Intracellular Drug Delivery Process of Am80-Encapsulated Lipid Nanoparticles Aiming for Alveolar Regeneration

por Akita, Tomomi, Oda, Kazuaki, Narukawa, Satoru, Morita, Yuki, Tange, Kota, Nakai, Yuta, Yamashita, Chikamasa
Publicado 2023

Am80-Encapsulated Lipid Nanoparticles, Developed with the Aim of Achieving Alveolar Regeneration, Have an Improvement Effect on Pulmonary Emphysema

por Akita, Tomomi, Morita, Yuki, Kawai, Takehiro, Oda, Kazuaki, Tange, Kota, Nakai, Yuta, Yamashita, Chikamasa
Publicado 2022

Development of an Alcohol Dilution–Lyophilization Method for the Preparation of mRNA-LNPs with Improved Storage Stability

por Shirane, Daiki, Tanaka, Hiroki, Sakurai, Yu, Taneichi, Sakura, Nakai, Yuta, Tange, Kota, Ishii, Itsuko, Akita, Hidetaka
Publicado 2023

Improvement of mRNA Delivery Efficiency to a T Cell Line by Modulating PEG-Lipid Content and Phospholipid Components of Lipid Nanoparticles

por Tanaka, Hiroki, Miyama, Ryo, Sakurai, Yu, Tamagawa, Shinya, Nakai, Yuta, Tange, Kota, Yoshioka, Hiroki, Akita, Hidetaka
Publicado 2021

Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material

por Tanaka, Hiroki, Takata, Nae, Sakurai, Yu, Yoshida, Tokuyuki, Inoue, Takao, Tamagawa, Shinya, Nakai, Yuta, Tange, Kota, Yoshioka, Hiroki, Maeki, Masatoshi, Tokeshi, Manabu, Akita, Hidetaka
Publicado 2021

Tolerogenic Lipid Nanoparticles for Delivering Self-Antigen mRNA for the Treatment of Experimental Autoimmune Encephalomyelitis

por Gomi, Masaki, Nakayama, Yuka, Sakurai, Yu, Oyama, Ryotaro, Iwasaki, Koki, Doi, Mizuki, Liu, Yi, Hori, Mizuho, Watanabe, Himeka, Hashimoto, Kohei, Tanaka, Hiroki, Tange, Kota, Nakai, Yuta, Akita, Hidetaka
Publicado 2023

pH-Responsive Lipid Nanoparticles Achieve Efficient mRNA Transfection in Brain Capillary Endothelial Cells

por Sakurai, Yu, Watanabe, Himeka, Nishio, Kazuma, Hashimoto, Kohei, Harada, Atsuki, Gomi, Masaki, Suzuki, Masayoshi, Oyama, Ryotaro, Handa, Takumi, Sato, Risa, Takeuchi, Hina, Taira, Ryoga, Tezuka, Kenta, Tange, Kota, Nakai, Yuta, Akita, Hidetaka, Uchida, Yasuo
Publicado 2022

An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses

por Oyama, Ryotaro, Ishigame, Harumichi, Tanaka, Hiroki, Tateshita, Naho, Itazawa, Moeko, Imai, Ryosuke, Nishiumi, Naomasa, Kishikawa, Jun-ichi, Kato, Takayuki, Anindita, Jessica, Nishikawa, Yoshifumi, Maeki, Masatoshi, Tokeshi, Manabu, Tange, Kota, Nakai, Yuta, Sakurai, Yu, Okada, Takaharu, Akita, Hidetaka
Publicado 2023