stephen R.
Publicado 2014

Coadministration of Glucagon-Like Peptide-1 During Glucagon Infusion in Humans Results in Increased Energy Expenditure and Amelioration of Hyperglycemia

por Tan, Tricia M., Field, Benjamin C.T., McCullough, Katherine A., Troke, Rachel C., Chambers, Edward S., Salem, Victoria, Gonzalez Maffe, Juan, Baynes, Kevin C.R., De Silva, Akila, Viardot, Alexander, Alsafi, Ali, Frost, Gary S., Ghatei, Mohammad A., Bloom, Stephen R.
Publicado 2013

Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study

por Alexiadou, Kleopatra, Cuenco, Joyceline, Howard, James, Wewer Albrechtsen, Nicolai Jacob, Ilesanmi, Ibiyemi, Kamocka, Anna, Tharakan, George, Behary, Preeshila, Bech, Paul R, Ahmed, Ahmed R, Purkayastha, Sanjay, Wheller, Robert, Fleuret, Matthieu, Holst, Jens Juul, Bloom, Stephen R, Khoo, Bernard, Tan, Tricia M-M
Publicado 2020

Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

por Pickford, Phil, Lucey, Maria, Rujan, Roxana-Maria, McGlone, Emma Rose, Bitsi, Stavroula, Ashford, Fiona B., Corrêa, Ivan R., Hodson, David J., Tomas, Alejandra, Deganutti, Giuseppe, Reynolds, Christopher A., Owen, Bryn M., Tan, Tricia M., Minnion, James, Jones, Ben, Bloom, Stephen R.
Publicado 2021

Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss

por Hope, David C.D., Hinds, Charlotte E., Lopes, Tatiana, Vincent, Matthew L., Shrewsbury, Jed V., Yu, Arthur T.C., Davies, Iona, Scott, Rebecca, Jones, Ben, Murphy, Kevin G., Minnion, James S., Sardini, Alessandro, Carling, David, Lutz, Thomas A., Bloom, Stephen R., Tan, Tricia M.M., Owen, Bryn M.
Publicado 2022

Adverse outcomes in COVID-19 and diabetes: a retrospective cohort study from three London teaching hospitals

por Izzi-Engbeaya, Chioma, Distaso, Walter, Amin, Anjali, Yang, Wei, Idowu, Oluwagbemiga, Kenkre, Julia S, Shah, Ronak J, Woin, Evelina, Shi, Christine, Alavi, Nael, Bedri, Hala, Brady, Niamh, Blackburn, Sophie, Leczycka, Martina, Patel, Sanya, Sokol, Elizaveta, Toke-Bjolgerud, Edward, Qayum, Ambreen, Abdel-Malek, Mariana, Hope, David C D, Oliver, Nick S, Bravis, Vasiliki, Misra, Shivani, Tan, Tricia M, Hill, Neil E, Salem, Victoria
Publicado 2021

GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

por Lagou, Vasiliki, Jiang, Longda, Ulrich, Anna, Zudina, Liudmila, González, Karla Sofia Gutiérrez, Balkhiyarova, Zhanna, Faggian, Alessia, Maina, Jared G., Chen, Shiqian, Todorov, Petar V., Sharapov, Sodbo, David, Alessia, Marullo, Letizia, Mägi, Reedik, Rujan, Roxana-Maria, Ahlqvist, Emma, Thorleifsson, Gudmar, Gao, Ηe, Εvangelou, Εvangelos, Benyamin, Beben, Scott, Robert A., Isaacs, Aaron, Zhao, Jing Hua, Willems, Sara M., Johnson, Toby, Gieger, Christian, Grallert, Harald, Meisinger, Christa, Müller-Nurasyid, Martina, Strawbridge, Rona J., Goel, Anuj, Rybin, Denis, Albrecht, Eva, Jackson, Anne U., Stringham, Heather M., Corrêa, Ivan R., Farber-Eger, Eric, Steinthorsdottir, Valgerdur, Uitterlinden, André G., Munroe, Patricia B., Brown, Morris J., Schmidberger, Julian, Holmen, Oddgeir, Thorand, Barbara, Hveem, Kristian, Wilsgaard, Tom, Mohlke, Karen L., Wang, Zhe, Shmeliov, Aleksey, den Hoed, Marcel, Loos, Ruth J. F., Kratzer, Wolfgang, Haenle, Mark, Koenig, Wolfgang, Boehm, Bernhard O., Tan, Tricia M., Tomas, Alejandra, Salem, Victoria, Barroso, Inês, Tuomilehto, Jaakko, Boehnke, Michael, Florez, Jose C., Hamsten, Anders, Watkins, Hugh, Njølstad, Inger, Wichmann, H.-Erich, Caulfield, Mark J., Khaw, Kay-Tee, van Duijn, Cornelia M., Hofman, Albert, Wareham, Nicholas J., Langenberg, Claudia, Whitfield, John B., Martin, Nicholas G., Montgomery, Grant, Scapoli, Chiara, Tzoulaki, Ioanna, Elliott, Paul, Thorsteinsdottir, Unnur, Stefansson, Kari, Brittain, Evan L., McCarthy, Mark I., Froguel, Philippe, Sexton, Patrick M., Wootten, Denise, Groop, Leif, Dupuis, Josée, Meigs, James B., Deganutti, Giuseppe, Demirkan, Ayse, Pers, Tune H., Reynolds, Christopher A., Aulchenko, Yurii S., Kaakinen, Marika A., Jones, Ben, Prokopenko, Inga
Publicado 2023