Germ cell specification and pluripotency in mammals: a perspective from early embryogenesis

por Irie, Naoko, Tang, Walfred W. C., Azim Surani, M.
Publicado 2014

A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

por Sybirna, Anastasiya, Tang, Walfred W. C., Pierson Smela, Merrick, Dietmann, Sabine, Gruhn, Wolfram H., Brosh, Ran, Surani, M. Azim
Publicado 2020

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

por Irie, Naoko, Weinberger, Leehee, Tang, Walfred W.C., Kobayashi, Toshihiro, Viukov, Sergey, Manor, Yair S., Dietmann, Sabine, Hanna, Jacob H., Surani, M. Azim
Publicado 2015

Esrrb Complementation Rescues Development of Nanog-Null Germ Cells

por Zhang, Man, Leitch, Harry G., Tang, Walfred W.C., Festuccia, Nicola, Hall-Ponsele, Elisa, Nichols, Jennifer, Surani, M. Azim, Smith, Austin, Chambers, Ian
Publicado 2018

Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis

por Ramos-Ibeas, Priscila, Sang, Fei, Zhu, Qifan, Tang, Walfred W. C., Withey, Sarah, Klisch, Doris, Wood, Liam, Loose, Matt, Surani, M. Azim, Alberio, Ramiro
Publicado 2019

Sequential enhancer state remodelling defines human germline competence and specification

por Tang, Walfred W.C., Castillo-Venzor, Aracely, Gruhn, Wolfram H., Kobayashi, Toshihiro, Penfold, Christopher A., Morgan, Michael D., Sun, Dawei, Irie, Naoko, Azim Surani, M.
Publicado 2022

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

por Tang, Walfred W.C., Dietmann, Sabine, Irie, Naoko, Leitch, Harry G., Floros, Vasileios I., Bradshaw, Charles R., Hackett, Jamie A., Chinnery, Patrick F., Surani, M. Azim
Publicado 2015

Epigenetic resetting in the human germ line entails histone modification remodeling

por Gruhn, Wolfram H., Tang, Walfred W.C., Dietmann, Sabine, Alves-Lopes, João P., Penfold, Christopher A., Wong, Frederick C. K., Ramakrishna, Navin B., Surani, M. Azim
Publicado 2023

Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage

por Zhu, Qifan, Sang, Fei, Withey, Sarah, Tang, Walfred, Dietmann, Sabine, Klisch, Doris, Ramos-Ibeas, Priscila, Zhang, Haixin, Requena, Cristina E., Hajkova, Petra, Loose, Matt, Surani, M. Azim, Alberio, Ramiro
Publicado 2021

Origin and segregation of the human germline

por Castillo-Venzor, Aracely, Penfold, Christopher A, Morgan, Michael D, Tang, Walfred WC, Kobayashi, Toshihiro, Wong, Frederick CK, Bergmann, Sophie, Slatery, Erin, Boroviak, Thorsten E, Marioni, John C, Surani, M Azim
Publicado 2023

Principles of early human development and germ cell program from conserved model systems

por Kobayashi, Toshihiro, Zhang, Haixin, Tang, Walfred W.C., Irie, Naoko, Withey, Sarah, Klisch, Doris, Sybirna, Anastasiya, Dietmann, Sabine, Contreras, David A., Webb, Robert, Allegrucci, Cinzia, Alberio, Ramiro, Surani, M. Azim
Publicado 2017

Derivation of hypermethylated pluripotent embryonic stem cells with high potency

por Bao, Siqin, Tang, Walfred WC, Wu, Baojiang, Kim, Shinseog, Li, Jingyun, Li, Lin, Kobayashi, Toshihiro, Lee, Caroline, Chen, Yanglin, Wei, Mengyi, Li, Shudong, Dietmann, Sabine, Tang, Fuchou, Li, Xihe, Surani, M Azim
Publicado 2018

SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling

por Sun, Dawei, Llora Batlle, Oriol, van den Ameele, Jelle, Thomas, John C, He, Peng, Lim, Kyungtae, Tang, Walfred, Xu, Chufan, Meyer, Kerstin B, Teichmann, Sarah A, Marioni, John C, Jackson, Stephen P, Brand, Andrea H, Rawlins, Emma L
Publicado 2022