Loss of TSC1/TSC2 sensitizes immune checkpoint blockade in non–small cell lung cancer

por Huang, Qingyuan, Li, Fei, Hu, Hai, Fang, Zhaoyuan, Gao, Zhendong, Xia, Guozhan, Ng, Wai-Lung, Khodadadi-Jamayran, Alireza, Chen, Ting, Deng, Jiehui, Zhang, Hua, Almonte, Christina, Labbe, Kristen, Han, Han, Geng, Ke, Tang, Sittinon, Freeman, Gordon J., Li, Yuan, Chen, Haiquan, Wong, Kwok-Kin
Publicado 2022

Nemvaleukin alfa, a novel engineered IL-2 fusion protein, drives antitumor immunity and inhibits tumor growth in small cell lung cancer

por Pan, Yuanwang, Hao, Yuan, Han, Han, Chen, Ting, Ding, Hailin, Labbe, Kristen E, Shum, Elaine, Guidry, Kayla, Hu, Hai, Sherman, Fiona, Geng, Ke, Stephens, Janaye, Chafitz, Alison, Tang, Sittinon, Huang, Hsin-Yi, Peng, Chengwei, Almonte, Christina, Lopes, Jared E, Losey, Heather C, Winquist, Raymond J, Velcheti, Vamsidhar, Zhang, Hua, Wong, Kwok-Kin
Publicado 2022

Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

por Han, Han, Li, Shuai, Chen, Ting, Fitzgerald, Michael, Liu, Shengwu, Peng, Chengwei, Tang, Kwan Ho, Cao, Shougen, Chouitar, Johara, Wu, Jiansheng, Peng, David, Deng, Jiehui, Gao, Zhendong, Baker, Theresa E., Li, Fei, Zhang, Hua, Pan, Yuanwang, Ding, Hailin, Hu, Hai, Pyon, Val, Thakurdin, Cassandra, Papadopoulos, Eleni, Tang, Sittinon, Gonzalvez, Francois, Chen, Haiquan, Rivera, Victor M., Brake, Rachael, Vincent, Sylvie, Wong, Kwok-Kin
Publicado 2021

Targeting the Atf7ip–Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity

por Hu, Hai, Khodadadi-Jamayran, Alireza, Dolgalev, Igor, Cho, Hyunwoo, Badri, Sana, Chiriboga, Luis A., Zeck, Briana, Lopez De Rodas Gregorio, Miguel, Dowling, Catríona M., Labbe, Kristen, Deng, Jiehui, Chen, Ting, Zhang, Hua, Zappile, Paul, Chen, Ze, Ueberheide, Beatrix, Karatza, Angeliki, Han, Han, Ranieri, Michela, Tang, Sittinon, Jour, George, Osman, Iman, Sucker, Antje, Schadendorf, Dirk, Tsirigos, Aristotelis, Schalper, Kurt A., Velcheti, Vamsidhar, Huang, Hsin-yi, Jin, Yujuan, Ji, Hongbin, Poirier, John T., Li, Fei, Wong, Kwok-Kin
Publicado 2021