Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21

por Hussain, Ali, Voisin, Veronique, Poon, Stephanie, Karamboulas, Christina, Bui, Ngoc Hoang Bao, Meens, Jalna, Dmytryshyn, Julia, Ho, Victor W., Tang, Kwan Ho, Paterson, Joshua, Clarke, Blaise A., Bernardini, Marcus Q., Bader, Gary D., Neel, Benjamin G., Ailles, Laurie E.
Publicado 2020

Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC

por Tang, Kwan Ho, Li, Shuai, Khodadadi-Jamayran, Alireza, Jen, Jayu, Han, Han, Guidry, Kayla, Chen, Ting, Hao, Yuan, Fedele, Carmine, Zebala, John A., Maeda, Dean Y., Christensen, James G., Olson, Peter, Athanas, Argus, Loomis, Cynthia A., Tsirigos, Aristotelis, Wong, Kwok-Kin, Neel, Benjamin G.
Publicado 2022

SHP2 inhibition diminishes KRAS(G12C) cycling and promotes tumor microenvironment remodeling

por Fedele, Carmine, Li, Shuai, Teng, Kai Wen, Foster, Connor J.R., Peng, David, Ran, Hao, Mita, Paolo, Geer, Mitchell J., Hattori, Takamitsu, Koide, Akiko, Wang, Yubao, Tang, Kwan Ho, Leinwand, Joshua, Wang, Wei, Diskin, Brian, Deng, Jiehui, Chen, Ting, Dolgalev, Igor, Ozerdem, Ugur, Miller, George, Koide, Shohei, Wong, Kwok-Kin, Neel, Benjamin G.
Publicado 2020

Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

por Han, Han, Li, Shuai, Chen, Ting, Fitzgerald, Michael, Liu, Shengwu, Peng, Chengwei, Tang, Kwan Ho, Cao, Shougen, Chouitar, Johara, Wu, Jiansheng, Peng, David, Deng, Jiehui, Gao, Zhendong, Baker, Theresa E., Li, Fei, Zhang, Hua, Pan, Yuanwang, Ding, Hailin, Hu, Hai, Pyon, Val, Thakurdin, Cassandra, Papadopoulos, Eleni, Tang, Sittinon, Gonzalvez, Francois, Chen, Haiquan, Rivera, Victor M., Brake, Rachael, Vincent, Sylvie, Wong, Kwok-Kin
Publicado 2021