The Efficacy and Pharmacological Mechanism of Zn(7)MT3 to Protect against Alzheimer’s Disease

por Xu, Wei, Xu, Qiming, Cheng, Hao, Tan, Xiangshi
Publicado 2017

The Δ33-35 Mutant α-Domain Containing β-Domain-Like M(3)S(9) Cluster Exhibits the Function of α-Domain with M(4)S(11) Cluster in Human Growth Inhibitory Factor

por Bao, Qingui, Ding, Zhichun, Huang, Zhong-Xian, Tan, Xiangshi
Publicado 2010

Development of Novel Ecto-Nucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Tumor Immunotherapy

por Wang, Xiang, Lu, Xing, Yan, Daojing, Zhou, Yajun, Tan, Xiangshi
Publicado 2022

Potent Therapeutic Strategies for COVID-19 with Single-Domain Antibody Immunoliposomes Neutralizing SARS-CoV-2 and Lip/cGAMP Enhancing Protective Immunity

por Zhou, Yajun, Lu, Xing, Wang, Xiaoqing, Ying, Tianlei, Tan, Xiangshi
Publicado 2023

Anti-triple-negative breast cancer metastasis efficacy and molecular mechanism of the STING agonist for innate immune pathway

por Lu, Xing, Wang, Xiang, Cheng, Hao, Wang, Xiaoqing, Liu, Chang, Tan, Xiangshi
Publicado 2023

Activation of STING by cGAMP Regulates MDSCs to Suppress Tumor Metastasis via Reversing Epithelial-Mesenchymal Transition

por Cheng, Hao, Xu, Qiming, Lu, Xing, Yuan, Hong, Li, Tiejun, Zhang, Yuefan, Tan, Xiangshi
Publicado 2020

Spiro-Oxindole Skeleton Compounds Are Efficient Inhibitors for Indoleamine 2,3-Dioxygenase 1: An Attractive Target for Tumor Immunotherapy

por Yan, Daojing, Xu, Jiakun, Wang, Xiang, Zhang, Jiaxing, Zhao, Gang, Lin, Yingwu, Tan, Xiangshi
Publicado 2022

Self-oxidation of cysteine to sulfinic acid in an engineered T67C myoglobin: structure and reactivity

por Dai, Wei, Yuan, Hong, Wang, Xiao-Juan, Gao, Shu-Qin, Tan, Xiangshi, Lin, Ying-Wu
Publicado 2023

Regulating the Coordination State of a Heme Protein by a Designed Distal Hydrogen-Bonding Network

por Du, Jun-Fang, Li, Wei, Li, Lianzhi, Wen, Ge-Bo, Lin, Ying-Wu, Tan, Xiangshi
Publicado 2015

Functional Conversion of Acetyl-Coenzyme a Synthase to a Nickel Superoxide Dismutase via Rational Design of Coordination Microenvironment for the Ni(d)-Site

por Wei, Yaozhu, Zhou, Yajun, Yuan, Hong, Liu, Yi, Lin, Ying-Wu, Su, Jihu, Tan, Xiangshi
Publicado 2022

Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase

por Lan, Wenxian, Wang, Zhonghua, Yang, Zhongzheng, Ying, Tianlei, Zhang, Xu, Tan, Xiangshi, Liu, Maili, Cao, Chunyang, Huang, Zhong-Xian
Publicado 2014

Design and Engineering of an Efficient Peroxidase Using Myoglobin for Dye Decolorization and Lignin Bioconversion

por Guo, Wen-Jie, Xu, Jia-Kun, Wu, Sheng-Tao, Gao, Shu-Qin, Wen, Ge-Bo, Tan, Xiangshi, Lin, Ying-Wu
Publicado 2021

Probing the Molecular Mechanism of Human Soluble Guanylate Cyclase Activation by NO in vitro and in vivo

por Pan, Jie, Yuan, Hong, Zhang, Xiaoxue, Zhang, Huijuan, Xu, Qiming, Zhou, Yajun, Tan, Li, Nagawa, Shingo, Huang, Zhong-Xian, Tan, Xiangshi
Publicado 2017

Kinetic, Thermodynamic, and Crystallographic Studies of 2-Triazolylthioacetamides as Verona Integron-Encoded Metallo-β-Lactamase 2 (VIM-2) Inhibitor

por Xiang, Yang, Zhang, Yue-Juan, Ge, Ying, Zhou, Yajun, Chen, Cheng, Wahlgren, Weixiao Yuan, Tan, Xiangshi, Chen, Xi, Yang, Ke-Wu
Publicado 2020

Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response

por Li, Tiejun, Cheng, Hao, Yuan, Hong, Xu, Qiming, Shu, Chang, Zhang, Yuefan, Xu, Pengbiao, Tan, Jason, Rui, Yaocheng, Li, Pingwei, Tan, Xiangshi
Publicado 2016

Rational Design of Dual Active Sites in a Single Protein Scaffold: A Case Study of Heme Protein in Myoglobin

por Shu, Xiao‐Gang, Su, Ji‐Hu, Du, Ke‐Jie, You, Yong, Gao, Shu‐Qin, Wen, Ge‐Bo, Tan, Xiangshi, Lin, Ying‐Wu
Publicado 2016

Conformational Toggling of Yeast Iso-1-Cytochrome c in the Oxidized and Reduced States

por Lan, Wenxian, Wang, Zhonghua, Yang, Zhongzheng, Zhu, Jing, Ying, Tianlei, Jiang, Xianwang, Zhang, Xu, Wu, Houming, Liu, Maili, Tan, Xiangshi, Cao, Chunyang, Huang, Zhong-Xian
Publicado 2011